| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | DEERFIELD MANAGEMENT COMPANY, L.P. | 1,420,497 | 20,597,000 | 19.30% | ||
| 2 | Arete Wealth Advisors, LLC | 1,044,344 | 15,143,000 | 14.19% | ||
| 3 | DSC Advisors, L.P. | 893,558 | 12,957,000 | 12.14% | ||
| 4 | Alyeska Investment Group, L.P. | 414,893 | 6,016,000 | 5.64% | ||
| 5 | SCHRODER INVESTMENT MANAGEMENT GROUP | 342,700 | 5,137,000 | 4.81% | ||
| 6 | Point72 Asset Management, L.P. | 318,076 | 4,612,000 | 4.32% | ||
| 7 | VANGUARD GROUP INC | 307,820 | 4,463,000 | 4.18% | ||
| 8 | Broadfin Capital, LLC | 299,695 | 4,346,000 | 4.07% | ||
| 9 | DRIEHAUS CAPITAL MANAGEMENT LLC | 244,811 | 3,550,000 | 3.33% | ||
| 10 | KINGDON CAPITAL MANAGEMENT, L.L.C. | 238,224 | 3,454,000 | 3.24% | ||
| 11 | BlackRock Fund Advisors | 201,772 | 2,926,000 | 2.74% | ||
| 12 | FEDERATED HERMES, INC. | 200,000 | 2,900,000 | 2.72% | ||
| 13 | SPHERA FUNDS MANAGEMENT LTD. | 183,954 | 2,667,000 | 2.50% | ||
| 14 | Endurant Capital Management LP | 169,586 | 2,459,000 | 2.30% | ||
| 15 | C WorldWide Group Holding A/S | 165,000 | 2,392,000 | 2.24% | ||
| 16 | GOLDMAN SACHS GROUP INC | 85,753 | 1,243,000 | 1.16% | ||
| 17 | WELLINGTON MANAGEMENT GROUP LLP | 62,892 | 912,000 | 0.85% | ||
| 18 | KENNEDY CAPITAL MANAGEMENT LLC | 55,126 | 799,000 | 0.75% | ||
| 19 | COWEN INC. | 54,435 | 789,000 | 0.74% | ||
| 20 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 49,311 | 715,000 | 0.67% | ||
| 21 | Spark Investment Management LLC | 47,825 | 693,000 | 0.65% | ||
| 22 | MOORE CAPITAL MANAGEMENT, LP | 41,000 | 595,000 | 0.56% | ||
| 23 | BlackRock Group LTD | 40,903 | 593,000 | 0.56% | ||
| 24 | BlackRock Institutional Trust Company, N.A. | 35,485 | 515,000 | 0.48% | ||
| 25 | CREDIT SUISSE AG/ | 34,472 | 500,000 | 0.47% | ||
| 26 | GEODE CAPITAL MANAGEMENT, LLC | 34,435 | 499,000 | 0.47% | ||
| 27 | TFS CAPITAL LLC | 32,862 | 476,000 | 0.45% | ||
| 28 | Boyle Capital Management, L.L.C. | 28,957 | 420,000 | 0.39% | ||
| 29 | UBS Group AG | 27,176 | 394,000 | 0.37% | ||
| 30 | MILLENNIUM MANAGEMENT LLC | 23,296 | 338,000 | 0.32% | ||
| 31 | JPMORGAN CHASE & CO | 21,163 | 307,000 | 0.29% | ||
| 32 | Iowa State Bank | 19,020 | 276,000 | 0.26% | ||
| 33 | NORTHERN TRUST CORP | 18,914 | 274,000 | 0.26% | ||
| 34 | Evanson Asset Management, LLC | 17,094 | 248,000 | 0.23% | ||
| 35 | Segantii Capital Management Ltd | 16,100 | 241,000 | 0.23% | ||
| 36 | WILLIAM HARRIS INVESTORS INC | 15,980 | 232,000 | 0.22% | ||
| 37 | A.R.T. Advisors, LLC | 13,659 | 198,000 | 0.19% | ||
| 38 | MORGAN STANLEY | 12,646 | 183,000 | 0.17% | ||
| 39 | DEUTSCHE BANK AG\ | 11,917 | 172,000 | 0.16% | ||
| 40 | NOMURA HOLDINGS INC | 11,730 | 170,000 | 0.16% | ||
| 41 | MENTA CAPITAL LLC | 11,410 | 165,000 | 0.15% | ||
| 42 | ProShare Advisors LLC | 10,632 | 154,000 | 0.14% | ||
| 43 | INVESTMENT CENTERS OF AMERICA INC | 10,492 | 152,000 | 0.14% | ||
| 44 | VSR Financial Services, Inc. | 10,371 | 150,000 | 0.14% | ||
| 45 | Weiss Multi-Strategy Advisers LLC | 10,000 | 145,000 | 0.14% | ||
| 46 | SG Americas Securities, LLC | 9,647 | 140,000 | 0.13% | ||
| 47 | Creative Planning | 8,794 | 128,000 | 0.12% | ||
| 48 | DekaBank Deutsche Girozentrale | 6,600 | 99,000 | 0.09% | ||
| 49 | WELLS FARGO & COMPANY/MN | 4,944 | 72,000 | 0.07% | ||
| 50 | CITIGROUP INC | 1,826 | 26,000 | 0.02% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
