| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | ORBIMED ADVISORS LLC | 3,395,000 | 10,015,000 | 30.63% | ||
| 2 | Cortina Asset Management, LLC | 2,311,329 | 6,818,000 | 20.85% | ||
| 3 | Opaleye Management Inc. | 2,180,000 | 6,431,000 | 19.67% | ||
| 4 | JENNISON ASSOCIATES LLC | 1,574,855 | 4,646,000 | 14.21% | ||
| 5 | NOMURA HOLDINGS INC | 576,705 | 1,685,000 | 5.15% | ||
| 6 | Catalyst Capital Advisors LLC | 483,036 | 1,425,000 | 4.36% | ||
| 7 | DAFNA Capital Management LLC | 84,226 | 248,000 | 0.76% | ||
| 8 | BlackRock Fund Advisors | 77,117 | 227,000 | 0.69% | ||
| 9 | Alpine Global Management, LLC | 75,000 | 221,000 | 0.68% | ||
| 10 | GEODE CAPITAL MANAGEMENT, LLC | 71,907 | 212,000 | 0.65% | ||
| 11 | VANGUARD GROUP INC | 62,230 | 184,000 | 0.56% | ||
| 12 | GOLDMAN SACHS GROUP INC | 56,937 | 168,000 | 0.51% | ||
| 13 | NORTHERN TRUST CORP | 29,533 | 87,000 | 0.27% | ||
| 14 | HighTower Advisors, LLC | 28,375 | 84,000 | 0.26% | ||
| 15 | UBS AG | 26,861 | 79,000 | 0.24% | ||
| 16 | Weiss Multi-Strategy Advisers LLC | 25,000 | 74,000 | 0.23% | ||
| 17 | OPPENHEIMER & CO INC | 18,101 | 53,000 | 0.16% | ||
| 18 | BlackRock Investment Management, LLC | 4,730 | 14,000 | 0.04% | ||
| 19 | MORGAN STANLEY | 4,400 | 13,000 | 0.04% | ||
| 20 | WELLS FARGO & COMPANY/MN | 2,000 | 6,000 | 0.02% | ||
| 21 | Creative Planning | 1,500 | 4,000 | 0.01% | ||
| 22 | CITIGROUP INC | 1,002 | 3,000 | 0.01% | ||
| 23 | Ground Swell Capital, LLC | 281 | 1,000 | 0.00% | ||
| 24 | BANK OF AMERICA CORP /DE/ | 352 | 1,000 | 0.00% | ||
| 25 | Tower Research Capital LLC (TRC) | 1 | 0 | 0.00% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
