| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | WELLINGTON MANAGEMENT GROUP LLP | 4,389,060 | 22,954,000 | 33.88% | ||
| 2 | ORBIMED ADVISORS LLC | 2,821,500 | 14,756,000 | 21.78% | ||
| 3 | RENAISSANCE TECHNOLOGIES LLC | 1,176,362 | 6,152,000 | 9.08% | ||
| 4 | Pine River Capital Management L.P. | 1,095,041 | 5,727,000 | 8.45% | ||
| 5 | FIL Ltd | 1,065,301 | 5,572,000 | 8.22% | ||
| 6 | BlackRock Fund Advisors | 661,735 | 3,461,000 | 5.11% | ||
| 7 | PICTET ASSET MANAGEMENT LTD | 305,900 | 1,600,000 | 2.36% | ||
| 8 | DEUTSCHE BANK AG\ | 157,983 | 825,000 | 1.22% | ||
| 9 | CITADEL ADVISORS LLC | 156,237 | 817,000 | 1.21% | ||
| 10 | Invesco Ltd. | 143,732 | 752,000 | 1.11% | ||
| 11 | GOLDMAN SACHS GROUP INC | 130,123 | 681,000 | 1.01% | ||
| 12 | MORGAN STANLEY | 116,679 | 610,000 | 0.90% | ||
| 13 | TWO SIGMA INVESTMENTS, LP | 84,888 | 444,000 | 0.66% | ||
| 14 | TWO SIGMA ADVISERS, LP | 82,200 | 430,000 | 0.63% | ||
| 15 | COMMONWEALTH BANK OF AUSTRALIA | 77,452 | 405,000 | 0.60% | ||
| 16 | Sensato Investors LLC | 75,772 | 396,000 | 0.58% | ||
| 17 | CALIFORNIA PUBLIC EMPLOYEES RETIREMENT SYSTEM | 75,900 | 367,000 | 0.54% | ||
| 18 | Freedom Investment Management, Inc. | 56,519 | 296,000 | 0.44% | ||
| 19 | ProShare Advisors LLC | 36,802 | 192,000 | 0.28% | ||
| 20 | MILLENNIUM MANAGEMENT LLC | 31,700 | 166,000 | 0.25% | ||
| 21 | BlackRock Institutional Trust Company, N.A. | 24,460 | 128,000 | 0.19% | ||
| 22 | CREDIT SUISSE AG/ | 19,926 | 104,000 | 0.15% | ||
| 23 | ClariVest Asset Management LLC | 19,726 | 103,000 | 0.15% | ||
| 24 | STEVENS CAPITAL MANAGEMENT LP | 17,821 | 93,000 | 0.14% | ||
| 25 | GEODE CAPITAL MANAGEMENT, LLC | 17,025 | 89,000 | 0.13% | ||
| 26 | A.R.T. Advisors, LLC | 15,562 | 81,000 | 0.12% | ||
| 27 | GROUP ONE TRADING LLC | 14,927 | 78,000 | 0.12% | ||
| 28 | Verition Fund Management LLC | 14,413 | 75,000 | 0.11% | ||
| 29 | GSA CAPITAL PARTNERS LLP | 13,186 | 69,000 | 0.10% | ||
| 30 | CITIGROUP INC | 11,624 | 61,000 | 0.09% | ||
| 31 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 10,897 | 57,000 | 0.08% | ||
| 32 | TFS CAPITAL LLC | 10,881 | 57,000 | 0.08% | ||
| 33 | UBS Group AG | 8,865 | 46,000 | 0.07% | ||
| 34 | WELLS FARGO & COMPANY/MN | 5,330 | 28,000 | 0.04% | ||
| 35 | AMERICAN INTERNATIONAL GROUP, INC. | 4,600 | 24,058 | 0.04% | ||
| 36 | BARCLAYS PLC | 3,700 | 19,000 | 0.03% | ||
| 37 | STANCORP INVESTMENT ADVISERS INC | 1,637 | 9,000 | 0.01% | ||
| 38 | US BANCORP \DE\ | 1,500 | 8,000 | 0.01% | ||
| 39 | MSI Financial Services Inc | 1,000 | 5,000 | 0.01% | ||
| 40 | Tower Research Capital LLC (TRC) | 931 | 5,000 | 0.01% | ||
| 41 | Creative Planning | 500 | 3,000 | 0.00% | ||
| 42 | BANK OF AMERICA CORP /DE/ | 521 | 3,000 | 0.00% | ||
| 43 | LADENBURG THALMANN FINANCIAL SERVICES INC. | 300 | 2,000 | 0.00% | ||
| 44 | WFG Advisors, LP | 200 | 1,000 | 0.00% | ||
| 45 | UBS Group AG | 200 | 1,000 | 0.00% | Call |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
