| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | SAREPTA THERAPEUTICS INC | 3,395,236 | 208,506,000 | 13.46% | ||
| 2 | NEUROCRINE BIOSCIE COM USD0.001 | 2,476,272 | 125,398,000 | 8.09% | ||
| 3 | AMICUS THERAPEUTICS INC | 14,116,644 | 104,463,000 | 6.74% | ||
| 4 | TESARO INC | 682,415 | 68,405,000 | 4.42% | ||
| 5 | RETROPHIN INC COM | 2,446,482 | 54,752,000 | 3.53% | ||
| 6 | GLOBAL BLOOD THERAPEUTICS IN COM | 2,334,168 | 53,802,000 | 3.47% | ||
| 7 | VERSARTIS INC COM | 4,028,685 | 49,351,000 | 3.19% | ||
| 8 | NXSTAGE MED INC COM | 1,669,703 | 41,726,000 | 2.69% | ||
| 9 | XENCOR INC COM | 1,496,229 | 36,643,000 | 2.37% | ||
| 10 | LA JOLLA PHARMACEUTICAL CO | 1,323,324 | 31,482,000 | 2.03% | ||
| 11 | Lion Biotechnologies | 3,567,553 | 29,360,000 | 1.90% | ||
| 12 | WAVE LIFE SCIENCES LTD | 683,448 | 22,191,000 | 1.43% | ||
| 13 | ACCELERON PHARMA | 589,890 | 21,348,000 | 1.38% | ||
| 14 | COLUCID PHARMACEUTICALS INC COM | 552,030 | 21,060,000 | 1.36% | ||
| 15 | ACELRX PHARMACEUTICALS INC | 5,408,728 | 21,040,000 | 1.36% | ||
| 16 | QUOTIENT LTD | 2,671,794 | 20,893,000 | 1.35% | ||
| 17 | DBV TECHNOLOGIES | 563,268 | 20,464,000 | 1.32% | ||
| 18 | CORBUS PHARMACEUTICALS HLDGS COM | 2,701,023 | 18,339,000 | 1.18% | ||
| 19 | REGENXBIO INC COM | 1,282,286 | 17,964,000 | 1.16% | ||
| 20 | RADIUS HEALTH | 313,502 | 16,957,000 | 1.09% | ||
| 21 | FLAMEL TECHNOLOGIES SA SPONSORED ADR | 1,363,711 | 16,910,000 | 1.09% | ||
| 22 | KADMON HLDGS INC | 2,209,657 | 16,218,000 | 1.05% | ||
| 23 | DEXCOM | 178,849 | 15,678,000 | 1.01% | ||
| 24 | AERIE PHARMACEUTICALS INC | 406,771 | 15,352,000 | 0.99% | ||
| 25 | ALDEYRA THERAPEUTICS INC | 1,940,458 | 15,174,000 | 0.98% | ||
| 26 | ARDELYX INC COM | 1,057,257 | 13,680,000 | 0.88% | ||
| 27 | BLUEPRINT MEDICINES CORP COM | 460,024 | 13,662,000 | 0.88% | ||
| 28 | DEPOMED INC | 535,000 | 13,370,000 | 0.86% | ||
| 29 | ALDER BIOPHARMACEUTICALS INC | 391,280 | 12,822,000 | 0.83% | ||
| 30 | Foamix Pharmaceuticals Ltd. | 1,373,284 | 12,717,000 | 0.82% | ||
| 31 | CYTOMX THERAPEUTICS, INC | 742,021 | 11,634,000 | 0.75% | ||
| 32 | MINERVA NEUROSCIENCES INC COM | 810,537 | 11,440,000 | 0.74% | ||
| 33 | ZYNERBA PHARMACEUTICALS INC | 868,897 | 11,339,000 | 0.73% | ||
| 34 | DERMIRA INC | 331,610 | 11,215,000 | 0.72% | ||
| 35 | Clearside Biomedical Inc | 634,801 | 11,013,000 | 0.71% | ||
| 36 | ACLARIS THERAPEUTICS INC COM | 430,000 | 11,012,000 | 0.71% | ||
| 37 | Evolent Health, Inc. | 428,284 | 10,544,000 | 0.68% | ||
| 38 | VBI VACCINES INC COM NEW | 3,058,433 | 10,490,000 | 0.68% | ||
| 39 | MYOKARDIA INC | 634,894 | 10,374,000 | 0.67% | ||
| 40 | UNIQURE NV | 1,312,836 | 10,043,000 | 0.65% | ||
| 41 | VERTEX PHARMACEUT | 107,000 | 9,331,000 | 0.60% | ||
| 42 | ANI PHARMACEUTICALS INC | 7,500,000 | 9,279,000 | 0.60% | PRN | |
| 43 | CIDARA THERAPEUTICS INC | 773,369 | 8,855,000 | 0.57% | ||
| 44 | FIVE PRIME THERAPEUTICS INC | 166,509 | 8,740,000 | 0.56% | ||
| 45 | FORWARD PHARMA A/S | 404,472 | 8,494,000 | 0.55% | ||
| 46 | PFENEX INC COM | 939,930 | 8,412,000 | 0.54% | ||
| 47 | ABIOMED INC | 63,290 | 8,138,000 | 0.53% | ||
| 48 | ABEONA THERAPEUTICS INC | 1,336,050 | 8,016,000 | 0.52% | ||
| 49 | AVEXIS INC COM | 190,000 | 7,830,000 | 0.51% | ||
| 50 | PSIVIDA CORP | 2,552,431 | 7,683,000 | 0.50% |
Portfolio data is normalized using SEC Form 13F filings, including the Original 13F-HR (0001019056-16-001648, filed 2016.11.14).
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
