| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | FMR LLC | 2,595,058 | 135,747,000 | 12.48% | ||
| 2 | WELLINGTON MANAGEMENT GROUP LLP | 2,322,210 | 121,474,000 | 11.17% | ||
| 3 | ADAGE CAPITAL PARTNERS GP, L.L.C. | 1,722,969 | 90,128,000 | 8.29% | ||
| 4 | Capital World Investors | 1,702,799 | 89,073,000 | 8.19% | ||
| 5 | Bank of New York Mellon Corp | 1,502,023 | 78,570,000 | 7.22% | ||
| 6 | VANGUARD GROUP INC | 1,118,977 | 58,534,000 | 5.38% | ||
| 7 | ALLIANCEBERNSTEIN L.P. | 1,048,120 | 54,827,000 | 5.04% | ||
| 8 | JANUS HENDERSON INVESTORS US LLC | 1,003,675 | 52,502,000 | 4.83% | ||
| 9 | PRICE T ROWE ASSOCIATES INC /MD/ | 589,321 | 30,827,000 | 2.83% | ||
| 10 | FRANKLIN RESOURCES INC | 492,184 | 25,746,000 | 2.37% | ||
| 11 | UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 472,573 | 24,721,000 | 2.27% | ||
| 12 | BlackRock Fund Advisors | 457,057 | 23,909,000 | 2.20% | ||
| 13 | BlackRock Institutional Trust Company, N.A. | 439,458 | 22,988,000 | 2.11% | ||
| 14 | Point72 Asset Management, L.P. | 333,800 | 17,461,000 | 1.61% | ||
| 15 | STATE STREET CORP | 313,858 | 16,419,000 | 1.51% | ||
| 16 | EverPoint Asset Management, LLC | 290,000 | 15,170,000 | 1.39% | ||
| 17 | Rock Springs Capital Management LP | 273,000 | 14,281,000 | 1.31% | ||
| 18 | Palo Alto Investors LP | 243,868 | 12,757,000 | 1.17% | ||
| 19 | Broadfin Capital, LLC | 239,675 | 12,537,000 | 1.15% | ||
| 20 | LMCG INVESTMENTS, LLC | 230,335 | 12,049,000 | 1.11% | ||
| 21 | SECTORAL ASSET MANAGEMENT INC | 224,580 | 11,748,000 | 1.08% | ||
| 22 | NORTHERN TRUST CORP | 224,263 | 11,731,000 | 1.08% | ||
| 23 | Engaged Capital LLC | 206,469 | 10,800,000 | 0.99% | ||
| 24 | CREDIT SUISSE AG/ | 204,824 | 10,713,000 | 0.99% | ||
| 25 | CITADEL ADVISORS LLC | 144,102 | 7,538,000 | 0.69% | ||
| 26 | DEERFIELD MANAGEMENT COMPANY, L.P. | 134,200 | 7,020,000 | 0.65% | ||
| 27 | GOLDMAN SACHS GROUP INC | 122,500 | 6,408,000 | 0.59% | Put | |
| 28 | JPMORGAN CHASE & CO | 108,216 | 5,661,000 | 0.52% | ||
| 29 | GEODE CAPITAL MANAGEMENT, LLC | 104,993 | 5,492,000 | 0.50% | ||
| 30 | TWO SIGMA ADVISERS, LP | 83,651 | 4,712,000 | 0.43% | ||
| 31 | Ghost Tree Capital, LLC | 90,000 | 4,708,000 | 0.43% | ||
| 32 | Asset Management One Co., Ltd. | 92,849 | 4,689,000 | 0.43% | ||
| 33 | Rhenman & Partners Asset Management AB | 87,000 | 4,551,000 | 0.42% | ||
| 34 | TIAA CREF INVESTMENT MANAGEMENT LLC | 70,828 | 3,705,000 | 0.34% | ||
| 35 | PRUDENTIAL FINANCIAL INC | 65,764 | 3,440,000 | 0.32% | ||
| 36 | Numeric Investors LLC | 61,900 | 3,238,000 | 0.30% | ||
| 37 | AXA S.A. | 61,610 | 3,223,000 | 0.30% | ||
| 38 | PDT Partners, LLC | 60,793 | 3,180,000 | 0.29% | ||
| 39 | STATE FARM MUTUAL AUTOMOBILE INSURANCE CO | 58,800 | 3,076,000 | 0.28% | ||
| 40 | BlackRock Investment Management, LLC | 58,480 | 3,059,000 | 0.28% | ||
| 41 | CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 52,171 | 2,730,000 | 0.25% | ||
| 42 | BELLEVUE ASSET MANAGEMENT AG | 45,000 | 2,354,000 | 0.22% | ||
| 43 | Employees Retirement System of Texas | 45,000 | 2,354,000 | 0.22% | ||
| 44 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 41,100 | 2,150,000 | 0.20% | Put | |
| 45 | NORGES BANK | 39,948 | 2,090,000 | 0.19% | ||
| 46 | NICHOLAS COMPANY, INC. | 39,265 | 2,053,000 | 0.19% | ||
| 47 | MACQUARIE GROUP LTD | 38,408 | 2,009,000 | 0.18% | ||
| 48 | MARINER INVESTMENT GROUP LLC | 35,000 | 1,831,000 | 0.17% | ||
| 49 | Pentwater Capital Management LP | 35,000 | 1,831,000 | 0.17% | ||
| 50 | CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 31,518 | 1,649,000 | 0.15% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
