| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | INCYTE | 23,498,697 | 1,879,426,000 | 19.70% | ||
| 2 | SEATTLE GENETICS INC | 43,238,967 | 1,747,287,000 | 18.32% | ||
| 3 | ABBVIE INC | 14,373,538 | 889,866,000 | 9.33% | ||
| 4 | ACADIA PHARMACEUTICALS INC COM | 24,516,738 | 795,813,000 | 8.34% | ||
| 5 | ALEXION PHARMACEUTIC | 6,543,295 | 763,995,000 | 8.01% | ||
| 6 | Incyte Corporation | 274,500,000 | 467,293,000 | 4.90% | PRN | |
| 7 | Incyte Corporation | 259,000,000 | 431,835,000 | 4.53% | PRN | |
| 8 | BIOMARIN | 4,806,483 | 373,944,000 | 3.92% | ||
| 9 | GENOMIC HEALTH INC COM | 13,668,866 | 353,955,000 | 3.71% | ||
| 10 | DBV TECHNOLOGIES | 5,509,560 | 179,722,000 | 1.88% | ||
| 11 | XENOPORT INC | 100,000,000 | 98,471,000 | 1.03% | PRN | |
| 12 | ACORDA THERAPEUTICS | 3,661,082 | 93,376,000 | 0.98% | ||
| 13 | BIOMARIN PHARMACEUTICAL INC | 22,379,000 | 84,908,000 | 0.89% | PRN | |
| 14 | CERUS CORP | 13,553,275 | 84,572,000 | 0.89% | ||
| 15 | SPARK THERAPEUTICS INC | 1,318,341 | 67,407,000 | 0.71% | ||
| 16 | ACORDA THERAPEUTICS INC | 77,083,000 | 67,351,000 | 0.71% | PRN | |
| 17 | BELLICUM PHARMACEUTICALS INC COM | 4,865,647 | 63,059,000 | 0.66% | ||
| 18 | BEIGENE LTD | 1,912,680 | 56,998,000 | 0.60% | ||
| 19 | HERON THERAPEUTICS INC | 2,857,250 | 51,573,000 | 0.54% | ||
| 20 | Aquinox Pharmaceuticals Inc | 7,752,487 | 51,321,000 | 0.54% | ||
| 21 | CLOVIS ONCOLOGY INC NOTE | 72,758,000 | 51,310,000 | 0.54% | PRN | |
| 22 | INVITAE CORP | 6,554,967 | 48,441,000 | 0.51% | ||
| 23 | BIOCRYST PHARMACEUTICALS | 15,010,534 | 42,630,000 | 0.45% | ||
| 24 | NEUROCRINE BIOSCIE COM USD0.001 | 895,422 | 40,697,000 | 0.43% | ||
| 25 | VERSARTIS INC COM | 2,723,399 | 30,121,000 | 0.32% | ||
| 26 | Exelexis | 20,000,000 | 29,654,000 | 0.31% | PRN | |
| 27 | ADVANCED ACCELERATOR APPLIC | 833,089 | 25,188,000 | 0.26% | ||
| 28 | XENOPORT INC | 3,475,672 | 24,469,000 | 0.26% | ||
| 29 | INTRA CELLULAR THERAPIES INC COM | 609,166 | 23,648,000 | 0.25% | ||
| 30 | SANGAMO BIOSCIENCES INCORPORATED | 4,055,876 | 23,484,000 | 0.25% | ||
| 31 | INTELLIA THERAPEUTICS INC | 1,062,120 | 22,676,000 | 0.24% | ||
| 32 | EXELIXIS INC | 2,580,000 | 20,150,000 | 0.21% | ||
| 33 | MEDIVATION INC | 329,876 | 19,892,000 | 0.21% | ||
| 34 | ACHILLION PHARMACEUTICALS INC COM | 2,475,515 | 19,309,000 | 0.20% | ||
| 35 | NOVAVAX INC COM | 2,379,254 | 17,297,000 | 0.18% | ||
| 36 | PROGENICS PHARMACEUTICALS IN | 3,970,250 | 16,754,000 | 0.18% | ||
| 37 | XENCOR INC COM | 872,072 | 16,561,000 | 0.17% | ||
| 38 | HALOZYME THERAPEUTICS INC | 1,838,057 | 15,862,000 | 0.17% | ||
| 39 | ARRAY BIOPHARMA INC COM | 4,310,666 | 15,346,000 | 0.16% | ||
| 40 | CORSICANTO LTD | 15,000,000 | 15,285,000 | 0.16% | PRN | |
| 41 | AEGERION PHARMACEUTICALS INC | 26,517,000 | 14,840,000 | 0.16% | PRN | |
| 42 | INSMED INC COM PAR .01 | 1,500,000 | 14,790,000 | 0.16% | ||
| 43 | DERMA SCIENCES INC COM PAR .01 | 3,752,390 | 14,784,000 | 0.16% | ||
| 44 | GALAPAGOS NV | 259,894 | 14,416,000 | 0.15% | ||
| 45 | Foamix Pharmaceuticals Ltd. | 2,241,702 | 14,235,000 | 0.15% | ||
| 46 | BIOMARIN PHARMACEUTICAL INC | 12,228,000 | 13,573,000 | 0.14% | PRN | |
| 47 | BLUEBIRD BIO INCORPORATED | 293,943 | 12,725,000 | 0.13% | ||
| 48 | MIRATI THERAPEUTICS INC COM | 2,269,198 | 12,390,000 | 0.13% | ||
| 49 | TG THERAPEUTICS INC COM | 2,003,991 | 12,144,000 | 0.13% | ||
| 50 | ALKERMES PLC SHS | 250,251 | 10,816,000 | 0.11% |
Portfolio data is normalized using SEC Form 13F filings, including the Original 13F-HR (0001144204-16-119409, filed 2016.08.15).
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
