| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | Nationwide Fund Advisors | 1,670 | 35,000 | 0.03% | ||
| 2 | NORGES BANK | 37,400 | 790,000 | 0.77% | ||
| 3 | MILLENNIUM MANAGEMENT LLC | 78,818 | 1,664,000 | 1.62% | ||
| 4 | PLATINUM INVESTMENT MANAGEMENT LTD | 111,519 | 2,354,000 | 2.29% | ||
| 5 | Iguana Healthcare Management, LLC | 150,000 | 3,167,000 | 3.08% | ||
| 6 | PRICE T ROWE ASSOCIATES INC /MD/ | 398,229 | 8,407,000 | 8.19% | ||
| 7 | Rock Springs Capital Management LP | 400,000 | 8,444,000 | 8.22% | ||
| 8 | Tekla Capital Management LLC | 479,150 | 10,115,000 | 9.85% | ||
| 9 | FRANKLIN RESOURCES INC | 636,328 | 13,433,000 | 13.08% | ||
| 10 | BAKER BROS. ADVISORS LP | 1,160,014 | 24,488,000 | 23.85% | ||
| 11 | Novo Holdings A/S | 1,410,417 | 29,774,000 | 29.00% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
