| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | Aisling Capital LLC | 8,335,819 | 18,839,000 | 18.64% | ||
| 2 | SV Health Investors, LLC | 7,546,692 | 17,056,000 | 16.87% | ||
| 3 | JPMORGAN CHASE & CO | 3,750,000 | 8,475,000 | 8.38% | ||
| 4 | StepStone Group LP | 3,480,512 | 7,866,000 | 7.78% | ||
| 5 | MASTERS CAPITAL MANAGEMENT LLC | 3,000,000 | 6,780,000 | 6.71% | ||
| 6 | CITADEL ADVISORS LLC | 1,965,470 | 4,442,000 | 4.39% | ||
| 7 | GOLDMAN SACHS GROUP INC | 1,861,200 | 4,206,000 | 4.16% | Call | |
| 8 | PERCEPTIVE ADVISORS LLC | 1,826,432 | 4,127,000 | 4.08% | ||
| 9 | SABBY MANAGEMENT, LLC | 1,591,117 | 3,596,000 | 3.56% | ||
| 10 | VANGUARD GROUP INC | 1,392,987 | 3,148,000 | 3.11% | ||
| 11 | BlackRock Fund Advisors | 1,100,019 | 2,486,000 | 2.46% | ||
| 12 | BLACKROCK ADVISORS LLC | 1,096,757 | 2,479,000 | 2.45% | ||
| 13 | PURA VIDA INVESTMENTS, LLC | 810,404 | 1,832,000 | 1.81% | ||
| 14 | C WorldWide Group Holding A/S | 637,169 | 1,440,000 | 1.42% | ||
| 15 | GOLDMAN SACHS GROUP INC | 547,673 | 1,238,000 | 1.22% | ||
| 16 | PUTNAM INVESTMENTS LLC | 520,757 | 1,177,000 | 1.16% | ||
| 17 | BlackRock Institutional Trust Company, N.A. | 486,846 | 1,100,000 | 1.09% | ||
| 18 | BlackRock Group LTD | 422,232 | 954,000 | 0.94% | ||
| 19 | NORTHERN TRUST CORP | 410,399 | 928,000 | 0.92% | ||
| 20 | STATE STREET CORP | 389,779 | 880,000 | 0.87% | ||
| 21 | Vident Investment Advisory, LLC | 361,003 | 816,000 | 0.81% | ||
| 22 | BlackRock Investment Management, LLC | 331,647 | 750,000 | 0.74% | ||
| 23 | GEODE CAPITAL MANAGEMENT, LLC | 312,993 | 707,000 | 0.70% | ||
| 24 | TFS CAPITAL LLC | 281,782 | 637,000 | 0.63% | ||
| 25 | BRIDGEWAY CAPITAL MANAGEMENT, LLC | 234,942 | 531,000 | 0.53% | ||
| 26 | Granite Investment Partners, LLC | 231,966 | 523,000 | 0.52% | ||
| 27 | Bank of New York Mellon Corp | 225,009 | 509,000 | 0.50% | ||
| 28 | BlackRock Finance, Inc. | 203,297 | 460,000 | 0.46% | ||
| 29 | TIAA CREF INVESTMENT MANAGEMENT LLC | 143,047 | 323,000 | 0.32% | ||
| 30 | ROYAL BANK OF CANADA | 136,011 | 307,000 | 0.30% | ||
| 31 | MORGAN STANLEY | 121,431 | 274,000 | 0.27% | ||
| 32 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 94,500 | 214,000 | 0.21% | Call | |
| 33 | CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 81,386 | 184,000 | 0.18% | ||
| 34 | MILLENNIUM MANAGEMENT LLC | 74,676 | 169,000 | 0.17% | ||
| 35 | DEERFIELD MANAGEMENT COMPANY, L.P. | 61,819 | 140,000 | 0.14% | ||
| 36 | HIGHBRIDGE CAPITAL MANAGEMENT LLC | 59,536 | 135,000 | 0.13% | ||
| 37 | TEACHERS ADVISORS, LLC | 54,863 | 124,000 | 0.12% | ||
| 38 | RHUMBLINE ADVISERS | 54,684 | 124,000 | 0.12% | ||
| 39 | PRUDENTIAL FINANCIAL INC | 45,800 | 104,000 | 0.10% | ||
| 40 | CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 42,100 | 96,000 | 0.09% | ||
| 41 | DOHENY ASSET MANAGEMENT /CA | 39,000 | 88,000 | 0.09% | ||
| 42 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 36,889 | 83,000 | 0.08% | ||
| 43 | STIFEL FINANCIAL CORP | 34,000 | 77,000 | 0.08% | ||
| 44 | NEW YORK STATE COMMON RETIREMENT FUND | 31,700 | 72,000 | 0.07% | ||
| 45 | PARAMETRIC PORTFOLIO ASSOCIATES LLC | 29,970 | 68,000 | 0.07% | ||
| 46 | OXFORD ASSET MANAGEMENT LLP | 27,742 | 63,000 | 0.06% | ||
| 47 | DIMENSIONAL FUND ADVISORS LP | 26,629 | 60,000 | 0.06% | ||
| 48 | Nationwide Fund Advisors | 26,380 | 60,000 | 0.06% | ||
| 49 | AMERICAN INTERNATIONAL GROUP, INC. | 20,394 | 46,000 | 0.05% | ||
| 50 | Mariner, LLC | 20,000 | 45,000 | 0.04% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
