| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | Third Security, LLC | 17,815,708 | 47,033,000 | 36.69% | ||
| 2 | STATE STREET CORP | 3,244,772 | 8,564,000 | 6.68% | ||
| 3 | FMR LLC | 3,134,700 | 8,276,000 | 6.46% | ||
| 4 | MSD Partners, L.P. | 2,750,000 | 7,260,000 | 5.66% | ||
| 5 | Essex Woodlands Management, Inc. | 2,764,908 | 7,130,000 | 5.56% | ||
| 6 | VANGUARD GROUP INC | 2,688,407 | 7,098,000 | 5.54% | ||
| 7 | BlackRock Fund Advisors | 1,967,326 | 5,194,000 | 4.05% | ||
| 8 | JENNISON ASSOCIATES LLC | 1,517,997 | 4,008,000 | 3.13% | ||
| 9 | MORGAN STANLEY | 1,272,737 | 3,359,000 | 2.62% | ||
| 10 | BlackRock Institutional Trust Company, N.A. | 981,120 | 2,590,000 | 2.02% | ||
| 11 | NORTHERN TRUST CORP | 928,099 | 2,450,000 | 1.91% | ||
| 12 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 626,400 | 1,654,000 | 1.29% | Call | |
| 13 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 620,200 | 1,637,000 | 1.28% | Put | |
| 14 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 593,351 | 1,566,000 | 1.22% | ||
| 15 | Bank of New York Mellon Corp | 539,805 | 1,425,000 | 1.11% | ||
| 16 | GEODE CAPITAL MANAGEMENT, LLC | 539,449 | 1,424,000 | 1.11% | ||
| 17 | GROUP ONE TRADING LLC | 434,874 | 1,148,000 | 0.90% | ||
| 18 | CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 429,737 | 1,135,000 | 0.89% | ||
| 19 | Janney Montgomery Scott LLC | 331,923 | 876,277 | 0.68% | ||
| 20 | TIAA CREF INVESTMENT MANAGEMENT LLC | 322,651 | 852,000 | 0.66% | ||
| 21 | COMMERCE BANK | 300,000 | 792,000 | 0.62% | ||
| 22 | RENAISSANCE TECHNOLOGIES LLC | 268,341 | 708,000 | 0.55% | ||
| 23 | ROYCE & ASSOCIATES LP | 268,000 | 708,000 | 0.55% | ||
| 24 | UBS AG | 252,833 | 667,000 | 0.52% | ||
| 25 | BAKER BROS. ADVISORS LP | 244,619 | 646,000 | 0.50% | ||
| 26 | BlackRock Investment Management, LLC | 238,224 | 629,000 | 0.49% | ||
| 27 | SMITH ASSET MANAGEMENT GROUP LP | 236,590 | 625,000 | 0.49% | ||
| 28 | NOMURA HOLDINGS INC | 148,908 | 394,000 | 0.31% | ||
| 29 | CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 149,142 | 394,000 | 0.31% | ||
| 30 | BARCLAYS PLC | 183,375 | 366,000 | 0.29% | ||
| 31 | Belmont Global Advisors, Inc. | 135,700 | 358,000 | 0.28% | Call | |
| 32 | AQR CAPITAL MANAGEMENT LLC | 127,000 | 335,000 | 0.26% | ||
| 33 | GOLDMAN SACHS GROUP INC | 122,049 | 322,000 | 0.25% | ||
| 34 | PNC FINANCIAL SERVICES GROUP, INC. | 115,886 | 307,000 | 0.24% | ||
| 35 | A.R.T. Advisors, LLC | 115,919 | 306,000 | 0.24% | ||
| 36 | TEACHERS ADVISORS, LLC | 115,001 | 304,000 | 0.24% | ||
| 37 | DEUTSCHE BANK AG\ | 103,347 | 272,000 | 0.21% | ||
| 38 | SFMG, LLC | 99,850 | 264,000 | 0.21% | ||
| 39 | ALLIANCEBERNSTEIN L.P. | 97,000 | 256,000 | 0.20% | ||
| 40 | Swiss National Bank | 95,600 | 252,000 | 0.20% | ||
| 41 | CITADEL ADVISORS LLC | 91,715 | 242,000 | 0.19% | ||
| 42 | Spot Trading L.L.C | 85,000 | 224,000 | 0.17% | Call | |
| 43 | PARAMETRIC PORTFOLIO ASSOCIATES LLC | 83,053 | 219,000 | 0.17% | ||
| 44 | AMERICAN INTERNATIONAL GROUP, INC. | 73,063 | 192,886 | 0.15% | ||
| 45 | CREDIT SUISSE AG/ | 72,781 | 191,000 | 0.15% | ||
| 46 | RHUMBLINE ADVISERS | 64,714 | 171,000 | 0.13% | ||
| 47 | PRICE T ROWE ASSOCIATES INC /MD/ | 63,200 | 167,000 | 0.13% | ||
| 48 | Nationwide Fund Advisors | 62,394 | 165,000 | 0.13% | ||
| 49 | METROPOLITAN LIFE INSURANCE CO/NY | 60,334 | 159,000 | 0.12% | ||
| 50 | AMERICAN CENTURY COMPANIES INC | 56,899 | 150,000 | 0.12% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
