| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | Broadfin Capital, LLC | 2,127,854 | 24,704,000 | 26.81% | ||
| 2 | DEERFIELD MANAGEMENT COMPANY, L.P. | 1,276,577 | 14,821,000 | 16.09% | ||
| 3 | BlackRock Fund Advisors | 776,444 | 9,015,000 | 9.78% | ||
| 4 | JPMORGAN CHASE & CO | 695,914 | 8,080,000 | 8.77% | ||
| 5 | SECTORAL ASSET MANAGEMENT INC | 660,232 | 7,665,000 | 8.32% | ||
| 6 | KINGDON CAPITAL MANAGEMENT, L.L.C. | 470,339 | 5,461,000 | 5.93% | ||
| 7 | KENNEDY CAPITAL MANAGEMENT LLC | 199,603 | 2,317,000 | 2.51% | ||
| 8 | VANGUARD GROUP INC | 155,730 | 1,808,000 | 1.96% | ||
| 9 | FEDERATED HERMES, INC. | 150,760 | 1,751,000 | 1.90% | ||
| 10 | Fiera Capital (Europe) Ltd. | 121,576 | 1,426,000 | 1.55% | ||
| 11 | Alyeska Investment Group, L.P. | 116,188 | 1,349,000 | 1.46% | ||
| 12 | Endurant Capital Management LP | 107,059 | 1,243,000 | 1.35% | ||
| 13 | FMR LLC | 100,000 | 1,161,000 | 1.26% | ||
| 14 | NORTHERN TRUST CORP | 94,728 | 1,100,000 | 1.19% | ||
| 15 | TURNER INVESTMENTS LLC | 78,890 | 916,000 | 0.99% | ||
| 16 | STATE STREET CORP | 74,400 | 864,000 | 0.94% | ||
| 17 | BlackRock Institutional Trust Company, N.A. | 73,862 | 858,000 | 0.93% | ||
| 18 | CITADEL ADVISORS LLC | 50,384 | 585,000 | 0.63% | ||
| 19 | Nationwide Fund Advisors | 47,772 | 555,000 | 0.60% | ||
| 20 | GEODE CAPITAL MANAGEMENT, LLC | 45,940 | 533,000 | 0.58% | ||
| 21 | GOLDMAN SACHS GROUP INC | 43,909 | 510,000 | 0.55% | ||
| 22 | TWO SIGMA INVESTMENTS, LP | 39,659 | 460,000 | 0.50% | ||
| 23 | Spark Investment Management LLC | 37,334 | 432,000 | 0.47% | ||
| 24 | ProShare Advisors LLC | 31,548 | 366,000 | 0.40% | ||
| 25 | GSA CAPITAL PARTNERS LLP | 30,300 | 352,000 | 0.38% | ||
| 26 | Bank of New York Mellon Corp | 27,217 | 316,000 | 0.34% | ||
| 27 | MILLENNIUM MANAGEMENT LLC | 26,422 | 307,000 | 0.33% | ||
| 28 | MORGAN STANLEY | 26,160 | 304,000 | 0.33% | ||
| 29 | BlackRock Investment Management, LLC | 25,774 | 299,000 | 0.32% | ||
| 30 | DEUTSCHE BANK AG\ | 21,705 | 251,000 | 0.27% | ||
| 31 | TIAA CREF INVESTMENT MANAGEMENT LLC | 21,562 | 250,000 | 0.27% | ||
| 32 | NORGES BANK | 17,968 | 209,000 | 0.23% | ||
| 33 | PICTET ASSET MANAGEMENT LTD | 17,800 | 207,000 | 0.22% | ||
| 34 | CREDIT SUISSE AG/ | 17,806 | 206,000 | 0.22% | ||
| 35 | CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 17,173 | 199,000 | 0.22% | ||
| 36 | Cubist Systematic Strategies, LLC | 14,073 | 163,000 | 0.18% | ||
| 37 | TFS CAPITAL LLC | 13,987 | 162,000 | 0.18% | ||
| 38 | BANQUE PICTET & CIE SA | 13,073 | 152,000 | 0.16% | ||
| 39 | CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 12,700 | 148,000 | 0.16% | ||
| 40 | CITIGROUP INC | 10,938 | 127,000 | 0.14% | ||
| 41 | US BANCORP \DE\ | 10,060 | 117,000 | 0.13% | ||
| 42 | TEACHERS ADVISORS, LLC | 8,611 | 100,000 | 0.11% | ||
| 43 | AMERICAN INTERNATIONAL GROUP, INC. | 5,809 | 67,442 | 0.07% | ||
| 44 | BLACKROCK ADVISORS LLC | 3,450 | 40,000 | 0.04% | ||
| 45 | STRS OHIO | 3,200 | 37,000 | 0.04% | ||
| 46 | Pinnacle Summer Investments, Inc. | 3,000 | 36,000 | 0.04% | ||
| 47 | ROYAL BANK OF CANADA | 2,516 | 29,000 | 0.03% | ||
| 48 | BANK OF MONTREAL /CAN/ | 2,000 | 23,000 | 0.02% | ||
| 49 | MANUFACTURERS LIFE INSURANCE COMPANY, THE | 1,342 | 16,000 | 0.02% | ||
| 50 | Tower Research Capital LLC (TRC) | 872 | 10,000 | 0.01% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
