| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | Broadfin Capital, LLC | 1,977,854 | 23,042,000 | 27.31% | ||
| 2 | DEERFIELD MANAGEMENT COMPANY, L.P. | 1,415,075 | 16,486,000 | 19.54% | ||
| 3 | JPMORGAN CHASE & CO | 749,325 | 8,730,000 | 10.35% | ||
| 4 | SECTORAL ASSET MANAGEMENT INC | 660,232 | 7,692,000 | 9.12% | ||
| 5 | FEDERATED HERMES, INC. | 573,800 | 6,685,000 | 7.92% | ||
| 6 | KINGDON CAPITAL MANAGEMENT, L.L.C. | 275,000 | 3,196,000 | 3.79% | ||
| 7 | BlackRock Fund Advisors | 227,418 | 2,649,000 | 3.14% | ||
| 8 | KENNEDY CAPITAL MANAGEMENT LLC | 199,902 | 2,329,000 | 2.76% | ||
| 9 | NORGES BANK | 112,968 | 1,316,000 | 1.56% | ||
| 10 | FMR LLC | 100,000 | 1,165,000 | 1.38% | ||
| 11 | Alyeska Investment Group, L.P. | 98,974 | 1,153,000 | 1.37% | ||
| 12 | BlackRock Institutional Trust Company, N.A. | 91,825 | 1,070,000 | 1.27% | ||
| 13 | GOLDMAN SACHS GROUP INC | 82,223 | 958,000 | 1.14% | ||
| 14 | PACIFIC ALTERNATIVE ASSET MANAGEMENT COMPANY, LLC | 74,048 | 863,000 | 1.02% | ||
| 15 | MORGAN STANLEY | 69,160 | 806,000 | 0.96% | ||
| 16 | STATE STREET CORP | 65,400 | 761,000 | 0.90% | ||
| 17 | TURNER INVESTMENTS LLC | 59,580 | 694,000 | 0.82% | ||
| 18 | BOGLE INVESTMENT MANAGEMENT L P /DE/ | 52,729 | 614,000 | 0.73% | ||
| 19 | VANGUARD GROUP INC | 48,816 | 568,000 | 0.67% | ||
| 20 | Nationwide Fund Advisors | 46,028 | 536,000 | 0.64% | ||
| 21 | GEODE CAPITAL MANAGEMENT, LLC | 35,709 | 415,000 | 0.49% | ||
| 22 | BlackRock Investment Management, LLC | 25,223 | 294,000 | 0.35% | ||
| 23 | NORTHERN TRUST CORP | 22,208 | 259,000 | 0.31% | ||
| 24 | Spark Investment Management LLC | 21,200 | 246,000 | 0.29% | ||
| 25 | Bank of New York Mellon Corp | 21,042 | 246,000 | 0.29% | ||
| 26 | TFS CAPITAL LLC | 19,087 | 222,000 | 0.26% | ||
| 27 | TIAA CREF INVESTMENT MANAGEMENT LLC | 19,095 | 222,000 | 0.26% | ||
| 28 | PICTET ASSET MANAGEMENT LTD | 17,800 | 207,000 | 0.25% | ||
| 29 | CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 17,100 | 199,000 | 0.24% | ||
| 30 | CITADEL ADVISORS LLC | 15,700 | 183,000 | 0.22% | ||
| 31 | TEACHERS ADVISORS, LLC | 8,611 | 100,000 | 0.12% | ||
| 32 | PIPER SANDLER & CO. | 8,428 | 98,000 | 0.12% | ||
| 33 | BlackRock Group LTD | 8,001 | 93,000 | 0.11% | ||
| 34 | Tower Research Capital LLC (TRC) | 4,760 | 55,000 | 0.07% | ||
| 35 | BLACKROCK ADVISORS LLC | 3,450 | 40,000 | 0.05% | ||
| 36 | STRS OHIO | 3,200 | 37,000 | 0.04% | ||
| 37 | Ground Swell Capital, LLC | 2,887 | 34,000 | 0.04% | ||
| 38 | ROYAL BANK OF CANADA | 2,500 | 29,000 | 0.03% | ||
| 39 | CITIGROUP INC | 2,032 | 24,000 | 0.03% | ||
| 40 | BANK OF MONTREAL /CAN/ | 2,000 | 23,000 | 0.03% | ||
| 41 | UBS AG | 871 | 10,000 | 0.01% | ||
| 42 | BlackRock Japan Co. Ltd | 622 | 7,000 | 0.01% | ||
| 43 | MSI Financial Services Inc | 300 | 3,000 | 0.00% | ||
| 44 | MANUFACTURERS LIFE INSURANCE COMPANY, THE | 289 | 3,000 | 0.00% | ||
| 45 | DEUTSCHE BANK AG\ | 3 | 0 | 0.00% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
