| 1 |
ACUTA CAPITAL PARTNERS, LLC |
1,554,146 |
21,851,000 |
28.53% |
|
|
| 2 |
PARAGON ASSOCIATES & PARAGON ASSOCIATES II JOINT VENTURE |
1,250,000 |
17,575,000 |
22.95% |
|
|
| 3 |
VANGUARD GROUP INC |
360,479 |
5,069,000 |
6.62% |
|
|
| 4 |
DIMENSIONAL FUND ADVISORS LP |
245,833 |
3,456,000 |
4.51% |
|
|
| 5 |
BlackRock Fund Advisors |
243,500 |
3,424,000 |
4.47% |
|
|
| 6 |
Ghost Tree Capital, LLC |
200,000 |
2,812,000 |
3.67% |
|
|
| 7 |
RENAISSANCE TECHNOLOGIES LLC |
195,900 |
2,754,000 |
3.60% |
|
|
| 8 |
NEXT CENTURY GROWTH INVESTORS LLC |
175,000 |
2,460,000 |
3.21% |
|
|
| 9 |
WASATCH ADVISORS LP |
110,000 |
1,547,000 |
2.02% |
|
|
| 10 |
NORTHERN TRUST CORP |
103,150 |
1,450,000 |
1.89% |
|
|
| 11 |
PERKINS CAPITAL MANAGEMENT INC |
96,500 |
1,357,000 |
1.77% |
|
|
| 12 |
STATE STREET CORP |
86,809 |
1,219,000 |
1.59% |
|
|
| 13 |
Informed Momentum Co LLC |
84,609 |
1,190,000 |
1.55% |
|
|
| 14 |
Manatuck Hill Partners, LLC |
65,000 |
914,000 |
1.19% |
|
|
| 15 |
MORGAN STANLEY |
61,175 |
861,000 |
1.12% |
|
|
| 16 |
GSA CAPITAL PARTNERS LLP |
56,322 |
792,000 |
1.03% |
|
|
| 17 |
BRIDGEWAY CAPITAL MANAGEMENT, LLC |
55,800 |
785,000 |
1.02% |
|
|
| 18 |
BlackRock Institutional Trust Company, N.A. |
51,248 |
721,000 |
0.94% |
|
|
| 19 |
ISTHMUS PARTNERS, LLC |
45,624 |
641,000 |
0.84% |
|
|
| 20 |
GEODE CAPITAL MANAGEMENT, LLC |
43,220 |
607,000 |
0.79% |
|
|
| 21 |
MILLENNIUM MANAGEMENT LLC |
37,548 |
528,000 |
0.69% |
|
|
| 22 |
WELLS FARGO & COMPANY/MN |
36,705 |
516,000 |
0.67% |
|
|
| 23 |
OBERWEIS ASSET MANAGEMENT INC/ |
35,000 |
492,000 |
0.64% |
|
|
| 24 |
CALIFORNIA PUBLIC EMPLOYEES RETIREMENT SYSTEM |
32,100 |
451,000 |
0.59% |
|
|
| 25 |
BlackRock Investment Management, LLC |
27,758 |
390,000 |
0.51% |
|
|
| 26 |
TIAA CREF INVESTMENT MANAGEMENT LLC |
24,796 |
349,000 |
0.46% |
|
|
| 27 |
PERCEPTIVE ADVISORS LLC |
21,885 |
308,000 |
0.40% |
|
|
| 28 |
Bank of New York Mellon Corp |
20,466 |
288,000 |
0.38% |
|
|
| 29 |
RUSSELL INVESTMENTS GROUP, LTD. |
17,813 |
248,000 |
0.32% |
|
|
| 30 |
CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM |
15,512 |
218,000 |
0.28% |
|
|
| 31 |
SUSQUEHANNA INTERNATIONAL GROUP, LLP |
12,600 |
177,000 |
0.23% |
|
|
| 32 |
DEUTSCHE BANK AG\ |
12,454 |
174,000 |
0.23% |
|
|
| 33 |
CHARLES SCHWAB INVESTMENT MANAGEMENT INC |
12,100 |
171,000 |
0.22% |
|
|
| 34 |
TEACHERS ADVISORS, LLC |
12,066 |
170,000 |
0.22% |
|
|
| 35 |
THOMPSON DAVIS & CO., INC. |
6,300 |
89,000 |
0.12% |
|
|
| 36 |
CITIGROUP INC |
5,867 |
82,000 |
0.11% |
|
|
| 37 |
Nationwide Fund Advisors |
4,741 |
67,000 |
0.09% |
|
|
| 38 |
NEW YORK STATE COMMON RETIREMENT FUND |
4,400 |
62,000 |
0.08% |
|
|
| 39 |
FineMark National Bank & Trust |
4,365 |
61,000 |
0.08% |
|
|
| 40 |
AMERICAN INTERNATIONAL GROUP, INC. |
4,335 |
61,000 |
0.08% |
|
|
| 41 |
UBS Group AG |
2,816 |
39,000 |
0.05% |
|
|
| 42 |
BLACKROCK ADVISORS LLC |
2,608 |
37,000 |
0.05% |
|
|
| 43 |
STRS OHIO |
2,400 |
33,000 |
0.04% |
|
|
| 44 |
MANUFACTURERS LIFE INSURANCE COMPANY, THE |
1,978 |
28,000 |
0.04% |
|
|
| 45 |
Legal & General Group Plc |
1,430 |
20,000 |
0.03% |
|
|
| 46 |
BANK OF AMERICA CORP /DE/ |
1,037 |
15,000 |
0.02% |
|
|
| 47 |
Tower Research Capital LLC (TRC) |
864 |
12,000 |
0.02% |
|
|
| 48 |
ROYAL BANK OF CANADA |
444 |
6,000 |
0.01% |
|
|
| 49 |
BNP PARIBAS FINANCIAL MARKETS |
410 |
5,765 |
0.01% |
|
|
| 50 |
BlackRock Finance, Inc. |
267 |
4,000 |
0.01% |
|
|
