| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | SEATTLE GENETICS INC | 45,711,856 | 2,412,215,000 | 23.65% | ||
| 2 | INCYTE | 23,499,087 | 2,356,253,000 | 23.10% | ||
| 3 | ALEXION PHARMACEUTIC | 6,543,295 | 800,572,000 | 7.85% | ||
| 4 | ACADIA PHARMACEUTICALS INC COM | 25,819,768 | 744,642,000 | 7.30% | ||
| 5 | Incyte Corporation | 274,500,000 | 558,650,000 | 5.48% | PRN | |
| 6 | Incyte Corporation | 259,000,000 | 518,139,000 | 5.08% | PRN | |
| 7 | GENOMIC HEALTH INC COM | 13,770,302 | 404,709,000 | 3.97% | ||
| 8 | BIOMARIN | 4,806,483 | 398,169,000 | 3.90% | ||
| 9 | DBV TECHNOLOGIES | 5,509,560 | 193,551,000 | 1.90% | ||
| 10 | Aquinox Pharmaceuticals Inc | 10,536,092 | 173,951,000 | 1.71% | ||
| 11 | BEIGENE LTD | 3,673,175 | 111,518,000 | 1.09% | ||
| 12 | ABBVIE INC | 1,685,994 | 105,577,000 | 1.03% | ||
| 13 | BIOMARIN PHARMACEUTICAL INC | 22,379,000 | 90,531,000 | 0.89% | PRN | |
| 14 | BIOCRYST PHARMACEUTICALS | 10,963,944 | 69,402,000 | 0.68% | ||
| 15 | AMARIN CORP PLC | 22,169,509 | 68,282,000 | 0.67% | ||
| 16 | BELLICUM PHARMACEUTICALS INC COM | 4,865,647 | 66,270,000 | 0.65% | ||
| 17 | SPARK THERAPEUTICS INC | 1,318,341 | 65,785,000 | 0.64% | ||
| 18 | ACORDA THERAPEUTICS | 3,301,791 | 62,074,000 | 0.61% | ||
| 19 | ACHAOGEN INC COM | 4,582,382 | 59,663,000 | 0.58% | ||
| 20 | ADVANCED ACCELERATOR APPLIC | 2,167,137 | 57,993,000 | 0.57% | ||
| 21 | INVITAE CORP | 7,288,300 | 57,869,000 | 0.57% | ||
| 22 | CERUS CORP | 13,053,275 | 56,782,000 | 0.56% | ||
| 23 | EXELIXIS INC | 3,003,569 | 44,783,000 | 0.44% | ||
| 24 | NEUROCRINE BIOSCIE COM USD0.001 | 895,422 | 34,653,000 | 0.34% | ||
| 25 | HERON THERAPEUTICS INC | 2,383,569 | 31,225,000 | 0.31% | ||
| 26 | VERSARTIS INC COM | 1,920,845 | 28,621,000 | 0.28% | ||
| 27 | Foamix Pharmaceuticals Ltd. | 2,466,702 | 27,380,000 | 0.27% | ||
| 28 | PROGENICS PHARMACEUTICALS IN | 3,150,808 | 27,223,000 | 0.27% | ||
| 29 | ACORDA THERAPEUTICS INC | 35,083,000 | 26,570,000 | 0.26% | PRN | |
| 30 | MERUS N V | 1,160,014 | 24,488,000 | 0.24% | ||
| 31 | XENCOR INC COM | 872,072 | 22,953,000 | 0.23% | ||
| 32 | ARRAY BIOPHARMA INC COM | 2,585,913 | 22,730,000 | 0.22% | ||
| 33 | BLUEBIRD BIO INCORPORATED | 351,441 | 21,684,000 | 0.21% | ||
| 34 | Ascendis Pharma | 1,023,266 | 20,711,000 | 0.20% | ||
| 35 | DERMA SCIENCES INC COM PAR .01 | 3,752,390 | 19,512,000 | 0.19% | ||
| 36 | AEGERION PHARMACEUTICALS INC | 26,517,000 | 19,103,000 | 0.19% | PRN | |
| 37 | GALAPAGOS NV | 259,894 | 16,683,000 | 0.16% | ||
| 38 | IDERA PHARMACEUTICALS INC | 10,272,314 | 15,408,000 | 0.15% | ||
| 39 | AVEXIS INC COM | 315,300 | 15,049,000 | 0.15% | ||
| 40 | INTELLIA THERAPEUTICS INC | 1,062,120 | 13,924,000 | 0.14% | ||
| 41 | AIMMUNE THERAPEUTICS INC COM | 673,908 | 13,781,000 | 0.14% | ||
| 42 | HALOZYME THERAPEUTICS INC | 1,391,507 | 13,748,000 | 0.13% | ||
| 43 | BIOMARIN PHARMACEUTICAL INC | 12,228,000 | 13,733,000 | 0.13% | PRN | |
| 44 | NEURODERM LTD | 571,667 | 12,691,000 | 0.12% | ||
| 45 | SANGAMO BIOSCIENCES INCORPORATED | 4,055,876 | 12,370,000 | 0.12% | ||
| 46 | AERIE PHARMACEUTICALS INC | 299,356 | 11,331,000 | 0.11% | ||
| 47 | MIRATI THERAPEUTICS INC COM | 2,269,198 | 10,779,000 | 0.11% | ||
| 48 | SAGE THERAPEUTICS | 208,328 | 10,637,000 | 0.10% | ||
| 49 | ZOGENIX INC | 838,809 | 10,192,000 | 0.10% | ||
| 50 | DERMIRA INC | 326,428 | 9,901,000 | 0.10% |
Portfolio data is normalized using SEC Form 13F filings, including the Original 13F-HR (0001144204-17-008836, filed 2017.02.14).
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
