| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | FMR LLC | 928,881 | 11,778,000 | 19.51% | ||
| 2 | MORGAN STANLEY | 556,056 | 6,962,000 | 11.54% | ||
| 3 | Abingworth LLP | 555,555 | 6,689,000 | 11.08% | ||
| 4 | Avoro Capital Advisors LLC | 502,422 | 6,290,000 | 10.42% | ||
| 5 | PUTNAM INVESTMENTS LLC | 351,000 | 4,451,000 | 7.37% | ||
| 6 | PRUDENTIAL PLC | 334,739 | 4,244,000 | 7.03% | ||
| 7 | JENNISON ASSOCIATES LLC | 277,048 | 3,513,000 | 5.82% | ||
| 8 | Fortress Investment Group LLC | 277,777 | 3,478,000 | 5.76% | ||
| 9 | ACUTA CAPITAL PARTNERS, LLC | 273,981 | 3,430,000 | 5.68% | ||
| 10 | C WorldWide Group Holding A/S | 245,184 | 3,070,000 | 5.09% | ||
| 11 | Alyeska Investment Group, L.P. | 239,912 | 3,004,000 | 4.98% | ||
| 12 | Rathbones Group PLC | 128,260 | 1,606,000 | 2.66% | ||
| 13 | Bank of New York Mellon Corp | 70,114 | 878,000 | 1.45% | ||
| 14 | Opaleye Management Inc. | 55,543 | 695,000 | 1.15% | ||
| 15 | Fiduciary Trust Co International of Pennsylvania | 15,725 | 197,000 | 0.33% | ||
| 16 | Evercore Wealth Management, LLC | 2,000 | 25,000 | 0.04% | ||
| 17 | Tower Research Capital LLC (TRC) | 1,403 | 18,000 | 0.03% | ||
| 18 | UBS Group AG | 1,029 | 13,000 | 0.02% | ||
| 19 | PNC FINANCIAL SERVICES GROUP, INC. | 1,000 | 13,000 | 0.02% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
