| 1 |
BAUPOST GROUP LLC/MA |
4,166,666 |
17,958,000 |
28.26% |
|
|
| 2 |
BVF INC/IL |
3,133,224 |
13,504,000 |
21.25% |
|
|
| 3 |
NEA Management Company, LLC |
1,791,666 |
7,722,000 |
12.15% |
|
|
| 4 |
FRANKLIN RESOURCES INC |
1,113,166 |
4,798,000 |
7.55% |
|
|
| 5 |
Avoro Capital Advisors LLC |
921,248 |
3,971,000 |
6.25% |
|
|
| 6 |
VANGUARD GROUP INC |
657,118 |
2,832,000 |
4.46% |
|
|
| 7 |
PERCEPTIVE ADVISORS LLC |
546,498 |
2,355,000 |
3.71% |
|
|
| 8 |
SANDIA HOLDINGS, LLC |
543,719 |
2,343,000 |
3.69% |
|
|
| 9 |
BlackRock Institutional Trust Company, N.A. |
308,243 |
1,329,000 |
2.09% |
|
|
| 10 |
Anson Funds Management LP |
229,286 |
988,000 |
1.55% |
|
|
| 11 |
DEUTSCHE BANK AG\ |
214,687 |
925,000 |
1.46% |
|
|
| 12 |
FT OPTIONS LLC |
177,829 |
766,000 |
1.21% |
|
|
| 13 |
OXFORD ASSET MANAGEMENT LLP |
122,075 |
526,000 |
0.83% |
|
|
| 14 |
GEODE CAPITAL MANAGEMENT, LLC |
115,584 |
498,000 |
0.78% |
|
|
| 15 |
HANDELSBANKEN FONDER AB |
84,000 |
362,000 |
0.57% |
|
|
| 16 |
SUSQUEHANNA INTERNATIONAL GROUP, LLP |
47,772 |
206,000 |
0.32% |
|
|
| 17 |
MILLENNIUM MANAGEMENT LLC |
47,136 |
203,000 |
0.32% |
|
|
| 18 |
BlackRock Fund Advisors |
46,366 |
200,000 |
0.31% |
|
|
| 19 |
PERKINS CAPITAL MANAGEMENT INC |
45,242 |
195,000 |
0.31% |
|
|
| 20 |
Virtu KCG Holdings LLC |
34,363 |
148,000 |
0.23% |
|
|
| 21 |
SUSQUEHANNA INTERNATIONAL GROUP, LLP |
32,200 |
139,000 |
0.22% |
Call |
|
| 22 |
Bank of New York Mellon Corp |
28,401 |
122,000 |
0.19% |
|
|
| 23 |
NORTHERN TRUST CORP |
28,057 |
121,000 |
0.19% |
|
|
| 24 |
CALIFORNIA PUBLIC EMPLOYEES RETIREMENT SYSTEM |
27,832 |
120,000 |
0.19% |
|
|
| 25 |
SHEPHERD KAPLAN KROCHUK, LLC |
26,561 |
114,000 |
0.18% |
|
|
| 26 |
BLACKROCK ADVISORS LLC |
25,806 |
111,000 |
0.17% |
|
|
| 27 |
First Eagle Investment Management, LLC |
24,999 |
108,000 |
0.17% |
|
|
| 28 |
Telemetry Investments, L.L.C. |
21,500 |
93,000 |
0.15% |
|
|
| 29 |
GOLDMAN SACHS GROUP INC |
20,097 |
87,000 |
0.14% |
|
|
| 30 |
Edge Wealth Management LLC |
20,000 |
85,000 |
0.13% |
|
|
| 31 |
BRIDGEWAY CAPITAL MANAGEMENT, LLC |
17,515 |
75,000 |
0.12% |
|
|
| 32 |
Trexquant Investment LP |
16,283 |
70,000 |
0.11% |
|
|
| 33 |
SUSQUEHANNA INTERNATIONAL GROUP, LLP |
14,800 |
64,000 |
0.10% |
Put |
|
| 34 |
STIFEL FINANCIAL CORP |
13,960 |
60,000 |
0.09% |
|
|
| 35 |
LADENBURG THALMANN FINANCIAL SERVICES INC. |
13,446 |
58,000 |
0.09% |
|
|
| 36 |
D. E. Shaw & Co., Inc. |
12,963 |
56,000 |
0.09% |
|
|
| 37 |
ACROSPIRE INVESTMENT MANAGEMENT LLC |
11,284 |
49,000 |
0.08% |
|
|
| 38 |
Paloma Partners Management Co |
10,858 |
47,000 |
0.07% |
|
|
| 39 |
STATE STREET CORP |
11,189 |
47,000 |
0.07% |
|
|
| 40 |
D.A. DAVIDSON & CO. |
5,698 |
24,000 |
0.04% |
|
|
| 41 |
BlackRock Investment Management, LLC |
3,197 |
14,000 |
0.02% |
|
|
| 42 |
GROUP ONE TRADING LLC |
2,885 |
12,000 |
0.02% |
|
|
| 43 |
BARCLAYS PLC |
1,992 |
9,000 |
0.01% |
|
|
| 44 |
BANK OF AMERICA CORP /DE/ |
1,553 |
7,000 |
0.01% |
|
|
| 45 |
MORGAN STANLEY |
1,226 |
5,000 |
0.01% |
|
|
| 46 |
ROYAL BANK OF CANADA |
1,006 |
4,000 |
0.01% |
|
|
| 47 |
FT OPTIONS LLC |
10,800 |
3,000 |
0.00% |
Call |
|
| 48 |
MANUFACTURERS LIFE INSURANCE COMPANY, THE |
588 |
3,000 |
0.00% |
|
|
| 49 |
WELLS FARGO & COMPANY/MN |
539 |
2,000 |
0.00% |
|
|
| 50 |
BANK OF MONTREAL /CAN/ |
225 |
1,000 |
0.00% |
|
|
