| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | FEDERATED HERMES, INC. | 34,115,000 | 48,784,000 | 20.86% | ||
| 2 | WESTFIELD CAPITAL MANAGEMENT CO LP | 17,675,041 | 25,275,000 | 10.81% | ||
| 3 | RA CAPITAL MANAGEMENT, L.P. | 12,179,002 | 17,416,000 | 7.45% | ||
| 4 | Polar Capital LLP | 11,393,507 | 16,293,000 | 6.97% | ||
| 5 | VANGUARD GROUP INC | 10,465,095 | 14,965,000 | 6.40% | ||
| 6 | BlackRock Institutional Trust Company, N.A. | 8,476,590 | 12,122,000 | 5.18% | ||
| 7 | Broadfin Capital, LLC | 7,660,100 | 10,954,000 | 4.68% | ||
| 8 | PUTNAM INVESTMENTS LLC | 7,149,941 | 10,224,000 | 4.37% | ||
| 9 | FRANKLIN RESOURCES INC | 6,537,800 | 9,349,000 | 4.00% | ||
| 10 | Amici Capital, LLC | 6,334,100 | 9,058,000 | 3.87% | ||
| 11 | BlackRock Fund Advisors | 6,234,826 | 8,916,000 | 3.81% | ||
| 12 | CLOUGH CAPITAL PARTNERS L P | 4,381,600 | 6,266,000 | 2.68% | ||
| 13 | NORTHERN TRUST CORP | 2,822,701 | 4,037,000 | 1.73% | ||
| 14 | D. E. Shaw & Co., Inc. | 2,183,712 | 3,123,000 | 1.34% | ||
| 15 | AMERIPRISE FINANCIAL INC | 1,917,575 | 2,742,000 | 1.17% | ||
| 16 | MILLENNIUM MANAGEMENT LLC | 1,824,693 | 2,609,000 | 1.12% | ||
| 17 | BLAIR WILLIAM & CO/IL | 1,574,263 | 2,250,000 | 0.96% | ||
| 18 | GEODE CAPITAL MANAGEMENT, LLC | 1,477,228 | 2,112,000 | 0.90% | ||
| 19 | MORGAN STANLEY | 1,456,407 | 2,082,000 | 0.89% | ||
| 20 | Bank of New York Mellon Corp | 1,427,285 | 2,042,000 | 0.87% | ||
| 21 | Rhenman & Partners Asset Management AB | 1,228,354 | 1,757,000 | 0.75% | ||
| 22 | TIAA CREF INVESTMENT MANAGEMENT LLC | 1,162,996 | 1,663,000 | 0.71% | ||
| 23 | KENNEDY CAPITAL MANAGEMENT LLC | 1,151,283 | 1,646,000 | 0.70% | ||
| 24 | KINGDON CAPITAL MANAGEMENT, L.L.C. | 1,044,375 | 1,493,000 | 0.64% | ||
| 25 | BlackRock Investment Management, LLC | 872,723 | 1,248,000 | 0.53% | ||
| 26 | WELLINGTON MANAGEMENT GROUP LLP | 847,900 | 1,212,000 | 0.52% | ||
| 27 | DEUTSCHE BANK AG\ | 772,755 | 1,103,000 | 0.47% | ||
| 28 | TURNER INVESTMENTS LLC | 514,940 | 736,000 | 0.31% | ||
| 29 | GOLDMAN SACHS GROUP INC | 496,751 | 711,000 | 0.30% | ||
| 30 | CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 490,500 | 702,000 | 0.30% | ||
| 31 | CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 485,246 | 694,000 | 0.30% | ||
| 32 | MHR FUND MANAGEMENT LLC | 445,000 | 636,000 | 0.27% | ||
| 33 | HOWARD HUGHES MEDICAL INSTITUTE | 433,557 | 620,000 | 0.27% | ||
| 34 | ALLIANCEBERNSTEIN L.P. | 425,300 | 608,000 | 0.26% | ||
| 35 | OXFORD ASSET MANAGEMENT LLP | 412,330 | 593,000 | 0.25% | ||
| 36 | TEACHERS ADVISORS, LLC | 359,046 | 513,000 | 0.22% | ||
| 37 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 295,600 | 423,000 | 0.18% | Call | |
| 38 | Swiss National Bank | 271,400 | 388,000 | 0.17% | ||
| 39 | CREDIT AGRICOLE S A | 242,281 | 346,000 | 0.15% | ||
| 40 | METROPOLITAN LIFE INSURANCE CO/NY | 215,414 | 308,000 | 0.13% | ||
| 41 | PRICE T ROWE ASSOCIATES INC /MD/ | 205,800 | 294,000 | 0.13% | ||
| 42 | Nationwide Fund Advisors | 203,273 | 291,000 | 0.12% | ||
| 43 | PNC FINANCIAL SERVICES GROUP, INC. | 185,790 | 265,000 | 0.11% | ||
| 44 | MANUFACTURERS LIFE INSURANCE COMPANY, THE | 172,700 | 247,000 | 0.11% | ||
| 45 | AMERICAN INTERNATIONAL GROUP, INC. | 171,929 | 245,858 | 0.11% | ||
| 46 | VOYA INVESTMENT MANAGEMENT LLC | 171,154 | 245,000 | 0.10% | ||
| 47 | BLACKROCK ADVISORS LLC | 161,800 | 231,000 | 0.10% | ||
| 48 | CALIFORNIA PUBLIC EMPLOYEES RETIREMENT SYSTEM | 158,100 | 226,000 | 0.10% | ||
| 49 | WELLS FARGO & COMPANY/MN | 151,108 | 216,000 | 0.09% | ||
| 50 | STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM | 140,798 | 201,000 | 0.09% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
