| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | FMR LLC | 14,477,611 | 152,594,000 | 16.15% | ||
| 2 | OppenheimerFunds, Inc. | 9,176,578 | 96,721,000 | 10.24% | ||
| 3 | FRANKLIN RESOURCES INC | 9,078,447 | 95,688,000 | 10.13% | ||
| 4 | VANGUARD GROUP INC | 6,572,533 | 69,275,000 | 7.33% | ||
| 5 | FIRST TRUST ADVISORS LP | 4,809,887 | 50,696,000 | 5.37% | ||
| 6 | BlackRock Fund Advisors | 3,761,916 | 39,651,000 | 4.20% | ||
| 7 | FRONTIER CAPITAL MANAGEMENT CO LLC | 3,498,712 | 36,876,000 | 3.90% | ||
| 8 | STATE STREET CORP | 3,191,036 | 33,635,000 | 3.56% | ||
| 9 | COLUMBIA WANGER ASSET MANAGEMENT LLC | 3,109,615 | 32,775,000 | 3.47% | ||
| 10 | BlackRock Institutional Trust Company, N.A. | 2,303,450 | 24,278,000 | 2.57% | ||
| 11 | Redmile Group, LLC | 1,954,019 | 20,595,000 | 2.18% | ||
| 12 | ALPS ADVISORS INC | 154,146 | 16,247,000 | 1.72% | ||
| 13 | DEUTSCHE BANK AG\ | 1,421,786 | 14,983,000 | 1.59% | ||
| 14 | UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 1,223,015 | 12,891,000 | 1.36% | ||
| 15 | NORTHERN TRUST CORP | 1,086,042 | 11,446,000 | 1.21% | ||
| 16 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 891,358 | 9,395,000 | 0.99% | ||
| 17 | TSP Capital Management Group, LLC | 824,681 | 8,692,000 | 0.92% | ||
| 18 | MORGAN STANLEY | 802,538 | 8,457,000 | 0.90% | ||
| 19 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 793,900 | 8,368,000 | 0.89% | Put | |
| 20 | MILLENNIUM MANAGEMENT LLC | 764,343 | 8,056,000 | 0.85% | ||
| 21 | RTW INVESTMENTS, LP | 718,729 | 7,575,000 | 0.80% | ||
| 22 | NORGES BANK | 667,128 | 7,032,000 | 0.74% | ||
| 23 | VOYA INVESTMENT MANAGEMENT LLC | 664,386 | 7,003,000 | 0.74% | ||
| 24 | GEODE CAPITAL MANAGEMENT, LLC | 636,205 | 6,705,000 | 0.71% | ||
| 25 | GROUP ONE TRADING LLC | 627,278 | 6,612,000 | 0.70% | ||
| 26 | Capital World Investors | 627,000 | 6,609,000 | 0.70% | ||
| 27 | WELLS FARGO & COMPANY/MN | 617,867 | 6,513,000 | 0.69% | ||
| 28 | Invesco Ltd. | 611,730 | 6,447,000 | 0.68% | ||
| 29 | COLUMBUS CIRCLE INVESTORS | 593,493 | 6,255,000 | 0.66% | ||
| 30 | First Eagle Investment Management, LLC | 559,542 | 5,898,000 | 0.62% | ||
| 31 | State of New Jersey Common Pension Fund D | 475,000 | 5,007,000 | 0.53% | ||
| 32 | Bank of New York Mellon Corp | 464,228 | 4,892,000 | 0.52% | ||
| 33 | GUGGENHEIM CAPITAL LLC | 414,412 | 4,368,000 | 0.46% | ||
| 34 | TIAA CREF INVESTMENT MANAGEMENT LLC | 379,090 | 3,996,000 | 0.42% | ||
| 35 | FRED ALGER MANAGEMENT, LLC | 376,207 | 3,965,000 | 0.42% | ||
| 36 | Artal Group S.A. | 375,000 | 3,953,000 | 0.42% | ||
| 37 | TEACHERS ADVISORS, LLC | 349,140 | 3,680,000 | 0.39% | ||
| 38 | Tekla Capital Management LLC | 338,400 | 3,567,000 | 0.38% | ||
| 39 | BlackRock Investment Management, LLC | 331,682 | 3,496,000 | 0.37% | ||
| 40 | LORD, ABBETT & CO. LLC | 323,274 | 3,407,000 | 0.36% | ||
| 41 | JPMORGAN CHASE & CO | 315,099 | 3,321,000 | 0.35% | ||
| 42 | CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 310,938 | 3,278,000 | 0.35% | ||
| 43 | Rhenman & Partners Asset Management AB | 295,000 | 3,109,000 | 0.33% | ||
| 44 | GOLDMAN SACHS GROUP INC | 254,146 | 2,679,000 | 0.28% | ||
| 45 | Zurcher Kantonalbank (Zurich Cantonalbank) | 243,784 | 2,569,000 | 0.27% | ||
| 46 | EVENTIDE ASSET MANAGEMENT, LLC | 228,800 | 2,412,000 | 0.26% | ||
| 47 | CALIFORNIA PUBLIC EMPLOYEES RETIREMENT SYSTEM | 219,900 | 2,318,000 | 0.25% | ||
| 48 | AMERIPRISE FINANCIAL INC | 219,710 | 2,316,000 | 0.25% | ||
| 49 | First Light Asset Management, LLC | 215,137 | 2,268,000 | 0.24% | ||
| 50 | NEW YORK STATE COMMON RETIREMENT FUND | 215,004 | 2,266,000 | 0.24% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
