| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | FEDERATED HERMES, INC. | 34,115,000 | 54,584,000 | 19.32% | ||
| 2 | RA CAPITAL MANAGEMENT, L.P. | 14,036,590 | 22,459,000 | 7.95% | ||
| 3 | WESTFIELD CAPITAL MANAGEMENT CO LP | 13,668,111 | 21,869,000 | 7.74% | ||
| 4 | Polar Capital LLP | 10,946,861 | 17,508,000 | 6.20% | ||
| 5 | STATE STREET CORP | 10,146,462 | 16,235,000 | 5.75% | ||
| 6 | VANGUARD GROUP INC | 9,101,496 | 14,562,000 | 5.15% | ||
| 7 | BlackRock Institutional Trust Company, N.A. | 8,258,043 | 13,213,000 | 4.68% | ||
| 8 | FRANKLIN RESOURCES INC | 7,879,100 | 12,607,000 | 4.46% | ||
| 9 | Broadfin Capital, LLC | 7,660,100 | 12,256,000 | 4.34% | ||
| 10 | BlackRock Fund Advisors | 6,579,533 | 10,527,000 | 3.73% | ||
| 11 | PUTNAM INVESTMENTS LLC | 6,449,368 | 10,319,000 | 3.65% | ||
| 12 | Bain Capital Public Equity Management, LLC | 5,274,936 | 8,440,000 | 2.99% | ||
| 13 | Amici Capital, LLC | 4,876,100 | 7,802,000 | 2.76% | ||
| 14 | NORTHERN TRUST CORP | 2,971,384 | 4,754,000 | 1.68% | ||
| 15 | CLOUGH CAPITAL PARTNERS L P | 2,680,700 | 4,289,000 | 1.52% | ||
| 16 | D. E. Shaw & Co., Inc. | 2,240,537 | 3,585,000 | 1.27% | ||
| 17 | AMERIPRISE FINANCIAL INC | 2,024,748 | 3,240,000 | 1.15% | ||
| 18 | PANAGORA ASSET MANAGEMENT INC | 1,779,517 | 2,846,000 | 1.01% | ||
| 19 | MILLENNIUM MANAGEMENT LLC | 1,652,243 | 2,644,000 | 0.94% | ||
| 20 | BLAIR WILLIAM & CO/IL | 1,543,163 | 2,468,000 | 0.87% | ||
| 21 | MORGAN STANLEY | 1,529,999 | 2,448,000 | 0.87% | ||
| 22 | GEODE CAPITAL MANAGEMENT, LLC | 1,436,343 | 2,298,000 | 0.81% | ||
| 23 | Bank of New York Mellon Corp | 1,251,313 | 2,002,000 | 0.71% | ||
| 24 | Rhenman & Partners Asset Management AB | 1,228,354 | 1,965,000 | 0.70% | ||
| 25 | TIAA CREF INVESTMENT MANAGEMENT LLC | 1,196,007 | 1,914,000 | 0.68% | ||
| 26 | KENNEDY CAPITAL MANAGEMENT LLC | 1,169,944 | 1,872,000 | 0.66% | ||
| 27 | RENAISSANCE TECHNOLOGIES LLC | 1,139,293 | 1,823,000 | 0.65% | ||
| 28 | KINGDON CAPITAL MANAGEMENT, L.L.C. | 1,044,375 | 1,661,000 | 0.59% | ||
| 29 | BlackRock Investment Management, LLC | 863,672 | 1,382,000 | 0.49% | ||
| 30 | BLACKROCK ADVISORS LLC | 816,161 | 1,306,000 | 0.46% | ||
| 31 | DEUTSCHE BANK AG\ | 764,138 | 1,222,000 | 0.43% | ||
| 32 | OXFORD ASSET MANAGEMENT LLP | 686,148 | 1,086,000 | 0.38% | ||
| 33 | CADENCE CAPITAL MANAGEMENT LLC | 663,144 | 1,061,000 | 0.38% | ||
| 34 | CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 490,500 | 785,000 | 0.28% | ||
| 35 | CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 479,491 | 767,000 | 0.27% | ||
| 36 | MHR FUND MANAGEMENT LLC | 445,000 | 712,000 | 0.25% | ||
| 37 | HOWARD HUGHES MEDICAL INSTITUTE | 433,557 | 694,000 | 0.25% | ||
| 38 | ALLIANCEBERNSTEIN L.P. | 425,300 | 680,000 | 0.24% | ||
| 39 | CREDIT SUISSE AG/ | 391,186 | 626,000 | 0.22% | ||
| 40 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 372,800 | 596,000 | 0.21% | Call | |
| 41 | TEACHERS ADVISORS, LLC | 359,046 | 574,000 | 0.20% | ||
| 42 | Neuberger Berman Group LLC | 310,500 | 497,000 | 0.18% | ||
| 43 | RHUMBLINE ADVISERS | 308,220 | 493,000 | 0.17% | ||
| 44 | Swiss National Bank | 271,400 | 434,000 | 0.15% | ||
| 45 | TURNER INVESTMENTS LLC | 238,130 | 381,000 | 0.13% | ||
| 46 | PRICE T ROWE ASSOCIATES INC /MD/ | 205,800 | 329,000 | 0.12% | ||
| 47 | Nationwide Fund Advisors | 203,396 | 325,000 | 0.12% | ||
| 48 | NOMURA HOLDINGS INC | 202,733 | 319,000 | 0.11% | ||
| 49 | MANUFACTURERS LIFE INSURANCE COMPANY, THE | 176,144 | 282,000 | 0.10% | ||
| 50 | WELLS FARGO & COMPANY/MN | 172,441 | 276,000 | 0.10% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
