| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | ALNYLAM PHARMACEUTICALS INC | 533,660 | 42,885,000 | 13.32% | ||
| 2 | INCYTE | 303,212 | 33,453,000 | 10.39% | ||
| 3 | LA JOLLA PHARMACEUTICAL CO | 1,080,331 | 30,022,000 | 9.33% | ||
| 4 | BIOCRYST PHARMACEUTICALS | 2,228,206 | 25,402,000 | 7.89% | ||
| 5 | KITE PHARMA INCORPORATED | 375,476 | 20,907,000 | 6.50% | ||
| 6 | ACHILLION PHARMACEUTICALS INC COM | 2,589,818 | 17,896,000 | 5.56% | ||
| 7 | MIRATI THERAPEUTICS INC COM | 482,069 | 16,593,000 | 5.16% | ||
| 8 | Dicerna Pharmaceuticals | 2,005,238 | 16,463,000 | 5.12% | ||
| 9 | BLUEBIRD BIO INCORPORATED | 151,594 | 12,969,000 | 4.03% | ||
| 10 | ARROWHEAD RESH CORP COM NEW | 2,097,185 | 12,080,000 | 3.75% | ||
| 11 | FIVE PRIME THERAPEUTICS INC | 713,954 | 10,988,000 | 3.41% | ||
| 12 | AGENUS INC | 2,084,142 | 9,587,000 | 2.98% | ||
| 13 | Atara Biotherapeutics Inc. | 262,995 | 8,269,000 | 2.57% | ||
| 14 | CELLDEX THERAPEUTICS INC NEW | 718,729 | 7,575,000 | 2.35% | ||
| 15 | SYMMETRY SURGICAL INC | 807,442 | 7,186,000 | 2.23% | ||
| 16 | BRISTOL MYERS SQUIBB CO | 102,425 | 6,064,000 | 1.88% | ||
| 17 | CORIUM INTERNATIONAL INC | 575,212 | 5,378,000 | 1.67% | ||
| 18 | OMEROS CORP | 490,000 | 5,370,000 | 1.67% | ||
| 19 | REGENXBIO INC COM | 204,494 | 4,505,000 | 1.40% | ||
| 20 | GLOBAL BLOOD THERAPEUTICS IN COM | 92,399 | 3,896,000 | 1.21% | ||
| 21 | BRISTOL MYERS SQUIBB CO | 7,500 | 2,588,000 | 0.80% | Call | |
| 22 | LIPOCINE INC NEW | 212,497 | 2,514,000 | 0.78% | ||
| 23 | INVUITY INC | 175,000 | 2,454,000 | 0.76% | ||
| 24 | DYAX CORP COM CVR | 115,358 | 2,202,000 | 0.68% | ||
| 25 | Presbia, PLC (Ireland) | 350,000 | 1,918,000 | 0.60% | ||
| 26 | Catalyst Biosciences | 380,806 | 1,775,000 | 0.55% | ||
| 27 | REPROS THERAPEUTICS INC | 232,830 | 1,730,000 | 0.54% | ||
| 28 | VBI Vaccines Inc. | 650,000 | 1,716,000 | 0.53% | ||
| 29 | ORASURE TECHNOLOGIES INC | 322,996 | 1,434,000 | 0.45% | ||
| 30 | CYTRX CORP | 453,465 | 1,075,000 | 0.33% | ||
| 31 | NEWLINK GENETICS CORP | 28,291 | 1,014,000 | 0.32% | ||
| 32 | MASIMO CORP COM | 25,900 | 999,000 | 0.31% | ||
| 33 | ALLSCRIPTS HEALTHCARE | 48,000 | 595,000 | 0.18% | ||
| 34 | BIOCRYST PHARMACEUTICALS | 2,000 | 431,000 | 0.13% | Call | |
| 35 | Nivalis Therapeutics Inc | 30,000 | 389,000 | 0.12% | ||
| 36 | BIOPHARMX CORP COM | 370,636 | 382,000 | 0.12% | ||
| 37 | NATERA INC | 31,693 | 344,000 | 0.11% | ||
| 38 | GENOMIC HEALTH INC COM | 15,000 | 317,000 | 0.10% | ||
| 39 | ENDOLOGIX INC | 15,000 | 184,000 | 0.06% | ||
| 40 | VERACYTE INC | 25,000 | 117,000 | 0.04% | ||
| 41 | ADAPTIMMUNE THERAPEUTICS PLC | 7,028 | 84,000 | 0.03% | ||
| 42 | MERIDIAN BIOSCIENCE INC COM | 1,252 | 50,000 | 0.02% | Call | |
| 43 | UNITED STATES | 13,850 | 42,000 | 0.01% | Call | |
| 44 | BERKSHIRE HATHAWAY INC DE CL B NEW | 50 | 7,000 | 0.00% |
Portfolio data is normalized using SEC Form 13F filings, including the Restatement filing (0001493152-16-010243, filed 2016.05.24).
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
