| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | CELGENE CORP | 181,722 | 21,042,000 | 9.48% | ||
| 2 | BIOGEN INC | 65,908 | 18,693,000 | 8.42% | ||
| 3 | ALEXION PHARMACEUTIC | 133,841 | 16,375,000 | 7.38% | ||
| 4 | SHIRE PLC | 95,200 | 16,220,000 | 7.31% | ||
| 5 | TESARO INC | 94,500 | 12,705,000 | 5.72% | ||
| 6 | GILEAD SCIENCES INC | 175,784 | 12,590,000 | 5.67% | ||
| 7 | REGENERON PHARMACEUTICALS | 32,430 | 11,910,000 | 5.37% | ||
| 8 | AMGEN INC | 80,104 | 11,714,000 | 5.28% | ||
| 9 | ARIAD PHARMACEUTICALS INC | 657,912 | 8,184,000 | 3.69% | ||
| 10 | INCYTE | 78,775 | 7,898,000 | 3.56% | ||
| 11 | VERTEX PHARMACEUT | 105,522 | 7,780,000 | 3.50% | ||
| 12 | ENTELLUS MEDICAL INC | 403,320 | 7,631,000 | 3.44% | ||
| 13 | ILLUMINA INC | 55,941 | 7,162,000 | 3.23% | ||
| 14 | BIOMARIN | 75,666 | 6,267,000 | 2.82% | ||
| 15 | AERIE PHARMACEUTICALS INC | 138,000 | 5,210,000 | 2.35% | ||
| 16 | CLOVIS ONCOLOGY INC | 75,000 | 3,332,000 | 1.50% | ||
| 17 | INTERCEPT PHARMACEUTICAL | 29,555 | 3,211,000 | 1.45% | ||
| 18 | ADAMAS PHARMACEUTICALS INC | 185,234 | 3,130,000 | 1.41% | ||
| 19 | LIGAND PHARMACEUTICALS INC | 30,000 | 3,048,000 | 1.37% | ||
| 20 | EXELIXIS INC | 185,000 | 2,758,000 | 1.24% | ||
| 21 | Foamix Pharmaceuticals Ltd. | 197,838 | 2,196,000 | 0.99% | ||
| 22 | KALVISTA PHARMACEUTICALS INC | 322,436 | 2,186,000 | 0.98% | ||
| 23 | VANDA PHARMACEUTICALS INC COM | 135,817 | 2,166,000 | 0.98% | ||
| 24 | PROTHENA CORP PLC | 42,000 | 2,066,000 | 0.93% | ||
| 25 | JAZZ PHARMACEUTICALS PLC SHS USD | 18,200 | 1,984,000 | 0.89% | ||
| 26 | SYNERGY PHARMACEUTICALS DEL COM NEW | 312,000 | 1,900,000 | 0.86% | ||
| 27 | ALDER BIOPHARMACEUTICALS INC | 80,000 | 1,664,000 | 0.75% | ||
| 28 | KITE PHARMA INCORPORATED | 36,500 | 1,637,000 | 0.74% | ||
| 29 | NEUROCRINE BIOSCIE COM USD0.001 | 40,264 | 1,558,000 | 0.70% | ||
| 30 | ACADIA PHARMACEUTICALS INC COM | 50,458 | 1,455,000 | 0.66% | ||
| 31 | NEURODERM LTD | 65,000 | 1,437,000 | 0.65% | ||
| 32 | HORIZON PHARMA PLC | 85,000 | 1,374,000 | 0.62% | ||
| 33 | DERMIRA INC | 45,000 | 1,364,000 | 0.61% | ||
| 34 | XENCOR INC COM | 48,000 | 1,263,000 | 0.57% | ||
| 35 | TRILLIUM THERAPEUTICS INC | 221,847 | 1,253,000 | 0.56% | ||
| 36 | TRANSENTERIX INC | 889,082 | 1,156,000 | 0.52% | ||
| 37 | MACROGENICS INC | 54,000 | 1,103,000 | 0.50% | ||
| 38 | IRONWOOD PHARMACEUTICALS INC COM CL A | 59,000 | 903,000 | 0.41% | ||
| 39 | SAGE THERAPEUTICS | 16,996 | 867,000 | 0.39% | ||
| 40 | GW PHARMACEUTICALS PLC | 7,500 | 838,000 | 0.38% | ||
| 41 | RADIUS HEALTH | 19,799 | 753,000 | 0.34% | ||
| 42 | NEKTAR THERAPEUTICS COM | 60,000 | 736,000 | 0.33% | ||
| 43 | SAREPTA THERAPEUTICS INC | 21,000 | 576,000 | 0.26% | ||
| 44 | HALOZYME THERAPEUTICS INC | 58,000 | 572,000 | 0.26% | ||
| 45 | ARRAY BIOPHARMA INC COM | 65,000 | 571,000 | 0.26% | ||
| 46 | ACCELERON PHARMA | 18,606 | 475,000 | 0.21% | ||
| 47 | ACORDA THERAPEUTICS | 22,000 | 414,000 | 0.19% | ||
| 48 | ADAPTIMMUNE THERAPEUTICS PLC | 96,419 | 387,000 | 0.17% | ||
| 49 | AMICUS THERAPEUTICS INC | 55,000 | 273,000 | 0.12% |
Portfolio data is normalized using SEC Form 13F filings, including the Original 13F-HR (0000950123-18-002802, filed 2018.03.02).
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
