| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | ADAGE CAPITAL PARTNERS GP, L.L.C. | 1,229,830 | 38,457,000 | 21.39% | ||
| 2 | PRICE T ROWE ASSOCIATES INC /MD/ | 1,960,960 | 37,347,000 | 20.77% | ||
| 3 | SCOPIA CAPITAL MANAGEMENT LP | 897,687 | 28,071,000 | 15.61% | ||
| 4 | Rock Springs Capital Management LP | 800,000 | 25,016,000 | 13.91% | ||
| 5 | BAKER BROS. ADVISORS LP | 567,454 | 17,744,000 | 9.87% | ||
| 6 | JANUS HENDERSON INVESTORS US LLC | 331,974 | 10,381,000 | 5.77% | ||
| 7 | FEDERATED HERMES, INC. | 304,809 | 9,531,000 | 5.30% | ||
| 8 | Sio Capital Management, LLC | 291,877 | 9,127,000 | 5.08% | ||
| 9 | MILLENNIUM MANAGEMENT LLC | 51,114 | 1,598,000 | 0.89% | ||
| 10 | ALPS ADVISORS INC | 50,816 | 1,589,000 | 0.88% | ||
| 11 | TD ASSET MANAGEMENT INC | 13,250 | 414,000 | 0.23% | ||
| 12 | LANDSCAPE CAPITAL MANAGEMENT, L.L.C. | 8,052 | 252,000 | 0.14% | ||
| 13 | NEXTHERA CAPITAL LP | 7,500 | 235,000 | 0.13% | ||
| 14 | ACADIAN ASSET MANAGEMENT LLC | 1,151 | 36,000 | 0.02% | ||
| 15 | Tower Research Capital LLC (TRC) | 16 | 1,000 | 0.00% | ||
| 16 | First Horizon Advisors, Inc. | 3 | 0 | 0.00% | ||
| 17 | CITIGROUP INC | 15 | 0 | 0.00% | ||
| 18 | LADENBURG THALMANN FINANCIAL SERVICES INC. | 10 | 0 | 0.00% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
