| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | AMICUS THERAPEUTICS INC | 14,439,444 | 175,633,000 | 14.03% | ||
| 2 | NEUROCRINE BIOSCIE COM USD0.001 | 2,942,967 | 117,101,000 | 9.35% | ||
| 3 | SAREPTA THERAPEUTICS INC | 2,784,928 | 89,424,000 | 7.14% | ||
| 4 | RETROPHIN INC COM | 2,647,080 | 53,629,000 | 4.28% | ||
| 5 | TESARO INC | 981,759 | 39,368,000 | 3.14% | ||
| 6 | GLOBAL BLOOD THERAPEUTICS IN COM | 921,800 | 38,863,000 | 3.10% | ||
| 7 | DYAX CORP COM CVR | 1,646,315 | 31,428,000 | 2.51% | ||
| 8 | NEVRO CORP | 606,811 | 28,150,000 | 2.25% | ||
| 9 | GW PHARMACEUTICALS PLC | 300,000 | 27,411,000 | 2.19% | Put | |
| 10 | PTC THERAPEUTICS INC | 1,005,000 | 26,834,000 | 2.14% | Put | |
| 11 | VERSARTIS INC COM | 2,317,954 | 26,726,000 | 2.13% | ||
| 12 | ISHARES TR | 200,000 | 21,840,000 | 1.74% | Put | |
| 13 | XENCOR INC COM | 1,754,784 | 21,461,000 | 1.71% | ||
| 14 | ACELRX PHARMACEUTICALS INC | 6,264,060 | 19,105,000 | 1.53% | ||
| 15 | RELYPSA INC | 987,942 | 18,287,000 | 1.46% | ||
| 16 | LA JOLLA PHARMACEUTICAL CO | 654,515 | 18,189,000 | 1.45% | ||
| 17 | REGENXBIO INC COM | 779,213 | 17,166,000 | 1.37% | ||
| 18 | SPDR SER TR | 275,000 | 17,119,000 | 1.37% | Put | |
| 19 | Lion Biotechnologies | 2,955,456 | 17,023,000 | 1.36% | ||
| 20 | IGNYTA INC COM | 1,931,600 | 16,959,000 | 1.35% | ||
| 21 | CEMPRA INC | 582,500 | 16,217,000 | 1.30% | ||
| 22 | PFENEX INC COM | 971,043 | 14,575,000 | 1.16% | ||
| 23 | UNIQURE NV | 690,269 | 14,116,000 | 1.13% | ||
| 24 | PROSHARES TR | 200,000 | 11,120,000 | 0.89% | Put | |
| 25 | CAPITAL SR LIVING CORP COM | 553,600 | 11,100,000 | 0.89% | ||
| 26 | DERMIRA INC | 472,000 | 11,016,000 | 0.88% | ||
| 27 | DBV TECHNOLOGIES | 306,715 | 10,916,000 | 0.87% | ||
| 28 | NOVO-NORDISK A S | 200,000 | 10,848,000 | 0.87% | Put | |
| 29 | QUOTIENT LTD | 776,803 | 10,347,000 | 0.83% | ||
| 30 | GILEAD SCIENCES INC | 100,000 | 9,819,000 | 0.78% | Put | |
| 31 | ACADIA PHARMACEUTICALS | 295,240 | 9,764,000 | 0.78% | ||
| 32 | SAREPTA THERAPEUTICS INC | 300,000 | 9,634,000 | 0.77% | Call | |
| 33 | CIDARA THERAPEUTICS INC | 742,858 | 9,449,000 | 0.75% | ||
| 34 | EAGLE PHARMACEUTICALS INC COM | 123,044 | 9,109,000 | 0.73% | ||
| 35 | TEVA PHARMACEUTICAL INDS LTD | 160,000 | 9,034,000 | 0.72% | ||
| 36 | BLUEPRINT MEDICINES CORP COM | 404,404 | 8,629,000 | 0.69% | ||
| 37 | VBI Vaccines Inc. | 3,260,356 | 8,607,000 | 0.69% | ||
| 38 | SHIRE PLC | 41,000 | 8,415,000 | 0.67% | ||
| 39 | ZYNERBA PHARMACEUTICALS INC | 579,350 | 8,290,000 | 0.66% | ||
| 40 | NEOS THERAPEUTICS INC COM | 371,066 | 7,796,000 | 0.62% | ||
| 41 | ASSEMBLY BIOSCIENCES INC | 795,000 | 7,600,000 | 0.61% | ||
| 42 | BELLICUM PHARMACEUTICALS INC | 521,188 | 7,572,000 | 0.60% | ||
| 43 | NEPTUNE TECHNOLOGIES BIORESO | 6,700,444 | 7,370,000 | 0.59% | ||
| 44 | ABEONA THERAPEUTICS INC | 1,762,881 | 7,140,000 | 0.57% | ||
| 45 | ANI PHARMACEUTICALS INC | 7,500,000 | 6,923,000 | 0.55% | PRN | |
| 46 | ACCELERON PHARMA | 276,036 | 6,873,000 | 0.55% | ||
| 47 | THORATEC LABS CORP | 100,000 | 6,327,000 | 0.51% | Call | |
| 48 | ALLIQUA BIOMEDICAL INC | 1,921,951 | 6,092,000 | 0.49% | ||
| 49 | CELLECTIS S A | 218,679 | 5,764,000 | 0.46% | ||
| 50 | APPLIED GENETIC TECHNOL CORP | 850,992 | 5,591,000 | 0.45% |
Portfolio data is normalized using SEC Form 13F filings, including the Restatement filing (0001019056-15-000911, filed 2015.11.17). Although 0001019056-15-000911 is marked by the manager as a New Holdings filing, our automated system processes it as a Restatement filing.
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
