| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | FMR LLC | 928,881 | 7,710,000 | 17.91% | ||
| 2 | MORGAN STANLEY | 556,055 | 4,615,000 | 10.72% | ||
| 3 | Abingworth LLP | 555,555 | 4,178,000 | 9.71% | ||
| 4 | Avoro Capital Advisors LLC | 501,722 | 4,164,000 | 9.67% | ||
| 5 | PRUDENTIAL PLC | 368,896 | 3,062,000 | 7.11% | ||
| 6 | PUTNAM INVESTMENTS LLC | 351,000 | 2,913,000 | 6.77% | ||
| 7 | ACUTA CAPITAL PARTNERS, LLC | 320,555 | 2,661,000 | 6.18% | ||
| 8 | Rathbones Group PLC | 327,246 | 2,543,000 | 5.91% | ||
| 9 | C WorldWide Group Holding A/S | 295,184 | 2,450,000 | 5.69% | ||
| 10 | Fortress Investment Group LLC | 277,777 | 2,306,000 | 5.36% | ||
| 11 | JENNISON ASSOCIATES LLC | 277,439 | 2,303,000 | 5.35% | ||
| 12 | Alyeska Investment Group, L.P. | 210,972 | 1,751,000 | 4.07% | ||
| 13 | ELLIOTT MANAGEMENT CORP | 170,391 | 1,414,000 | 3.29% | ||
| 14 | Bank of New York Mellon Corp | 52,914 | 439,000 | 1.02% | ||
| 15 | UBS Group AG | 18,209 | 151,000 | 0.35% | ||
| 16 | PARTNERS CAPITAL INVESTMENT GROUP (HOLDINGS), LLC | 17,526 | 145,000 | 0.34% | ||
| 17 | Fiduciary Trust Co International of Pennsylvania | 15,725 | 131,000 | 0.30% | ||
| 18 | HOWLAND CAPITAL MANAGEMENT LLC | 10,000 | 83,000 | 0.19% | ||
| 19 | CITIGROUP INC | 2,000 | 17,000 | 0.04% | ||
| 20 | Tower Research Capital LLC (TRC) | 726 | 6,000 | 0.01% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
