| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | INCYTE CORP | 19,475,316 | 2,112,098,000 | 17.50% | ||
| 2 | SEATTLE GENETICS INC | 37,293,728 | 1,673,743,000 | 13.87% | ||
| 3 | ALEXION PHARMACEUTICALS | 6,542,599 | 1,248,001,000 | 10.34% | ||
| 4 | ABBVIE INC | 14,373,538 | 851,488,000 | 7.05% | ||
| 5 | ACADIA PHARMACEUTICALS INC | 20,481,442 | 730,163,000 | 6.05% | ||
| 6 | Incyte Corporation | 274,500,000 | 596,530,000 | 4.94% | PRN | |
| 7 | Incyte Corporation | 259,000,000 | 556,688,000 | 4.61% | PRN | |
| 8 | GENOMIC HEALTH INC | 13,659,264 | 480,806,000 | 3.98% | ||
| 9 | Anacor Pharmaceuticals Inc | 4,198,520 | 474,307,000 | 3.93% | ||
| 10 | BIOMARIN PHARMACEUTICAL INC | 4,115,083 | 431,096,000 | 3.57% | ||
| 11 | DYAX CORP COM CVR | 8,310,017 | 312,623,000 | 2.59% | ||
| 12 | DBV TECHNOLOGIES S A | 5,462,019 | 198,326,000 | 1.64% | ||
| 13 | ACORDA THERAPEUTICS INC | 3,580,112 | 153,157,000 | 1.27% | ||
| 14 | ANACOR PHARMACEUTICALS INC | 42,000,000 | 152,294,000 | 1.26% | PRN | |
| 15 | BIOCRYST PHARMACEUTICALS | 14,217,779 | 146,727,000 | 1.22% | ||
| 16 | BioMarin Pharmaceutical Inc. | 22,379,000 | 115,158,000 | 0.95% | PRN | |
| 17 | CLOVIS ONCOLOGY INC | 129,300,000 | 110,982,000 | 0.92% | PRN | |
| 18 | BELLICUM PHARMACEUTICALS INC | 4,865,647 | 98,627,000 | 0.82% | ||
| 19 | GILEAD SCIENCES | 20,944,000 | 93,469,000 | 0.77% | PRN | |
| 20 | MIRATI THERAPEUTICS INC | 2,955,074 | 93,380,000 | 0.77% | ||
| 21 | Cerus Corp | 13,553,275 | 85,657,000 | 0.71% | ||
| 22 | AQUINOX PHARMACEUTICALS INC | 6,747,332 | 84,207,000 | 0.70% | ||
| 23 | HERON THERAPEUTICS INC | 2,907,784 | 77,638,000 | 0.64% | ||
| 24 | IMMUNOGEN INC | 4,452,445 | 60,420,000 | 0.50% | ||
| 25 | ACORDA THERAPEUTICS INC | 51,583,000 | 59,297,000 | 0.49% | PRN | |
| 26 | Spark Therapeutics, Inc. | 1,262,382 | 57,199,000 | 0.47% | ||
| 27 | INVITAE CORP | 6,554,967 | 53,816,000 | 0.45% | ||
| 28 | NEUROCRINE BIOSCIENCES INC | 850,739 | 48,126,000 | 0.40% | ||
| 29 | Versartis, Inc. | 3,241,783 | 40,166,000 | 0.33% | ||
| 30 | SANGAMO THERAPEUTICS INC | 4,055,876 | 37,030,000 | 0.31% | ||
| 31 | HALOZYME THERAPEUTICS INC | 1,931,057 | 33,465,000 | 0.28% | ||
| 32 | INTRA CELLULAR THERAPIES INC | 609,166 | 32,767,000 | 0.27% | ||
| 33 | MEDIVATION INC | 659,752 | 31,892,000 | 0.26% | ||
| 34 | PROGENICS PHARMACEUTICALS | 4,350,808 | 26,670,000 | 0.22% | ||
| 35 | GILEAD SCIENCES INC | 249,995 | 25,297,000 | 0.21% | ||
| 36 | TG THERAPEUTICS INC | 2,003,991 | 23,908,000 | 0.20% | ||
| 37 | Exelexis | 20,000,000 | 23,260,000 | 0.19% | PRN | |
| 38 | GALAPAGOS NV | 369,276 | 23,220,000 | 0.19% | ||
| 39 | ATYR PHARMA INC | 2,335,125 | 22,954,000 | 0.19% | ||
| 40 | ACHILLION PHARMACEUTICALS IN | 2,000,000 | 21,580,000 | 0.18% | ||
| 41 | IDERA PHARMACEUTICALS INC | 6,983,107 | 21,578,000 | 0.18% | ||
| 42 | Catalyst Pharmaceuticals Inc | 8,275,630 | 20,275,000 | 0.17% | ||
| 43 | ALKERMES PLC | 250,251 | 19,865,000 | 0.16% | ||
| 44 | XENOPORT INC | 3,475,672 | 19,081,000 | 0.16% | ||
| 45 | NOVAVAX INC | 2,195,687 | 18,422,000 | 0.15% | ||
| 46 | Array BioPharma Inc. | 4,310,666 | 18,191,000 | 0.15% | ||
| 47 | INSMED INC | 1,000,000 | 18,150,000 | 0.15% | ||
| 48 | ADVANCED ACCELERATOR APPLIC | 567,454 | 17,744,000 | 0.15% | ||
| 49 | AEGERION PHARMACEUTICALS INC | 26,517,000 | 17,552,000 | 0.15% | PRN | |
| 50 | DERMA SCIENCES INC COM PAR .01 | 3,752,390 | 17,148,000 | 0.14% |
Portfolio data is normalized using SEC Form 13F filings, including the Original 13F-HR (0001144204-16-082790, filed 2016.02.16).
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
