| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | FMR LLC | 5,901,489 | 131,721,000 | 21.11% | ||
| 2 | POLARIS VENTURE MANAGEMENT CO. VI, L.L.C. | 3,797,146 | 84,752,000 | 13.58% | ||
| 3 | FLAGSHIP VENTURES MANAGEMENT, INC. | 3,376,184 | 75,356,000 | 12.07% | ||
| 4 | VANGUARD GROUP INC | 1,935,173 | 43,193,000 | 6.92% | ||
| 5 | Capital World Investors | 1,770,000 | 39,506,000 | 6.33% | ||
| 6 | VIKING GLOBAL INVESTORS LP | 1,709,401 | 38,154,000 | 6.11% | ||
| 7 | DEERFIELD MANAGEMENT COMPANY, L.P. | 1,709,400 | 38,154,000 | 6.11% | ||
| 8 | PRICE T ROWE ASSOCIATES INC /MD/ | 1,401,696 | 31,286,000 | 5.01% | ||
| 9 | BlackRock Finance, Inc. | 1,118,488 | 24,966,000 | 4.00% | ||
| 10 | MILLENNIUM MANAGEMENT LLC | 564,699 | 12,604,000 | 2.02% | ||
| 11 | CLOUGH CAPITAL PARTNERS L P | 392,087 | 8,751,000 | 1.40% | ||
| 12 | MORGAN STANLEY | 308,909 | 6,895,000 | 1.10% | ||
| 13 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 283,900 | 6,337,000 | 1.02% | Put | |
| 14 | D. E. Shaw & Co., Inc. | 244,929 | 5,466,000 | 0.88% | ||
| 15 | ARK INVESTMENT MANAGEMENT LLC | 229,922 | 5,132,000 | 0.82% | ||
| 16 | HIGHLAND CAPITAL MANAGEMENT LP | 189,000 | 4,219,000 | 0.68% | ||
| 17 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 164,144 | 3,664,000 | 0.59% | ||
| 18 | CREDIT SUISSE AG/ | 154,013 | 3,437,000 | 0.55% | ||
| 19 | LMR Partners LLP | 153,190 | 3,419,000 | 0.55% | ||
| 20 | York Capital Management Global Advisors, LLC | 150,000 | 3,348,000 | 0.54% | ||
| 21 | CASDIN CAPITAL, LLC | 133,333 | 2,976,000 | 0.48% | ||
| 22 | STATE STREET CORP | 132,618 | 2,961,000 | 0.47% | ||
| 23 | DRIEHAUS CAPITAL MANAGEMENT LLC | 125,684 | 2,805,000 | 0.45% | ||
| 24 | GEODE CAPITAL MANAGEMENT, LLC | 119,376 | 2,664,000 | 0.43% | ||
| 25 | Shellback Capital, LP | 114,461 | 2,555,000 | 0.41% | ||
| 26 | NORTHERN TRUST CORP | 107,876 | 2,408,000 | 0.39% | ||
| 27 | Crestwood Advisors Group, LLC | 115,937 | 2,369,000 | 0.38% | ||
| 28 | Hudson Bay Capital Management LP | 100,000 | 2,232,000 | 0.36% | ||
| 29 | SABBY MANAGEMENT, LLC | 90,300 | 2,015,000 | 0.32% | ||
| 30 | CLARIUS GROUP, LLC | 87,231 | 1,947,000 | 0.31% | ||
| 31 | UBS Group AG | 78,217 | 1,746,000 | 0.28% | ||
| 32 | BARCLAYS PLC | 65,700 | 1,466,000 | 0.23% | Call | |
| 33 | WELLS FARGO & COMPANY/MN | 64,980 | 1,451,000 | 0.23% | ||
| 34 | Bank of New York Mellon Corp | 63,490 | 1,418,000 | 0.23% | ||
| 35 | THRIVENT FINANCIAL FOR LUTHERANS | 50,941 | 1,137,000 | 0.18% | ||
| 36 | GROUP ONE TRADING LLC | 50,222 | 1,121,000 | 0.18% | ||
| 37 | JANUS HENDERSON GROUP PLC | 50,000 | 1,116,000 | 0.18% | ||
| 38 | Omega Advisors Inc. | 50,000 | 1,116,000 | 0.18% | ||
| 39 | GRATICULE ASIA MACRO ADVISORS LLC | 50,000 | 1,116,000 | 0.18% | ||
| 40 | PAULSON & CO. INC. | 50,000 | 1,116,000 | 0.18% | ||
| 41 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 46,700 | 1,042,000 | 0.17% | Call | |
| 42 | VICTORY CAPITAL MANAGEMENT INC | 42,272 | 944,000 | 0.15% | ||
| 43 | CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 42,150 | 941,000 | 0.15% | ||
| 44 | Wildcat Capital Management, LLC | 41,324 | 922,000 | 0.15% | ||
| 45 | Swiss National Bank | 40,100 | 895,000 | 0.14% | ||
| 46 | TOCQUEVILLE ASSET MANAGEMENT L.P. | 35,000 | 781,000 | 0.13% | ||
| 47 | GOLDMAN SACHS GROUP INC | 34,559 | 771,000 | 0.12% | ||
| 48 | TD ASSET MANAGEMENT INC | 33,770 | 754,000 | 0.12% | ||
| 49 | CITADEL ADVISORS LLC | 26,800 | 598,000 | 0.10% | Call | |
| 50 | TUDOR INVESTMENT CORP ET AL | 26,185 | 584,000 | 0.09% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
