| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | ORBIMED ADVISORS LLC | 3,395,000 | 10,355,000 | 33.72% | ||
| 2 | Opaleye Management Inc. | 2,150,000 | 6,560,000 | 21.36% | ||
| 3 | JENNISON ASSOCIATES LLC | 1,762,785 | 5,376,000 | 17.51% | ||
| 4 | Cortina Asset Management, LLC | 1,741,407 | 5,311,000 | 17.29% | ||
| 5 | DAFNA Capital Management LLC | 286,724 | 875,000 | 2.85% | ||
| 6 | SOPHROSYNE CAPITAL LLC | 168,100 | 511,000 | 1.66% | ||
| 7 | NOMURA HOLDINGS INC | 100,000 | 315,000 | 1.03% | ||
| 8 | OPPENHEIMER & CO INC | 101,100 | 308,000 | 1.00% | ||
| 9 | GOLDMAN SACHS GROUP INC | 78,941 | 241,000 | 0.78% | ||
| 10 | Alpine Global Management, LLC | 75,000 | 229,000 | 0.75% | ||
| 11 | VANGUARD GROUP INC | 59,530 | 182,000 | 0.59% | ||
| 12 | HighTower Advisors, LLC | 35,375 | 108,000 | 0.35% | ||
| 13 | GEODE CAPITAL MANAGEMENT, LLC | 34,414 | 104,000 | 0.34% | ||
| 14 | NORTHERN TRUST CORP | 29,199 | 89,000 | 0.29% | ||
| 15 | Weiss Multi-Strategy Advisers LLC | 25,002 | 76,000 | 0.25% | ||
| 16 | UBS AG | 16,750 | 51,000 | 0.17% | ||
| 17 | MORGAN STANLEY | 3,400 | 10,000 | 0.03% | ||
| 18 | Creative Planning | 1,500 | 5,000 | 0.02% | ||
| 19 | WELLS FARGO & COMPANY/MN | 1,000 | 3,000 | 0.01% | ||
| 20 | Tower Research Capital LLC (TRC) | 201 | 1,000 | 0.00% | ||
| 21 | CITIGROUP INC | 123 | 0 | 0.00% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
