| 1 |
QVT Financial LP |
3,495,336 |
3,062,000 |
33.90% |
|
|
| 2 |
DEERFIELD MANAGEMENT COMPANY, L.P. |
2,000,000 |
1,860,000 |
20.59% |
|
|
| 3 |
VANGUARD GROUP INC |
1,461,391 |
1,359,000 |
15.05% |
|
|
| 4 |
SPHERA FUNDS MANAGEMENT LTD. |
1,084,466 |
1,009,000 |
11.17% |
|
|
| 5 |
BVF INC/IL |
750,655 |
698,000 |
7.73% |
|
|
| 6 |
BlackRock Institutional Trust Company, N.A. |
436,407 |
406,000 |
4.50% |
|
|
| 7 |
CALIFORNIA PUBLIC EMPLOYEES RETIREMENT SYSTEM |
193,102 |
180,000 |
1.99% |
|
|
| 8 |
GEODE CAPITAL MANAGEMENT, LLC |
129,598 |
120,000 |
1.33% |
|
|
| 9 |
DEUTSCHE BANK AG\ |
48,700 |
45,000 |
0.50% |
|
|
| 10 |
NORTHERN TRUST CORP |
46,730 |
44,000 |
0.49% |
|
|
| 11 |
ROYCE & ASSOCIATES LP |
35,000 |
33,000 |
0.37% |
|
|
| 12 |
WealthTrust Axiom LLC |
31,535 |
29,000 |
0.32% |
|
|
| 13 |
Rotella Capital Management, Inc. |
29,151 |
27,000 |
0.30% |
|
|
| 14 |
Essex Woodlands Management, Inc. |
23,928 |
23,000 |
0.25% |
|
|
| 15 |
STATE STREET CORP |
19,510 |
18,000 |
0.20% |
|
|
| 16 |
PALISADE CAPITAL MANAGEMENT, LP |
19,010 |
18,000 |
0.20% |
|
|
| 17 |
UBS AG |
16,165 |
15,000 |
0.17% |
|
|
| 18 |
BLACKROCK ADVISORS LLC |
16,279 |
15,000 |
0.17% |
|
|
| 19 |
PNC FINANCIAL SERVICES GROUP, INC. |
15,000 |
14,000 |
0.16% |
|
|
| 20 |
Baystate Wealth Management LLC |
13,233 |
12,000 |
0.13% |
|
|
| 21 |
BANK OF AMERICA CORP /DE/ |
11,877 |
11,000 |
0.12% |
|
|
| 22 |
CREDIT SUISSE AG/ |
10,237 |
10,000 |
0.11% |
|
|
| 23 |
B. Riley Wealth Advisors, Inc. |
10,000 |
9,000 |
0.10% |
|
|
| 24 |
BlackRock Investment Management, LLC |
6,591 |
6,000 |
0.07% |
|
|
| 25 |
WELLS FARGO & COMPANY/MN |
6,000 |
6,000 |
0.07% |
|
|
| 26 |
US BANCORP \DE\ |
3,000 |
3,000 |
0.03% |
|
|
| 27 |
AMERICAN INTERNATIONAL GROUP, INC. |
40 |
37 |
0.00% |
|
|
| 28 |
FIRST MANHATTAN CO. LLC. |
50 |
0 |
0.00% |
|
|
| 29 |
WealthTrust-Arizona, LLC |
200 |
0 |
0.00% |
|
|
| 30 |
Creative Planning |
50 |
0 |
0.00% |
|
|
| 31 |
MORGAN STANLEY |
100 |
0 |
0.00% |
|
|
| 32 |
LADENBURG THALMANN FINANCIAL SERVICES INC. |
140 |
0 |
0.00% |
|
|
