| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | WELLINGTON MANAGEMENT GROUP LLP | 4,258,749 | 20,485,000 | 32.67% | ||
| 2 | ORBIMED ADVISORS LLC | 2,821,500 | 13,571,000 | 21.64% | ||
| 3 | RENAISSANCE TECHNOLOGIES LLC | 1,266,000 | 6,089,000 | 9.71% | ||
| 4 | Pine River Capital Management L.P. | 1,095,041 | 5,267,000 | 8.40% | ||
| 5 | FIL Ltd | 949,300 | 4,566,000 | 7.28% | ||
| 6 | BlackRock Fund Advisors | 679,613 | 3,269,000 | 5.21% | ||
| 7 | PICTET ASSET MANAGEMENT LTD | 266,900 | 1,284,000 | 2.05% | ||
| 8 | Invesco Ltd. | 201,135 | 967,000 | 1.54% | ||
| 9 | MORGAN STANLEY | 177,301 | 853,000 | 1.36% | ||
| 10 | GOLDMAN SACHS GROUP INC | 162,214 | 780,000 | 1.24% | ||
| 11 | CITADEL ADVISORS LLC | 157,038 | 755,000 | 1.20% | ||
| 12 | DEUTSCHE BANK AG\ | 149,099 | 716,000 | 1.14% | ||
| 13 | TWO SIGMA INVESTMENTS, LP | 103,697 | 499,000 | 0.80% | ||
| 14 | TWO SIGMA ADVISERS, LP | 94,300 | 454,000 | 0.72% | ||
| 15 | TFS CAPITAL LLC | 89,178 | 429,000 | 0.68% | ||
| 16 | CALIFORNIA PUBLIC EMPLOYEES RETIREMENT SYSTEM | 76,001 | 366,000 | 0.58% | ||
| 17 | COMMONWEALTH BANK OF AUSTRALIA | 74,404 | 358,000 | 0.57% | ||
| 18 | GSA CAPITAL PARTNERS LLP | 64,800 | 312,000 | 0.50% | ||
| 19 | MILLENNIUM MANAGEMENT LLC | 41,408 | 199,000 | 0.32% | ||
| 20 | A.R.T. Advisors, LLC | 41,132 | 197,000 | 0.31% | ||
| 21 | ProShare Advisors LLC | 28,632 | 138,000 | 0.22% | ||
| 22 | BlackRock Institutional Trust Company, N.A. | 26,893 | 129,000 | 0.21% | ||
| 23 | STEVENS CAPITAL MANAGEMENT LP | 22,385 | 108,000 | 0.17% | ||
| 24 | Freedom Investment Management, Inc. | 21,758 | 105,000 | 0.17% | ||
| 25 | ClariVest Asset Management LLC | 19,726 | 95,000 | 0.15% | ||
| 26 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 15,441 | 74,000 | 0.12% | ||
| 27 | Virtu KCG Holdings LLC | 13,526 | 65,000 | 0.10% | ||
| 28 | Verition Fund Management LLC | 13,512 | 65,000 | 0.10% | ||
| 29 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 12,000 | 58,000 | 0.09% | Put | |
| 30 | GEODE CAPITAL MANAGEMENT, LLC | 11,180 | 53,000 | 0.08% | ||
| 31 | CREDIT SUISSE AG/ | 10,756 | 51,000 | 0.08% | ||
| 32 | BANK OF AMERICA CORP /DE/ | 10,301 | 50,000 | 0.08% | ||
| 33 | Airain ltd | 10,265 | 49,000 | 0.08% | ||
| 34 | Tower Research Capital LLC (TRC) | 8,771 | 42,000 | 0.07% | ||
| 35 | GROUP ONE TRADING LLC | 6,695 | 32,000 | 0.05% | ||
| 36 | CITIGROUP INC | 6,656 | 32,000 | 0.05% | ||
| 37 | UBS AG | 6,509 | 31,000 | 0.05% | ||
| 38 | AMERICAN INTERNATIONAL GROUP, INC. | 5,100 | 24,531 | 0.04% | ||
| 39 | WELLS FARGO & COMPANY/MN | 4,830 | 24,000 | 0.04% | ||
| 40 | PNC FINANCIAL SERVICES GROUP, INC. | 5,000 | 24,000 | 0.04% | ||
| 41 | BARCLAYS PLC | 5,400 | 22,000 | 0.04% | ||
| 42 | BANK OF MONTREAL /CAN/ | 2,000 | 10,000 | 0.02% | ||
| 43 | Creative Planning | 1,000 | 5,000 | 0.01% | ||
| 44 | MSI Financial Services Inc | 1,000 | 5,000 | 0.01% | ||
| 45 | UBS AG | 200 | 1,000 | 0.00% | Call | |
| 46 | Apriem Advisors | 300 | 1,000 | 0.00% | ||
| 47 | WFG Advisors, LP | 200 | 1,000 | 0.00% | ||
| 48 | Ground Swell Capital, LLC | 145 | 1,000 | 0.00% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
