| 1 |
FMR LLC |
3,902,348 |
34,067,000 |
39.17% |
|
|
| 2 |
Bain Capital Public Equity Management, LLC |
1,523,010 |
13,296,000 |
15.29% |
|
|
| 3 |
WELLINGTON MANAGEMENT GROUP LLP |
954,140 |
8,330,000 |
9.58% |
|
|
| 4 |
PFM Health Sciences, LP |
893,541 |
7,345,000 |
8.45% |
|
|
| 5 |
GOLDMAN SACHS GROUP INC |
797,817 |
6,965,000 |
8.01% |
|
|
| 6 |
CASDIN CAPITAL, LLC |
339,362 |
2,963,000 |
3.41% |
|
|
| 7 |
JANUS HENDERSON INVESTORS US LLC |
305,101 |
2,664,000 |
3.06% |
|
|
| 8 |
EVENTIDE ASSET MANAGEMENT, LLC |
300,000 |
2,619,000 |
3.01% |
|
|
| 9 |
DEERFIELD MANAGEMENT COMPANY, L.P. |
235,294 |
2,054,000 |
2.36% |
|
|
| 10 |
BlackRock Fund Advisors |
146,528 |
1,279,000 |
1.47% |
|
|
| 11 |
JPMORGAN CHASE & CO |
106,300 |
928,000 |
1.07% |
|
|
| 12 |
ADAGE CAPITAL PARTNERS GP, L.L.C. |
100,000 |
873,000 |
1.00% |
|
|
| 13 |
STATE STREET CORP |
57,705 |
502,000 |
0.58% |
|
|
| 14 |
NORTHERN TRUST CORP |
54,990 |
480,000 |
0.55% |
|
|
| 15 |
GEODE CAPITAL MANAGEMENT, LLC |
52,472 |
458,000 |
0.53% |
|
|
| 16 |
GLOBEFLEX CAPITAL L P |
40,200 |
351,000 |
0.40% |
|
|
| 17 |
BlackRock Institutional Trust Company, N.A. |
31,316 |
273,000 |
0.31% |
|
|
| 18 |
Bank of New York Mellon Corp |
23,472 |
205,000 |
0.24% |
|
|
| 19 |
BlackRock Investment Management, LLC |
20,324 |
177,000 |
0.20% |
|
|
| 20 |
VANGUARD GROUP INC |
19,693 |
172,000 |
0.20% |
|
|
| 21 |
UNITED SERVICES AUTOMOBILE ASSOCIATION |
19,200 |
168,000 |
0.19% |
|
|
| 22 |
CHARLES SCHWAB INVESTMENT MANAGEMENT INC |
17,271 |
151,000 |
0.17% |
|
|
| 23 |
Partner Investment Management, L.P. |
14,335 |
120,000 |
0.14% |
|
|
| 24 |
CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM |
12,488 |
109,000 |
0.13% |
|
|
| 25 |
TIAA CREF INVESTMENT MANAGEMENT LLC |
12,039 |
105,000 |
0.12% |
|
|
| 26 |
TEACHERS ADVISORS, LLC |
5,862 |
51,000 |
0.06% |
|
|
| 27 |
CITIGROUP INC |
4,684 |
41,000 |
0.05% |
|
|
| 28 |
Tower Research Capital LLC (TRC) |
3,450 |
30,000 |
0.03% |
|
|
| 29 |
AMERICAN INTERNATIONAL GROUP, INC. |
3,362 |
29,000 |
0.03% |
|
|
| 30 |
Nationwide Fund Advisors |
3,373 |
29,000 |
0.03% |
|
|
| 31 |
MANUFACTURERS LIFE INSURANCE COMPANY, THE |
2,867 |
25,000 |
0.03% |
|
|
| 32 |
NEW YORK STATE COMMON RETIREMENT FUND |
2,900 |
25,000 |
0.03% |
|
|
| 33 |
BLACKROCK ADVISORS LLC |
1,959 |
17,000 |
0.02% |
|
|
| 34 |
STRS OHIO |
1,900 |
16,000 |
0.02% |
|
|
| 35 |
WELLS FARGO & COMPANY/MN |
1,656 |
14,000 |
0.02% |
|
|
| 36 |
UBS Group AG |
1,390 |
12,000 |
0.01% |
|
|
| 37 |
ACADIAN ASSET MANAGEMENT LLC |
1,209 |
11,000 |
0.01% |
|
|
| 38 |
MORGAN STANLEY |
832 |
7,000 |
0.01% |
|
|
| 39 |
DEUTSCHE BANK AG\ |
871 |
7,000 |
0.01% |
|
|
| 40 |
BANK OF AMERICA CORP /DE/ |
460 |
4,000 |
0.00% |
|
|
| 41 |
BlackRock Finance, Inc. |
88 |
1,000 |
0.00% |
|
|
| 42 |
BNP PARIBAS FINANCIAL MARKETS |
94 |
821 |
0.00% |
|
|
