Dark
Light
System
Security
VERTEX PHARMACEUTICALS INC
VERTEX PHARMACEUTICALS INC. Institutional holdings reported to the SEC.

Institutional Holders (2016Q3)
Portfolio Summary: 516 Institutional holders with a total value of $20,895,147,434.
#
Manager Name
Shares
Value ($)
%
Options
Notes
501 Bank of New York Mellon Corp 3,035,714 264,746,000 1.27%
502 Invesco Ltd. 3,066,951 267,470,000 1.28%
503 GOLDMAN SACHS GROUP INC 3,594,703 313,494,000 1.50%
504 WADDELL & REED FINANCIAL INC 4,041,848 352,489,000 1.69%
505 JENNISON ASSOCIATES LLC 5,180,761 451,814,000 2.16%
506 BlackRock Fund Advisors 6,262,876 546,185,000 2.61%
507 BlackRock Institutional Trust Company, N.A. 6,492,221 566,187,000 2.71%
508 Clearbridge Investments, LLC 7,299,009 636,547,000 3.05%
509 AMERIPRISE FINANCIAL INC 8,695,431 758,327,000 3.63%
510 STATE STREET CORP 8,779,211 765,638,000 3.66%
511 JPMORGAN CHASE & CO 11,027,089 962,112,000 4.60%
512 WELLINGTON MANAGEMENT GROUP LLP 14,423,839 1,257,901,000 6.02%
513 VANGUARD GROUP INC 15,602,091 1,360,659,000 6.51%
514 Capital World Investors 22,292,383 1,944,119,000 9.30%
515 FMR LLC 22,937,743 2,000,399,000 9.57%
516 PRICE T ROWE ASSOCIATES INC /MD/ 23,483,388 2,047,986,000 9.80%
Page 11 of 11

From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.