| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | Consonance Capital Management LP | 1,055,791 | 65,512,000 | 15.68% | ||
| 2 | STATE STREET CORP | 708,487 | 43,961,000 | 10.52% | ||
| 3 | BlackRock Fund Advisors | 631,656 | 39,194,000 | 9.38% | ||
| 4 | VANGUARD GROUP INC | 342,495 | 21,253,000 | 5.09% | ||
| 5 | PERCEPTIVE ADVISORS LLC | 327,157 | 20,300,000 | 4.86% | ||
| 6 | BlackRock Institutional Trust Company, N.A. | 247,959 | 15,386,000 | 3.68% | ||
| 7 | WELLS FARGO & COMPANY/MN | 221,500 | 13,743,000 | 3.29% | ||
| 8 | Allianz Asset Management GmbH | 213,562 | 13,252,000 | 3.17% | ||
| 9 | Timpani Capital Management LLC | 145,818 | 9,048,000 | 2.17% | ||
| 10 | NOMURA HOLDINGS INC | 151,497 | 9,007,000 | 2.16% | ||
| 11 | OBERWEIS ASSET MANAGEMENT INC/ | 144,785 | 8,984,000 | 2.15% | ||
| 12 | Apex Capital Management | 137,308 | 8,520,000 | 2.04% | ||
| 13 | Healthcare Value Capital, LLC | 125,000 | 7,756,000 | 1.86% | ||
| 14 | DEUTSCHE BANK AG\ | 123,289 | 7,649,000 | 1.83% | ||
| 15 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 115,900 | 7,192,000 | 1.72% | Call | |
| 16 | FORESTERS INVESTMENT MANAGEMENT COMPANY, INC. | 99,250 | 6,158,000 | 1.47% | ||
| 17 | PUBLIC EMPLOYEES RETIREMENT SYSTEM OF OHIO | 84,700 | 5,256,000 | 1.26% | ||
| 18 | Bank of New York Mellon Corp | 80,972 | 5,024,000 | 1.20% | ||
| 19 | NORTHERN TRUST CORP | 80,375 | 4,987,000 | 1.19% | ||
| 20 | TEACHERS ADVISORS, LLC | 75,002 | 4,654,000 | 1.11% | ||
| 21 | Century Capital Management, LLC | 73,803 | 4,579,000 | 1.10% | ||
| 22 | AMERIPRISE FINANCIAL INC | 66,637 | 4,134,000 | 0.99% | ||
| 23 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 63,100 | 3,915,000 | 0.94% | Put | |
| 24 | RUSSELL FRANK CO/ | 56,276 | 3,492,000 | 0.84% | ||
| 25 | FMR LLC | 55,700 | 3,456,000 | 0.83% | ||
| 26 | FIRST TRUST ADVISORS LP | 55,618 | 3,451,000 | 0.83% | ||
| 27 | THIRD AVENUE MANAGEMENT LLC | 51,790 | 3,214,000 | 0.77% | ||
| 28 | GEODE CAPITAL MANAGEMENT, LLC | 51,003 | 3,164,000 | 0.76% | ||
| 29 | PRINCIPAL FINANCIAL GROUP INC | 50,064 | 3,106,000 | 0.74% | ||
| 30 | CALIFORNIA PUBLIC EMPLOYEES RETIREMENT SYSTEM | 46,189 | 2,866,000 | 0.69% | ||
| 31 | MANAGED ACCOUNT ADVISORS LLC | 44,794 | 2,779,000 | 0.67% | ||
| 32 | Spot Trading L.L.C | 39,000 | 2,420,000 | 0.58% | Call | |
| 33 | SG Americas Securities, LLC | 37,210 | 2,309,000 | 0.55% | ||
| 34 | TIAA CREF INVESTMENT MANAGEMENT LLC | 36,783 | 2,282,000 | 0.55% | ||
| 35 | AQR CAPITAL MANAGEMENT LLC | 36,024 | 2,236,000 | 0.54% | ||
| 36 | JW Asset Management, LLC | 35,864 | 2,225,000 | 0.53% | ||
| 37 | BlackRock Investment Management, LLC | 31,677 | 1,966,000 | 0.47% | ||
| 38 | Sarissa Capital Management LP | 31,000 | 1,924,000 | 0.46% | ||
| 39 | GOLDMAN SACHS GROUP INC | 29,061 | 1,803,000 | 0.43% | ||
| 40 | MILLENNIUM MANAGEMENT LLC | 27,299 | 1,694,000 | 0.41% | ||
| 41 | GSA CAPITAL PARTNERS LLP | 27,202 | 1,688,000 | 0.40% | ||
| 42 | NEW YORK STATE TEACHERS RETIREMENT SYSTEM | 26,672 | 1,655,000 | 0.40% | ||
| 43 | Jefferies Group LLC | 24,200 | 1,502,000 | 0.36% | Call | |
| 44 | CREDIT SUISSE AG/ | 24,015 | 1,490,000 | 0.36% | ||
| 45 | MUTUAL OF AMERICA CAPITAL MANAGEMENT LLC | 22,000 | 1,365,000 | 0.33% | ||
| 46 | Invesco Ltd. | 21,698 | 1,346,000 | 0.32% | ||
| 47 | PRUDENTIAL FINANCIAL INC | 19,030 | 1,181,000 | 0.28% | ||
| 48 | Airain ltd | 18,961 | 1,177,000 | 0.28% | ||
| 49 | CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 17,728 | 1,101,000 | 0.26% | ||
| 50 | Cubist Systematic Strategies, LLC | 17,100 | 1,061,000 | 0.25% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
