| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | FMR LLC | 3,804,279 | 102,487,000 | 36.98% | ||
| 2 | RA CAPITAL MANAGEMENT, L.P. | 2,564,553 | 69,089,000 | 24.93% | ||
| 3 | FRANKLIN RESOURCES INC | 1,654,894 | 44,583,000 | 16.08% | ||
| 4 | Rock Springs Capital Management LP | 896,154 | 24,142,000 | 8.71% | ||
| 5 | Cormorant Asset Management, LP | 647,944 | 17,456,000 | 6.30% | ||
| 6 | BlackRock Fund Advisors | 155,186 | 4,181,000 | 1.51% | ||
| 7 | VANGUARD GROUP INC | 149,988 | 4,040,000 | 1.46% | ||
| 8 | TURNER INVESTMENTS LLC | 57,694 | 1,554,000 | 0.56% | ||
| 9 | NORTHERN TRUST CORP | 57,142 | 1,539,000 | 0.56% | ||
| 10 | NORGES BANK | 50,000 | 1,347,000 | 0.49% | ||
| 11 | STATE STREET CORP | 44,653 | 1,202,000 | 0.43% | ||
| 12 | Spark Investment Management LLC | 38,616 | 1,040,000 | 0.38% | ||
| 13 | GEODE CAPITAL MANAGEMENT, LLC | 36,567 | 985,000 | 0.36% | ||
| 14 | BlackRock Institutional Trust Company, N.A. | 22,751 | 613,000 | 0.22% | ||
| 15 | BlackRock Investment Management, LLC | 19,973 | 538,000 | 0.19% | ||
| 16 | CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 16,557 | 447,000 | 0.16% | ||
| 17 | Bank of New York Mellon Corp | 14,283 | 385,000 | 0.14% | ||
| 18 | Geduld E E | 13,000 | 350,000 | 0.13% | ||
| 19 | TIAA CREF INVESTMENT MANAGEMENT LLC | 12,953 | 349,000 | 0.13% | ||
| 20 | CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 10,650 | 287,000 | 0.10% | ||
| 21 | TEACHERS ADVISORS, LLC | 5,687 | 153,000 | 0.06% | ||
| 22 | Nationwide Fund Advisors | 3,418 | 92,000 | 0.03% | ||
| 23 | BLACKROCK ADVISORS LLC | 1,937 | 52,000 | 0.02% | ||
| 24 | STRS OHIO | 1,900 | 51,000 | 0.02% | ||
| 25 | CITIGROUP INC | 1,736 | 47,000 | 0.02% | ||
| 26 | WELLS FARGO & COMPANY/MN | 1,660 | 45,000 | 0.02% | ||
| 27 | DEUTSCHE BANK AG\ | 1,446 | 38,000 | 0.01% | ||
| 28 | BARCLAYS PLC | 1,000 | 26,000 | 0.01% | ||
| 29 | Tower Research Capital LLC (TRC) | 812 | 22,000 | 0.01% | ||
| 30 | BNP PARIBAS FINANCIAL MARKETS | 519 | 13,982 | 0.01% | ||
| 31 | MORGAN STANLEY | 391 | 11,000 | 0.00% | ||
| 32 | BANK OF AMERICA CORP /DE/ | 139 | 4,000 | 0.00% | ||
| 33 | UBS Group AG | 109 | 3,000 | 0.00% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
