| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | FMR LLC | 934,781 | 13,751,000 | 19.50% | ||
| 2 | MORGAN STANLEY | 556,055 | 8,135,000 | 11.54% | ||
| 3 | Abingworth LLP | 555,555 | 7,950,000 | 11.27% | ||
| 4 | Avoro Capital Advisors LLC | 497,422 | 7,277,000 | 10.32% | ||
| 5 | PUTNAM INVESTMENTS LLC | 351,000 | 5,163,000 | 7.32% | ||
| 6 | PRUDENTIAL PLC | 333,333 | 4,903,000 | 6.95% | ||
| 7 | Fortress Investment Group LLC | 277,777 | 4,064,000 | 5.76% | ||
| 8 | JENNISON ASSOCIATES LLC | 276,184 | 4,063,000 | 5.76% | ||
| 9 | C WorldWide Group Holding A/S | 245,184 | 3,587,000 | 5.09% | ||
| 10 | Alyeska Investment Group, L.P. | 240,959 | 3,525,000 | 5.00% | ||
| 11 | ACUTA CAPITAL PARTNERS, LLC | 237,287 | 3,472,000 | 4.92% | ||
| 12 | Rathbones Group PLC | 128,260 | 1,876,000 | 2.66% | ||
| 13 | Opaleye Management Inc. | 101,200 | 1,481,000 | 2.10% | ||
| 14 | Bank of New York Mellon Corp | 65,770 | 962,000 | 1.36% | ||
| 15 | Fiduciary Trust Co International of Pennsylvania | 15,725 | 230,000 | 0.33% | ||
| 16 | Evercore Wealth Management, LLC | 2,000 | 29,000 | 0.04% | ||
| 17 | Tower Research Capital LLC (TRC) | 1,529 | 22,000 | 0.03% | ||
| 18 | PNC FINANCIAL SERVICES GROUP, INC. | 1,000 | 15,000 | 0.02% | ||
| 19 | UBS Group AG | 628 | 9,000 | 0.01% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
