| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | BAUPOST GROUP LLC/MA | 25,000,000 | 41,000,000 | 28.78% | ||
| 2 | BVF INC/IL | 18,799,368 | 30,831,000 | 21.64% | ||
| 3 | NEA Management Company, LLC | 10,750,000 | 17,630,000 | 12.37% | ||
| 4 | FRANKLIN RESOURCES INC | 6,899,600 | 11,315,000 | 7.94% | ||
| 5 | Avoro Capital Advisors LLC | 5,611,323 | 9,203,000 | 6.46% | ||
| 6 | VANGUARD GROUP INC | 3,481,017 | 5,709,000 | 4.01% | ||
| 7 | PERCEPTIVE ADVISORS LLC | 3,414,121 | 5,599,000 | 3.93% | ||
| 8 | BlackRock Fund Advisors | 2,049,811 | 3,362,000 | 2.36% | ||
| 9 | BlackRock Institutional Trust Company, N.A. | 1,849,475 | 3,033,000 | 2.13% | ||
| 10 | DEUTSCHE BANK AG\ | 1,082,942 | 1,775,000 | 1.25% | ||
| 11 | FT OPTIONS LLC | 917,575 | 1,505,000 | 1.06% | ||
| 12 | EverPoint Asset Management, LLC | 800,000 | 1,312,000 | 0.92% | ||
| 13 | GEODE CAPITAL MANAGEMENT, LLC | 679,395 | 1,114,000 | 0.78% | ||
| 14 | Anson Funds Management LP | 637,700 | 1,046,000 | 0.73% | ||
| 15 | MILLENNIUM MANAGEMENT LLC | 440,572 | 723,000 | 0.51% | ||
| 16 | First Eagle Investment Management, LLC | 400,000 | 656,000 | 0.46% | ||
| 17 | GOLDMAN SACHS GROUP INC | 374,506 | 614,000 | 0.43% | ||
| 18 | PERKINS CAPITAL MANAGEMENT INC | 275,300 | 451,000 | 0.32% | ||
| 19 | SHEPHERD KAPLAN KROCHUK, LLC | 261,843 | 429,000 | 0.30% | ||
| 20 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 250,788 | 411,000 | 0.29% | ||
| 21 | SABBY MANAGEMENT, LLC | 238,899 | 392,000 | 0.28% | ||
| 22 | ClariVest Asset Management LLC | 226,066 | 370,000 | 0.26% | ||
| 23 | BLACKROCK ADVISORS LLC | 167,806 | 275,000 | 0.19% | ||
| 24 | CALIFORNIA PUBLIC EMPLOYEES RETIREMENT SYSTEM | 167,000 | 274,000 | 0.19% | ||
| 25 | NORTHERN TRUST CORP | 162,455 | 267,000 | 0.19% | ||
| 26 | Telemetry Investments, L.L.C. | 142,000 | 233,000 | 0.16% | ||
| 27 | Virtu KCG Holdings LLC | 137,775 | 226,000 | 0.16% | ||
| 28 | JACOBS LEVY EQUITY MANAGEMENT, INC | 115,330 | 189,000 | 0.13% | ||
| 29 | Bank of New York Mellon Corp | 107,689 | 176,000 | 0.12% | ||
| 30 | BRIDGEWAY CAPITAL MANAGEMENT, LLC | 105,100 | 172,000 | 0.12% | ||
| 31 | Edge Wealth Management LLC | 100,000 | 164,000 | 0.12% | SH | |
| 32 | Connor, Clark & Lunn Investment Management Ltd. | 95,000 | 156,000 | 0.11% | ||
| 33 | ProShare Advisors LLC | 85,070 | 140,000 | 0.10% | ||
| 34 | STIFEL FINANCIAL CORP | 83,765 | 137,000 | 0.10% | ||
| 35 | OXFORD ASSET MANAGEMENT LLP | 81,293 | 133,000 | 0.09% | ||
| 36 | LADENBURG THALMANN FINANCIAL SERVICES INC. | 80,689 | 133,000 | 0.09% | ||
| 37 | D. E. Shaw & Co., Inc. | 77,800 | 128,000 | 0.09% | ||
| 38 | STATE STREET CORP | 67,140 | 109,000 | 0.08% | ||
| 39 | TWO SIGMA SECURITIES, LLC | 49,828 | 82,000 | 0.06% | ||
| 40 | Tower Research Capital LLC (TRC) | 49,579 | 81,000 | 0.06% | ||
| 41 | TUDOR INVESTMENT CORP ET AL | 48,760 | 80,000 | 0.06% | ||
| 42 | UBS Group AG | 43,300 | 71,000 | 0.05% | ||
| 43 | WOLVERINE TRADING LP /BD | 39,600 | 61,000 | 0.04% | Put | |
| 44 | GROUP ONE TRADING LLC | 36,133 | 59,000 | 0.04% | ||
| 45 | WOLVERINE TRADING LP /BD | 35,788 | 55,000 | 0.04% | ||
| 46 | D.A. DAVIDSON & CO. | 32,200 | 52,000 | 0.04% | ||
| 47 | INTERCONTINENTAL WEALTH ADVISORS, LLC | 29,800 | 49,000 | 0.03% | ||
| 48 | GSA CAPITAL PARTNERS LLP | 29,700 | 49,000 | 0.03% | ||
| 49 | CREDIT SUISSE AG/ | 28,895 | 47,000 | 0.03% | ||
| 50 | CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 25,700 | 43,000 | 0.03% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
