| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | Third Security, LLC | 17,815,708 | 71,797,000 | 35.40% | ||
| 2 | FMR LLC | 4,413,607 | 17,787,000 | 8.77% | ||
| 3 | STATE STREET CORP | 3,753,085 | 15,125,000 | 7.46% | ||
| 4 | VANGUARD GROUP INC | 2,855,937 | 11,509,000 | 5.67% | ||
| 5 | MSD Partners, L.P. | 2,750,000 | 11,083,000 | 5.46% | ||
| 6 | Essex Woodlands Management, Inc. | 2,764,908 | 10,257,000 | 5.06% | ||
| 7 | BlackRock Fund Advisors | 2,032,142 | 8,190,000 | 4.04% | ||
| 8 | JENNISON ASSOCIATES LLC | 1,515,784 | 6,109,000 | 3.01% | ||
| 9 | MORGAN STANLEY | 1,188,377 | 4,790,000 | 2.36% | ||
| 10 | BlackRock Institutional Trust Company, N.A. | 1,050,798 | 4,235,000 | 2.09% | ||
| 11 | NORTHERN TRUST CORP | 948,188 | 3,821,000 | 1.88% | ||
| 12 | GROUP ONE TRADING LLC | 617,836 | 2,490,000 | 1.23% | ||
| 13 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 599,400 | 2,416,000 | 1.19% | Call | |
| 14 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 589,200 | 2,374,000 | 1.17% | Put | |
| 15 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 552,151 | 2,225,000 | 1.10% | ||
| 16 | GEODE CAPITAL MANAGEMENT, LLC | 535,039 | 2,156,000 | 1.06% | ||
| 17 | Bank of New York Mellon Corp | 462,781 | 1,865,000 | 0.92% | ||
| 18 | CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 372,247 | 1,501,000 | 0.74% | ||
| 19 | Janney Montgomery Scott LLC | 352,973 | 1,422,481 | 0.70% | ||
| 20 | BARCLAYS PLC | 351,666 | 1,407,000 | 0.69% | ||
| 21 | TIAA CREF INVESTMENT MANAGEMENT LLC | 333,863 | 1,345,000 | 0.66% | ||
| 22 | UBS AG | 328,314 | 1,323,000 | 0.65% | ||
| 23 | COMMERCE BANK | 300,000 | 1,209,000 | 0.60% | ||
| 24 | ROYCE & ASSOCIATES LP | 268,000 | 1,080,000 | 0.53% | ||
| 25 | BAKER BROS. ADVISORS LP | 244,619 | 986,000 | 0.49% | ||
| 26 | SMITH ASSET MANAGEMENT GROUP LP | 237,410 | 957,000 | 0.47% | ||
| 27 | BlackRock Investment Management, LLC | 237,016 | 955,000 | 0.47% | ||
| 28 | CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 148,191 | 597,000 | 0.29% | ||
| 29 | AQR CAPITAL MANAGEMENT LLC | 124,900 | 503,000 | 0.25% | ||
| 30 | DEUTSCHE BANK AG\ | 115,415 | 464,000 | 0.23% | ||
| 31 | TEACHERS ADVISORS, LLC | 115,001 | 463,000 | 0.23% | ||
| 32 | A.R.T. Advisors, LLC | 112,519 | 453,000 | 0.22% | ||
| 33 | Belmont Global Advisors, Inc. | 110,700 | 446,000 | 0.22% | Call | |
| 34 | PNC FINANCIAL SERVICES GROUP, INC. | 106,930 | 431,000 | 0.21% | ||
| 35 | SFMG, LLC | 99,850 | 402,000 | 0.20% | ||
| 36 | ALLIANCEBERNSTEIN L.P. | 97,000 | 391,000 | 0.19% | ||
| 37 | Swiss National Bank | 95,600 | 385,000 | 0.19% | ||
| 38 | CREDIT SUISSE AG/ | 88,567 | 358,000 | 0.18% | ||
| 39 | BANK OF AMERICA CORP /DE/ | 87,702 | 353,000 | 0.17% | ||
| 40 | PARAMETRIC PORTFOLIO ASSOCIATES LLC | 87,220 | 352,000 | 0.17% | ||
| 41 | Spot Trading L.L.C | 85,000 | 343,000 | 0.17% | Call | |
| 42 | D. E. Shaw & Co., Inc. | 82,221 | 331,000 | 0.16% | ||
| 43 | AMERICAN INTERNATIONAL GROUP, INC. | 73,103 | 294,605 | 0.15% | ||
| 44 | FRANKLIN STREET ADVISORS INC /NC | 68,700 | 277,000 | 0.14% | ||
| 45 | RHUMBLINE ADVISERS | 64,714 | 261,000 | 0.13% | ||
| 46 | Nationwide Fund Advisors | 63,579 | 256,000 | 0.13% | ||
| 47 | CITADEL ADVISORS LLC | 61,460 | 248,000 | 0.12% | ||
| 48 | METROPOLITAN LIFE INSURANCE CO/NY | 60,334 | 243,000 | 0.12% | ||
| 49 | BLACKROCK ADVISORS LLC | 55,561 | 224,000 | 0.11% | ||
| 50 | STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM | 54,566 | 220,000 | 0.11% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
