| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | Consonance Capital Management LP | 1,056,289 | 41,734,000 | 14.59% | ||
| 2 | BlackRock Fund Advisors | 643,971 | 25,443,000 | 8.89% | ||
| 3 | STATE STREET CORP | 635,023 | 25,095,000 | 8.77% | ||
| 4 | VANGUARD GROUP INC | 341,180 | 13,481,000 | 4.71% | ||
| 5 | Healthcare Value Capital, LLC | 315,000 | 12,446,000 | 4.35% | ||
| 6 | SENZAR ASSET MANAGEMENT, LLC | 270,040 | 10,669,280 | 3.73% | ||
| 7 | GLENMEDE TRUST CO NA | 239,113 | 9,445,000 | 3.30% | ||
| 8 | WELLS FARGO & COMPANY/MN | 235,894 | 9,320,000 | 3.26% | ||
| 9 | Allianz Asset Management GmbH | 216,141 | 8,540,000 | 2.98% | ||
| 10 | BlackRock Institutional Trust Company, N.A. | 187,114 | 7,393,000 | 2.58% | ||
| 11 | DEUTSCHE BANK AG\ | 173,363 | 6,848,000 | 2.39% | ||
| 12 | NOMURA HOLDINGS INC | 162,513 | 6,481,000 | 2.27% | ||
| 13 | OBERWEIS ASSET MANAGEMENT INC/ | 158,235 | 6,252,000 | 2.19% | ||
| 14 | Apex Capital Management | 150,845 | 5,960,000 | 2.08% | ||
| 15 | Century Capital Management, LLC | 123,356 | 4,874,000 | 1.70% | ||
| 16 | PUBLIC EMPLOYEES RETIREMENT SYSTEM OF OHIO | 108,300 | 4,279,000 | 1.50% | ||
| 17 | Bank of New York Mellon Corp | 104,053 | 4,112,000 | 1.44% | ||
| 18 | ALPS ADVISORS INC | 9,381 | 3,706,000 | 1.30% | ||
| 19 | NORTHERN TRUST CORP | 91,019 | 3,596,000 | 1.26% | ||
| 20 | ACADIAN ASSET MANAGEMENT LLC | 79,611 | 3,145,000 | 1.10% | ||
| 21 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 78,000 | 3,082,000 | 1.08% | Put | |
| 22 | BANK OF AMERICA CORP /DE/ | 76,133 | 3,008,000 | 1.05% | ||
| 23 | FORESTERS INVESTMENT MANAGEMENT COMPANY, INC. | 75,500 | 2,983,000 | 1.04% | ||
| 24 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 74,900 | 2,959,000 | 1.03% | Call | |
| 25 | AMERIPRISE FINANCIAL INC | 64,110 | 2,533,000 | 0.89% | ||
| 26 | RUSSELL FRANK CO/ | 61,945 | 2,447,000 | 0.86% | ||
| 27 | THIRD AVENUE MANAGEMENT LLC | 59,716 | 2,359,000 | 0.82% | ||
| 28 | Trexquant Investment LP | 59,346 | 2,344,000 | 0.82% | ||
| 29 | Timpani Capital Management LLC | 55,582 | 2,196,000 | 0.77% | ||
| 30 | GEODE CAPITAL MANAGEMENT, LLC | 52,648 | 2,079,000 | 0.73% | ||
| 31 | GSA CAPITAL PARTNERS LLP | 50,027 | 1,977,000 | 0.69% | ||
| 32 | PRINCIPAL FINANCIAL GROUP INC | 47,624 | 1,882,000 | 0.66% | ||
| 33 | CALIFORNIA PUBLIC EMPLOYEES RETIREMENT SYSTEM | 41,400 | 1,636,000 | 0.57% | ||
| 34 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 40,223 | 1,589,000 | 0.56% | ||
| 35 | MILLENNIUM MANAGEMENT LLC | 40,173 | 1,587,000 | 0.55% | ||
| 36 | SG Americas Securities, LLC | 39,566 | 1,563,000 | 0.55% | ||
| 37 | TIAA CREF INVESTMENT MANAGEMENT LLC | 36,038 | 1,424,000 | 0.50% | ||
| 38 | JW Asset Management, LLC | 35,864 | 1,417,000 | 0.50% | ||
| 39 | WHITEBOX ADVISORS LLC | 32,981 | 1,303,000 | 0.46% | ||
| 40 | FIRST TRUST ADVISORS LP | 32,281 | 1,275,000 | 0.45% | ||
| 41 | BlackRock Investment Management, LLC | 31,160 | 1,231,000 | 0.43% | ||
| 42 | Sarissa Capital Management LP | 31,000 | 1,225,000 | 0.43% | ||
| 43 | MUTUAL OF AMERICA CAPITAL MANAGEMENT LLC | 30,000 | 1,185,000 | 0.41% | ||
| 44 | SCHOLTZ & COMPANY, LLC | 28,080 | 1,109,000 | 0.39% | ||
| 45 | NEW YORK STATE TEACHERS RETIREMENT SYSTEM | 27,372 | 1,081,000 | 0.38% | ||
| 46 | CITADEL ADVISORS LLC | 25,337 | 1,001,000 | 0.35% | ||
| 47 | Healthcare Value Capital, LLC | 25,000 | 988,000 | 0.35% | Call | |
| 48 | Invesco Ltd. | 24,977 | 987,000 | 0.34% | ||
| 49 | Gotham Asset Management, LLC | 24,801 | 980,000 | 0.34% | ||
| 50 | Spot Trading L.L.C | 23,600 | 932,000 | 0.33% | Call |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
