| 1 |
FMR LLC |
5,527,207 |
11,607,000 |
46.64% |
|
|
| 2 |
ORACLE INVESTMENT MANAGEMENT INC |
4,863,914 |
10,214,000 |
41.04% |
|
|
| 3 |
SABBY MANAGEMENT, LLC |
302,837 |
636,000 |
2.56% |
|
|
| 4 |
Alyeska Investment Group, L.P. |
197,429 |
415,000 |
1.67% |
|
|
| 5 |
RENAISSANCE TECHNOLOGIES LLC |
179,300 |
377,000 |
1.51% |
|
|
| 6 |
HOLLENCREST CAPITAL MANAGEMENT |
162,196 |
341,000 |
1.37% |
|
|
| 7 |
Birchview Capital, LP |
145,746 |
306,000 |
1.23% |
|
|
| 8 |
DEUTSCHE BANK AG\ |
126,900 |
266,000 |
1.07% |
|
|
| 9 |
SPHERA FUNDS MANAGEMENT LTD. |
70,273 |
148,000 |
0.59% |
|
|
| 10 |
DAFNA Capital Management LLC |
59,222 |
124,000 |
0.50% |
|
|
| 11 |
Virtu KCG Holdings LLC |
46,591 |
98,000 |
0.39% |
|
|
| 12 |
VESTOR CAPITAL, LLC |
42,600 |
89,000 |
0.36% |
|
|
| 13 |
PNC FINANCIAL SERVICES GROUP, INC. |
23,400 |
49,000 |
0.20% |
|
|
| 14 |
FineMark National Bank & Trust |
22,807 |
48,000 |
0.19% |
|
|
| 15 |
Plante Moran Financial Advisors, LLC |
17,034 |
36,000 |
0.14% |
|
|
| 16 |
CIBC WORLD MARKET INC. |
15,873 |
33,000 |
0.13% |
|
|
| 17 |
GEODE CAPITAL MANAGEMENT, LLC |
12,318 |
25,000 |
0.10% |
|
|
| 18 |
CITADEL ADVISORS LLC |
11,255 |
24,000 |
0.10% |
|
|
| 19 |
TFS CAPITAL LLC |
10,033 |
21,000 |
0.08% |
|
|
| 20 |
FIFTH THIRD BANCORP |
3,900 |
8,000 |
0.03% |
|
|
| 21 |
MORGAN STANLEY |
3,226 |
7,000 |
0.03% |
|
|
| 22 |
Walleye Trading LLC |
2,500 |
5,000 |
0.02% |
|
|
| 23 |
CANADA LIFE ASSURANCE Co |
408 |
3,000 |
0.01% |
|
|
| 24 |
Bray Capital Advisors |
800 |
2,000 |
0.01% |
|
|
| 25 |
ROYAL BANK OF CANADA |
640 |
2,000 |
0.01% |
|
|
| 26 |
BANK OF MONTREAL /CAN/ |
462 |
1,000 |
0.00% |
|
|
| 27 |
1832 Asset Management L.P. |
92 |
0 |
0.00% |
|
|
| 28 |
WEALTHFRONT CORP |
7 |
0 |
0.00% |
|
|
| 29 |
BANK OF AMERICA CORP /DE/ |
100 |
0 |
0.00% |
|
|
| 30 |
TORONTO DOMINION BANK |
74 |
0 |
0.00% |
|
|
