| # | % | |||||
|---|---|---|---|---|---|---|
| 51 | BRIDGEWAY CAPITAL MANAGEMENT, LLC | 80,000 | 648,000 | 0.31% | ||
| 52 | Bank of New York Mellon Corp | 80,201 | 649,000 | 0.31% | ||
| 53 | HANDELSBANKEN FONDER AB | 95,000 | 770,000 | 0.37% | ||
| 54 | Iguana Healthcare Management, LLC | 100,000 | 810,000 | 0.39% | ||
| 55 | DAFNA Capital Management LLC | 101,317 | 821,000 | 0.39% | ||
| 56 | GEODE CAPITAL MANAGEMENT, LLC | 137,443 | 1,113,000 | 0.53% | ||
| 57 | PNC FINANCIAL SERVICES GROUP, INC. | 205,083 | 1,660,000 | 0.80% | ||
| 58 | NORTHERN TRUST CORP | 233,451 | 1,891,000 | 0.91% | ||
| 59 | Artal Group S.A. | 251,300 | 2,036,000 | 0.98% | ||
| 60 | STATE STREET CORP | 299,947 | 2,429,000 | 1.16% | ||
| 61 | MARSHALL WACE NORTH AMERICA, L.P. | 432,171 | 3,457,000 | 1.66% | ||
| 62 | MARSHALL WACE ASIA LTD | 432,171 | 3,457,000 | 1.66% | ||
| 63 | PRICE T ROWE ASSOCIATES INC /MD/ | 609,344 | 4,936,000 | 2.36% | ||
| 64 | ORBIMED ADVISORS LLC | 704,300 | 5,705,000 | 2.73% | ||
| 65 | NEXTHERA CAPITAL LP | 757,200 | 6,133,000 | 2.94% | ||
| 66 | PERCEPTIVE ADVISORS LLC | 810,537 | 6,565,000 | 3.14% | ||
| 67 | FRANKLIN RESOURCES INC | 833,100 | 6,748,000 | 3.23% | ||
| 68 | VANGUARD GROUP INC | 939,297 | 7,608,000 | 3.64% | ||
| 69 | BlackRock Finance, Inc. | 1,518,325 | 12,298,000 | 5.89% | ||
| 70 | Cormorant Asset Management, LP | 2,307,903 | 18,694,000 | 8.95% | ||
| 71 | HIGHLAND CAPITAL MANAGEMENT LP | 2,440,521 | 19,768,000 | 9.47% | ||
| 72 | FMR LLC | 4,980,794 | 40,344,000 | 19.32% | ||
| 73 | FEDERATED HERMES, INC. | 6,372,923 | 51,621,000 | 24.72% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
