| 1 |
QVT Financial LP |
3,873,000 |
4,540,000 |
34.65% |
|
|
| 2 |
BVF INC/IL |
2,809,824 |
3,456,000 |
26.38% |
|
|
| 3 |
DEERFIELD MANAGEMENT COMPANY, L.P. |
2,000,000 |
2,460,000 |
18.78% |
|
|
| 4 |
VANGUARD GROUP INC |
1,406,530 |
1,730,000 |
13.20% |
|
|
| 5 |
BlackRock Institutional Trust Company, N.A. |
244,595 |
301,000 |
2.30% |
|
|
| 6 |
GEODE CAPITAL MANAGEMENT, LLC |
116,629 |
143,000 |
1.09% |
|
|
| 7 |
DEUTSCHE BANK AG\ |
48,700 |
59,000 |
0.45% |
|
|
| 8 |
NORTHERN TRUST CORP |
46,730 |
58,000 |
0.44% |
|
|
| 9 |
Rotella Capital Management, Inc. |
40,500 |
51,000 |
0.39% |
|
|
| 10 |
CALIFORNIA PUBLIC EMPLOYEES RETIREMENT SYSTEM |
40,602 |
50,000 |
0.38% |
|
|
| 11 |
ROYCE & ASSOCIATES LP |
35,000 |
43,000 |
0.33% |
|
|
| 12 |
WealthTrust Axiom LLC |
31,135 |
38,000 |
0.29% |
|
|
| 13 |
Essex Woodlands Management, Inc. |
23,928 |
29,000 |
0.22% |
|
|
| 14 |
STATE STREET CORP |
19,510 |
24,000 |
0.18% |
|
|
| 15 |
PALISADE CAPITAL MANAGEMENT, LP |
19,010 |
23,000 |
0.18% |
|
|
| 16 |
BLACKROCK ADVISORS LLC |
16,279 |
20,000 |
0.15% |
|
|
| 17 |
GUGGENHEIM CAPITAL LLC |
13,906 |
17,000 |
0.13% |
|
|
| 18 |
Baystate Wealth Management LLC |
13,233 |
16,000 |
0.12% |
|
|
| 19 |
BANK OF AMERICA CORP /DE/ |
11,850 |
14,000 |
0.11% |
|
|
| 20 |
B. Riley Wealth Advisors, Inc. |
10,000 |
12,000 |
0.09% |
|
|
| 21 |
WELLS FARGO & COMPANY/MN |
6,000 |
7,000 |
0.05% |
|
|
| 22 |
UBS AG |
4,767 |
5,000 |
0.04% |
|
|
| 23 |
US BANCORP \DE\ |
3,000 |
4,000 |
0.03% |
|
|
| 24 |
NEW ENGLAND SECURITIES CORP /MA/ |
1,000 |
1,000 |
0.01% |
|
|
| 25 |
CT Financial Advisors LLC |
375 |
383 |
0.00% |
|
|
| 26 |
AMERICAN INTERNATIONAL GROUP, INC. |
40 |
49 |
0.00% |
|
|
| 27 |
ROYAL BANK OF CANADA |
1 |
0 |
0.00% |
|
|
| 28 |
Barrett Asset Management, LLC |
100 |
0 |
0.00% |
|
|
| 29 |
LADENBURG THALMANN FINANCIAL SERVICES INC. |
140 |
0 |
0.00% |
|
|
| 30 |
WealthTrust-Arizona, LLC |
200 |
0 |
0.00% |
|
|
| 31 |
MORGAN STANLEY |
294 |
0 |
0.00% |
|
|
| 32 |
FIRST MANHATTAN CO. LLC. |
50 |
0 |
0.00% |
|
|
| 33 |
Creative Planning |
50 |
0 |
0.00% |
|
|
