| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | Capital World Investors | 3,898,100 | 268,384,000 | 7.92% | ||
| 2 | ORBIMED ADVISORS LLC | 3,236,300 | 222,819,000 | 6.57% | ||
| 3 | VANGUARD GROUP INC | 3,112,789 | 214,315,000 | 6.32% | ||
| 4 | BlackRock Fund Advisors | 2,118,712 | 145,873,000 | 4.30% | ||
| 5 | JENNISON ASSOCIATES LLC | 1,859,887 | 128,053,000 | 3.78% | ||
| 6 | DIMENSIONAL FUND ADVISORS LP | 1,650,632 | 113,643,000 | 3.35% | ||
| 7 | EARNEST PARTNERS LLC | 1,455,258 | 100,195,000 | 2.96% | ||
| 8 | STATE STREET CORP | 1,296,209 | 89,245,000 | 2.63% | ||
| 9 | FRONTIER CAPITAL MANAGEMENT CO LLC | 1,284,844 | 88,462,000 | 2.61% | ||
| 10 | BlackRock Institutional Trust Company, N.A. | 1,132,117 | 77,946,000 | 2.30% | ||
| 11 | BANK OF AMERICA CORP /DE/ | 1,126,590 | 77,565,000 | 2.29% | ||
| 12 | RENAISSANCE TECHNOLOGIES LLC | 1,084,478 | 74,666,000 | 2.20% | ||
| 13 | SCHRODER INVESTMENT MANAGEMENT GROUP | 1,061,400 | 73,077,000 | 2.16% | ||
| 14 | CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 1,039,502 | 71,570,000 | 2.11% | ||
| 15 | Bank of New York Mellon Corp | 990,100 | 68,168,000 | 2.01% | ||
| 16 | COLUMBUS CIRCLE INVESTORS | 937,317 | 64,534,000 | 1.90% | ||
| 17 | ALLIANCEBERNSTEIN L.P. | 898,455 | 61,859,000 | 1.83% | ||
| 18 | JPMORGAN CHASE & CO | 893,144 | 61,493,000 | 1.81% | ||
| 19 | FMR LLC | 841,420 | 57,932,000 | 1.71% | ||
| 20 | NORTHERN TRUST CORP | 691,901 | 47,638,000 | 1.41% | ||
| 21 | Numeric Investors LLC | 632,900 | 43,575,000 | 1.29% | ||
| 22 | NEXT CENTURY GROWTH INVESTORS LLC | 525,086 | 36,152,000 | 1.07% | ||
| 23 | DEUTSCHE BANK AG\ | 462,111 | 31,813,000 | 0.94% | ||
| 24 | AMERIPRISE FINANCIAL INC | 459,498 | 31,637,000 | 0.93% | ||
| 25 | VICTORY CAPITAL MANAGEMENT INC | 457,840 | 31,522,000 | 0.93% | ||
| 26 | 1832 Asset Management L.P. | 467,600 | 31,302,000 | 0.92% | ||
| 27 | LORD, ABBETT & CO. LLC | 443,434 | 30,530,000 | 0.90% | ||
| 28 | NEW YORK STATE COMMON RETIREMENT FUND | 441,586 | 30,403,000 | 0.90% | ||
| 29 | Invesco Ltd. | 432,051 | 29,747,000 | 0.88% | ||
| 30 | NORGES BANK | 356,526 | 24,547,000 | 0.72% | ||
| 31 | Tekla Capital Management LLC | 347,901 | 23,953,000 | 0.71% | ||
| 32 | Copper Rock Capital Partners, LLC | 324,666 | 22,353,000 | 0.66% | ||
| 33 | Commonwealth Equity Services, Inc | 322,286 | 22,189,000 | 0.65% | ||
| 34 | GUGGENHEIM CAPITAL LLC | 316,888 | 21,817,000 | 0.64% | ||
| 35 | CHARTWELL INVESTMENT PARTNERS, LLC | 312,868 | 21,541,000 | 0.64% | ||
| 36 | GEODE CAPITAL MANAGEMENT, LLC | 311,899 | 21,473,000 | 0.63% | ||
| 37 | MASSACHUSETTS FINANCIAL SERVICES CO /MA/ | 310,756 | 21,395,000 | 0.63% | ||
| 38 | PANAGORA ASSET MANAGEMENT INC | 297,248 | 20,466,000 | 0.60% | ||
| 39 | THOMPSON SIEGEL & WALMSLEY LLC | 269,254 | 18,538,000 | 0.55% | ||
| 40 | RUSSELL FRANK CO/ | 265,615 | 18,285,000 | 0.54% | ||
| 41 | MORGAN STANLEY | 248,398 | 17,102,000 | 0.50% | ||
| 42 | GLENMEDE TRUST CO NA | 247,182 | 17,016,000 | 0.50% | ||
| 43 | TIAA CREF INVESTMENT MANAGEMENT LLC | 241,625 | 16,636,000 | 0.49% | ||
| 44 | CANADA PENSION PLAN INVESTMENT BOARD | 240,428 | 16,553,000 | 0.49% | ||
| 45 | Jupiter Investment Management Ltd | 236,445 | 16,279,000 | 0.48% | ||
| 46 | PFM Health Sciences, LP | 228,635 | 15,742,000 | 0.46% | ||
| 47 | BlackRock Investment Management, LLC | 226,517 | 15,596,000 | 0.46% | ||
| 48 | ROTHSCHILD & CO ASSET MANAGEMENT US INC. | 221,204 | 15,230,000 | 0.45% | ||
| 49 | NOMURA HOLDINGS INC | 211,727 | 14,583,000 | 0.43% | ||
| 50 | QS Investors, LLC | 210,480 | 14,492,000 | 0.43% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
