| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | ORBIMED ADVISORS LLC | 2,180,000 | 82,273,000 | 8.41% | ||
| 2 | Meritech Capital Associates III L.L.C. | 2,098,624 | 79,202,000 | 8.09% | ||
| 3 | LORD, ABBETT & CO. LLC | 1,812,419 | 68,401,000 | 6.99% | ||
| 4 | Capital World Investors | 1,706,070 | 64,387,000 | 6.58% | ||
| 5 | GILDER GAGNON HOWE & CO LLC | 1,612,194 | 60,844,000 | 6.22% | ||
| 6 | VANGUARD GROUP INC | 1,150,367 | 43,416,000 | 4.44% | ||
| 7 | WILLIAM BLAIR INVESTMENT MANAGEMENT, LLC | 1,075,860 | 40,603,000 | 4.15% | ||
| 8 | FEDERATED HERMES, INC. | 982,990 | 37,098,000 | 3.79% | ||
| 9 | NEXT CENTURY GROWTH INVESTORS LLC | 861,409 | 32,509,000 | 3.32% | ||
| 10 | ALLIANCEBERNSTEIN L.P. | 787,625 | 29,725,000 | 3.04% | ||
| 11 | WELLINGTON MANAGEMENT GROUP LLP | 784,027 | 29,589,000 | 3.02% | ||
| 12 | RENAISSANCE TECHNOLOGIES LLC | 705,200 | 26,614,000 | 2.72% | ||
| 13 | WELLS FARGO & COMPANY/MN | 638,685 | 24,104,000 | 2.46% | ||
| 14 | DEERFIELD MANAGEMENT COMPANY, L.P. | 503,277 | 18,994,000 | 1.94% | ||
| 15 | BlackRock Fund Advisors | 421,164 | 15,895,000 | 1.62% | ||
| 16 | BANK OF AMERICA CORP /DE/ | 397,407 | 14,998,000 | 1.53% | ||
| 17 | BlackRock Institutional Trust Company, N.A. | 393,110 | 14,836,000 | 1.52% | ||
| 18 | C WorldWide Group Holding A/S | 340,000 | 12,832,000 | 1.31% | ||
| 19 | CITADEL ADVISORS LLC | 314,492 | 11,869,000 | 1.21% | ||
| 20 | TWO SIGMA INVESTMENTS, LP | 299,461 | 11,302,000 | 1.15% | ||
| 21 | FULLER & THALER ASSET MANAGEMENT, INC. | 288,580 | 10,891,000 | 1.11% | ||
| 22 | JANUS HENDERSON INVESTORS US LLC | 266,515 | 10,058,000 | 1.03% | ||
| 23 | STATE STREET CORP | 263,224 | 9,934,000 | 1.01% | ||
| 24 | JPMORGAN CHASE & CO | 258,512 | 9,756,000 | 1.00% | ||
| 25 | Numeric Investors LLC | 257,180 | 9,706,000 | 0.99% | ||
| 26 | NORTHERN TRUST CORP | 247,036 | 9,323,000 | 0.95% | ||
| 27 | EverPoint Asset Management, LLC | 235,000 | 8,869,000 | 0.91% | ||
| 28 | Jupiter Investment Management Ltd | 189,984 | 7,169,000 | 0.73% | ||
| 29 | Cortina Asset Management, LLC | 182,458 | 6,886,000 | 0.70% | ||
| 30 | MAGEE THOMSON INVESTMENT PARTNERS LLC | 152,737 | 5,763,000 | 0.59% | ||
| 31 | TWO SIGMA ADVISERS, LP | 152,400 | 5,752,000 | 0.59% | ||
| 32 | Point72 Asset Management, L.P. | 142,600 | 5,382,000 | 0.55% | ||
| 33 | Employees Retirement System of Texas | 134,000 | 5,057,000 | 0.52% | ||
| 34 | MORGAN STANLEY | 133,983 | 5,056,000 | 0.52% | ||
| 35 | AMERICAN CENTURY COMPANIES INC | 132,239 | 4,991,000 | 0.51% | ||
| 36 | TIAA CREF INVESTMENT MANAGEMENT LLC | 131,263 | 4,954,000 | 0.51% | ||
| 37 | Atika Capital Management LLC | 128,400 | 4,846,000 | 0.50% | ||
| 38 | HANDELSBANKEN FONDER AB | 125,000 | 4,718,000 | 0.48% | ||
| 39 | Artisan Partners Limited Partnership | 124,736 | 4,708,000 | 0.48% | ||
| 40 | DEUTSCHE BANK AG\ | 124,299 | 4,690,000 | 0.48% | ||
| 41 | GOLDMAN SACHS GROUP INC | 120,913 | 4,563,000 | 0.47% | ||
| 42 | EMERALD ACQUISITION LTD. | 120,701 | 4,555,000 | 0.47% | ||
| 43 | Iguana Healthcare Management, LLC | 120,000 | 4,529,000 | 0.46% | ||
| 44 | OBERWEIS ASSET MANAGEMENT INC/ | 116,060 | 4,380,000 | 0.45% | ||
| 45 | BAMCO INC /NY/ | 115,261 | 4,350,000 | 0.44% | ||
| 46 | AMERIPRISE FINANCIAL INC | 114,026 | 4,304,000 | 0.44% | ||
| 47 | Bank of New York Mellon Corp | 101,528 | 3,832,000 | 0.39% | ||
| 48 | HAMILTON LANE ADVISORS LLC | 98,370 | 3,712,000 | 0.38% | ||
| 49 | Calvert Investment Management, Inc. | 97,705 | 3,687,000 | 0.38% | ||
| 50 | HBK INVESTMENTS L P | 92,365 | 3,486,000 | 0.36% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
