| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | Third Security, LLC | 17,815,708 | 81,596,000 | 32.66% | ||
| 2 | FMR LLC | 7,458,071 | 34,158,000 | 13.67% | ||
| 3 | STATE STREET CORP | 4,207,715 | 19,273,000 | 7.71% | ||
| 4 | MSD Partners, L.P. | 2,750,000 | 12,595,000 | 5.04% | ||
| 5 | Essex Woodlands Management, Inc. | 2,764,908 | 11,799,000 | 4.72% | ||
| 6 | VANGUARD GROUP INC | 2,538,893 | 11,628,000 | 4.65% | ||
| 7 | BlackRock Fund Advisors | 2,251,715 | 10,313,000 | 4.13% | ||
| 8 | JENNISON ASSOCIATES LLC | 1,687,709 | 7,730,000 | 3.09% | ||
| 9 | BlackRock Institutional Trust Company, N.A. | 1,166,732 | 5,344,000 | 2.14% | ||
| 10 | MORGAN STANLEY | 1,159,493 | 5,310,000 | 2.13% | ||
| 11 | NORTHERN TRUST CORP | 1,079,369 | 4,944,000 | 1.98% | ||
| 12 | BARCLAYS PLC | 1,036,887 | 4,149,000 | 1.66% | ||
| 13 | Invesco Ltd. | 722,342 | 3,308,000 | 1.32% | ||
| 14 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 541,900 | 2,482,000 | 0.99% | Call | |
| 15 | GEODE CAPITAL MANAGEMENT, LLC | 532,796 | 2,440,000 | 0.98% | ||
| 16 | Bank of New York Mellon Corp | 461,314 | 2,113,000 | 0.85% | ||
| 17 | GROUP ONE TRADING LLC | 394,863 | 1,808,000 | 0.72% | ||
| 18 | Janney Montgomery Scott LLC | 340,776 | 1,560,754 | 0.62% | ||
| 19 | ROYCE & ASSOCIATES LP | 331,000 | 1,516,000 | 0.61% | ||
| 20 | TIAA CREF INVESTMENT MANAGEMENT LLC | 320,933 | 1,470,000 | 0.59% | ||
| 21 | COMMERCE BANK | 300,000 | 1,374,000 | 0.55% | ||
| 22 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 295,300 | 1,352,000 | 0.54% | Put | |
| 23 | UBS AG | 279,046 | 1,278,000 | 0.51% | ||
| 24 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 277,589 | 1,272,000 | 0.51% | ||
| 25 | CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 261,607 | 1,199,000 | 0.48% | ||
| 26 | BAKER BROS. ADVISORS LP | 244,619 | 1,120,000 | 0.45% | ||
| 27 | BlackRock Investment Management, LLC | 223,221 | 1,022,000 | 0.41% | ||
| 28 | PARAMETRIC PORTFOLIO ASSOCIATES LLC | 177,521 | 813,000 | 0.33% | ||
| 29 | SMITH ASSET MANAGEMENT GROUP LP | 152,660 | 699,000 | 0.28% | ||
| 30 | CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 145,591 | 667,000 | 0.27% | ||
| 31 | CREDIT SUISSE AG/ | 121,287 | 555,000 | 0.22% | ||
| 32 | TEACHERS ADVISORS, LLC | 119,351 | 547,000 | 0.22% | ||
| 33 | SABBY MANAGEMENT, LLC | 110,573 | 506,000 | 0.20% | ||
| 34 | PNC FINANCIAL SERVICES GROUP, INC. | 106,930 | 491,000 | 0.20% | ||
| 35 | DEUTSCHE BANK AG\ | 105,173 | 481,000 | 0.19% | ||
| 36 | OXFORD ASSET MANAGEMENT LLP | 103,001 | 472,000 | 0.19% | ||
| 37 | SFMG, LLC | 99,850 | 457,000 | 0.18% | ||
| 38 | Swiss National Bank | 95,600 | 438,000 | 0.18% | ||
| 39 | A.R.T. Advisors, LLC | 91,657 | 419,000 | 0.17% | ||
| 40 | JACOBS LEVY EQUITY MANAGEMENT, INC | 88,100 | 403,000 | 0.16% | ||
| 41 | ALLIANCEBERNSTEIN L.P. | 88,017 | 403,000 | 0.16% | ||
| 42 | Spot Trading L.L.C | 85,000 | 389,000 | 0.16% | Call | |
| 43 | RENAISSANCE TECHNOLOGIES LLC | 83,774 | 384,000 | 0.15% | ||
| 44 | ProShare Advisors LLC | 81,441 | 373,000 | 0.15% | ||
| 45 | AMERICAN INTERNATIONAL GROUP, INC. | 74,696 | 342,108 | 0.14% | ||
| 46 | FRANKLIN STREET ADVISORS INC /NC | 64,100 | 294,000 | 0.12% | ||
| 47 | MANUFACTURERS LIFE INSURANCE COMPANY, THE | 62,825 | 288,000 | 0.12% | ||
| 48 | BLACKROCK ADVISORS LLC | 62,096 | 284,000 | 0.11% | ||
| 49 | Nationwide Fund Advisors | 61,813 | 283,000 | 0.11% | ||
| 50 | RHUMBLINE ADVISERS | 60,639 | 278,000 | 0.11% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
