| 1 |
QVT Financial LP |
3,873,000 |
3,654,000 |
37.59% |
|
|
| 2 |
DEERFIELD MANAGEMENT COMPANY, L.P. |
2,000,000 |
1,980,000 |
20.37% |
|
|
| 3 |
BVF INC/IL |
1,610,652 |
1,595,000 |
16.41% |
|
|
| 4 |
VANGUARD GROUP INC |
1,430,530 |
1,416,000 |
14.56% |
|
|
| 5 |
BlackRock Institutional Trust Company, N.A. |
377,994 |
374,000 |
3.85% |
|
|
| 6 |
CALIFORNIA PUBLIC EMPLOYEES RETIREMENT SYSTEM |
193,102 |
191,000 |
1.96% |
|
|
| 7 |
GEODE CAPITAL MANAGEMENT, LLC |
116,629 |
115,000 |
1.18% |
|
|
| 8 |
Rotella Capital Management, Inc. |
70,544 |
72,000 |
0.74% |
|
|
| 9 |
DEUTSCHE BANK AG\ |
48,700 |
48,000 |
0.49% |
|
|
| 10 |
NORTHERN TRUST CORP |
46,730 |
47,000 |
0.48% |
|
|
| 11 |
ROYCE & ASSOCIATES LP |
35,000 |
35,000 |
0.36% |
|
|
| 12 |
WealthTrust Axiom LLC |
31,135 |
30,000 |
0.31% |
|
|
| 13 |
Essex Woodlands Management, Inc. |
23,928 |
24,000 |
0.25% |
|
|
| 14 |
UBS AG |
21,563 |
22,000 |
0.23% |
|
|
| 15 |
STATE STREET CORP |
19,510 |
19,000 |
0.20% |
|
|
| 16 |
PALISADE CAPITAL MANAGEMENT, LP |
19,010 |
19,000 |
0.20% |
|
|
| 17 |
BLACKROCK ADVISORS LLC |
16,279 |
16,000 |
0.16% |
|
|
| 18 |
Baystate Wealth Management LLC |
13,233 |
13,000 |
0.13% |
|
|
| 19 |
GUGGENHEIM CAPITAL LLC |
12,642 |
13,000 |
0.13% |
|
|
| 20 |
BANK OF AMERICA CORP /DE/ |
11,850 |
12,000 |
0.12% |
|
|
| 21 |
B. Riley Wealth Advisors, Inc. |
10,000 |
9,900 |
0.10% |
|
|
| 22 |
BlackRock Investment Management, LLC |
6,591 |
7,000 |
0.07% |
|
|
| 23 |
WELLS FARGO & COMPANY/MN |
6,000 |
6,000 |
0.06% |
|
|
| 24 |
US BANCORP \DE\ |
3,000 |
3,000 |
0.03% |
|
|
| 25 |
NEW ENGLAND SECURITIES CORP /MA/ |
1,000 |
1,000 |
0.01% |
|
|
| 26 |
AMERICAN INTERNATIONAL GROUP, INC. |
40 |
40 |
0.00% |
|
|
| 27 |
WealthTrust-Arizona, LLC |
200 |
0 |
0.00% |
|
|
| 28 |
FIRST MANHATTAN CO. LLC. |
50 |
0 |
0.00% |
|
|
| 29 |
Creative Planning |
50 |
0 |
0.00% |
|
|
| 30 |
MORGAN STANLEY |
100 |
0 |
0.00% |
|
|
| 31 |
LADENBURG THALMANN FINANCIAL SERVICES INC. |
140 |
0 |
0.00% |
|
|
