| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | Capital World Investors | 3,469,800 | 154,857,000 | 9.32% | ||
| 2 | ORBIMED ADVISORS LLC | 2,562,900 | 114,382,000 | 6.89% | ||
| 3 | VANGUARD GROUP INC | 1,880,162 | 83,912,000 | 5.05% | ||
| 4 | ALLIANCEBERNSTEIN L.P. | 1,870,310 | 83,472,000 | 5.03% | ||
| 5 | JENNISON ASSOCIATES LLC | 1,626,157 | 72,575,000 | 4.37% | ||
| 6 | DIMENSIONAL FUND ADVISORS LP | 1,614,732 | 72,065,000 | 4.34% | ||
| 7 | BlackRock Fund Advisors | 1,593,893 | 71,135,000 | 4.28% | ||
| 8 | FMR LLC | 1,528,883 | 68,234,000 | 4.11% | ||
| 9 | BANK OF AMERICA CORP /DE/ | 862,879 | 38,511,000 | 2.32% | ||
| 10 | FRED ALGER MANAGEMENT, LLC | 782,525 | 34,924,000 | 2.10% | ||
| 11 | JPMORGAN CHASE & CO | 762,344 | 34,024,000 | 2.05% | ||
| 12 | NEXT CENTURY GROWTH INVESTORS LLC | 758,813 | 33,865,000 | 2.04% | ||
| 13 | BlackRock Institutional Trust Company, N.A. | 746,832 | 33,331,000 | 2.01% | ||
| 14 | MILLENNIUM MANAGEMENT LLC | 703,592 | 31,401,000 | 1.89% | ||
| 15 | STATE STREET CORP | 661,233 | 29,512,000 | 1.78% | ||
| 16 | AMERIPRISE FINANCIAL INC | 646,570 | 28,857,000 | 1.74% | ||
| 17 | MUNDER CAPITAL MANAGEMENT | 614,786 | 27,438,000 | 1.65% | ||
| 18 | WELLINGTON MANAGEMENT GROUP LLP | 598,150 | 26,696,000 | 1.61% | ||
| 19 | Herring Creek Capital Management, LLC | 526,928 | 23,517,000 | 1.42% | ||
| 20 | CHARTWELL INVESTMENT PARTNERS, LLC | 430,931 | 19,232,000 | 1.16% | ||
| 21 | PFM Health Sciences, LP | 426,202 | 19,021,000 | 1.15% | ||
| 22 | DEUTSCHE BANK AG\ | 421,272 | 18,799,000 | 1.13% | ||
| 23 | NORTHERN TRUST CORP | 378,293 | 16,883,000 | 1.02% | ||
| 24 | CREDIT SUISSE AG/ | 358,797 | 16,013,000 | 0.96% | ||
| 25 | BNP PARIBAS FINANCIAL MARKETS | 353,843 | 15,792,014 | 0.95% | ||
| 26 | DECADE CAPITAL MANAGEMENT LLC | 350,422 | 15,639,000 | 0.94% | ||
| 27 | Bank of New York Mellon Corp | 335,197 | 14,961,000 | 0.90% | ||
| 28 | Visium Asset Management, LP | 325,143 | 14,511,000 | 0.87% | ||
| 29 | JACOBS LEVY EQUITY MANAGEMENT, INC | 323,277 | 14,428,000 | 0.87% | ||
| 30 | NORGES BANK | 318,172 | 14,200,000 | 0.85% | ||
| 31 | ROTHSCHILD & CO ASSET MANAGEMENT US INC. | 317,809 | 14,184,000 | 0.85% | ||
| 32 | EARNEST PARTNERS LLC | 312,833 | 13,962,000 | 0.84% | ||
| 33 | PAR CAPITAL MANAGEMENT INC | 300,000 | 13,389,000 | 0.81% | ||
| 34 | NOMURA HOLDINGS INC | 275,020 | 12,268,000 | 0.74% | ||
| 35 | DALTON GREINER HARTMAN MAHER & CO | 272,932 | 12,181,000 | 0.73% | ||
| 36 | Tekla Capital Management LLC | 212,541 | 9,486,000 | 0.57% | ||
| 37 | PALISADE CAPITAL MANAGEMENT, LP | 210,047 | 9,374,000 | 0.56% | ||
| 38 | TWO SIGMA INVESTMENTS, LP | 201,843 | 9,008,000 | 0.54% | ||
| 39 | GEODE CAPITAL MANAGEMENT, LLC | 192,073 | 8,572,000 | 0.52% | ||
| 40 | PANAGORA ASSET MANAGEMENT INC | 181,549 | 8,103,000 | 0.49% | ||
| 41 | PRINCIPAL FINANCIAL GROUP INC | 180,595 | 8,059,000 | 0.49% | ||
| 42 | CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 180,394 | 8,051,000 | 0.48% | ||
| 43 | TIAA CREF INVESTMENT MANAGEMENT LLC | 172,823 | 7,713,000 | 0.46% | ||
| 44 | RENAISSANCE TECHNOLOGIES LLC | 169,950 | 7,585,000 | 0.46% | ||
| 45 | ACADIAN ASSET MANAGEMENT LLC | 165,324 | 7,379,000 | 0.44% | ||
| 46 | THRIVENT FINANCIAL FOR LUTHERANS | 163,800 | 7,311,000 | 0.44% | ||
| 47 | Commonwealth Equity Services, Inc | 162,301 | 7,243,000 | 0.44% | ||
| 48 | RUSSELL FRANK CO/ | 170,807 | 7,223,000 | 0.43% | ||
| 49 | BUCKINGHAM CAPITAL MANAGEMENT INC | 158,350 | 7,067,000 | 0.43% | ||
| 50 | Cupps Capital Management, LLC | 156,989 | 7,006,000 | 0.42% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
