| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | BAUPOST GROUP LLC/MA | 6,310,850 | 107,537,000 | 9.10% | ||
| 2 | VANGUARD GROUP INC | 4,120,180 | 70,208,000 | 5.94% | ||
| 3 | FMR LLC | 3,650,200 | 62,199,000 | 5.26% | ||
| 4 | SECTORAL ASSET MANAGEMENT INC | 3,537,590 | 60,281,000 | 5.10% | ||
| 5 | FRANKLIN RESOURCES INC | 3,042,400 | 51,842,000 | 4.39% | ||
| 6 | WELLS FARGO & COMPANY/MN | 2,840,923 | 48,410,000 | 4.10% | ||
| 7 | STATE STREET CORP | 2,824,904 | 48,134,000 | 4.07% | ||
| 8 | BlackRock Institutional Trust Company, N.A. | 2,560,460 | 43,630,000 | 3.69% | ||
| 9 | BlackRock Fund Advisors | 2,501,741 | 42,630,000 | 3.61% | ||
| 10 | OAK RIDGE INVESTMENTS LLC | 2,067,053 | 35,223,000 | 2.98% | ||
| 11 | Invesco Ltd. | 1,654,443 | 28,192,000 | 2.39% | ||
| 12 | SAC Capital Advisors LP | 1,525,058 | 25,987,000 | 2.20% | ||
| 13 | Allianz Asset Management GmbH | 1,523,066 | 25,953,000 | 2.20% | ||
| 14 | DEERFIELD MANAGEMENT COMPANY, L.P. | 1,403,105 | 23,909,000 | 2.02% | ||
| 15 | EAGLE ASSET MANAGEMENT INC | 1,347,341 | 22,958,000 | 1.94% | ||
| 16 | Foresite Capital Management I, LLC | 1,312,006 | 22,357,000 | 1.89% | ||
| 17 | Camber Capital Management LP | 1,250,000 | 21,300,000 | 1.80% | ||
| 18 | UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 1,226,896 | 20,906,000 | 1.77% | ||
| 19 | JPMORGAN CHASE & CO | 1,175,874 | 20,036,000 | 1.70% | ||
| 20 | NORTHERN TRUST CORP | 1,168,578 | 19,912,000 | 1.69% | ||
| 21 | AMERIPRISE FINANCIAL INC | 1,008,172 | 17,178,000 | 1.45% | ||
| 22 | VHCP Management, LLC | 1,000,273 | 17,045,000 | 1.44% | ||
| 23 | STIFEL FINANCIAL CORP | 955,107 | 16,275,000 | 1.38% | ||
| 24 | HARVEY CAPITAL MANAGEMENT INC | 915,800 | 15,605,000 | 1.32% | ||
| 25 | Apex Capital Management | 904,313 | 15,409,000 | 1.30% | ||
| 26 | NORTHPOINTE CAPITAL LLC | 877,875 | 14,958,000 | 1.27% | ||
| 27 | QVT Financial LP | 835,200 | 14,232,000 | 1.20% | ||
| 28 | OppenheimerFunds, Inc. | 822,265 | 14,011,000 | 1.19% | ||
| 29 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 725,600 | 12,365,000 | 1.05% | Call | |
| 30 | JANUS HENDERSON INVESTORS US LLC | 654,234 | 11,148,000 | 0.94% | ||
| 31 | INSIGHT CAPITAL RESEARCH & MANAGEMENT INC | 587,504 | 10,011,000 | 0.85% | ||
| 32 | Bank of New York Mellon Corp | 534,932 | 9,116,000 | 0.77% | ||
| 33 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 509,000 | 8,673,000 | 0.73% | Put | |
| 34 | GEODE CAPITAL MANAGEMENT, LLC | 493,041 | 8,401,000 | 0.71% | ||
| 35 | LORD, ABBETT & CO. LLC | 431,201 | 7,348,000 | 0.62% | ||
| 36 | MANAGED ACCOUNT ADVISORS LLC | 412,180 | 7,023,000 | 0.59% | ||
| 37 | TIAA CREF INVESTMENT MANAGEMENT LLC | 340,090 | 5,795,000 | 0.49% | ||
| 38 | Cupps Capital Management, LLC | 319,275 | 5,440,000 | 0.46% | ||
| 39 | Nationwide Fund Advisors | 300,581 | 5,122,000 | 0.43% | ||
| 40 | GUGGENHEIM CAPITAL LLC | 296,817 | 5,058,000 | 0.43% | ||
| 41 | AMUNDI ASSET MANAGEMENT US, INC. | 284,299 | 4,844,000 | 0.41% | ||
| 42 | PERCEPTIVE ADVISORS LLC | 275,000 | 4,686,000 | 0.40% | ||
| 43 | PRINCIPAL FINANCIAL GROUP INC | 268,222 | 4,571,000 | 0.39% | ||
| 44 | Rhenman & Partners Asset Management AB | 265,325 | 4,521,000 | 0.38% | ||
| 45 | BARCLAYS PLC | 265,000 | 4,505,000 | 0.38% | Call | |
| 46 | A.R.T. Advisors, LLC | 259,439 | 4,420,000 | 0.37% | ||
| 47 | BlackRock Investment Management, LLC | 246,129 | 4,194,000 | 0.35% | ||
| 48 | WEXFORD CAPITAL LP | 243,335 | 4,146,000 | 0.35% | ||
| 49 | Informed Momentum Co LLC | 230,784 | 3,933,000 | 0.33% | ||
| 50 | CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 230,714 | 3,932,000 | 0.33% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
