| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | ORBIMED ADVISORS LLC | 3,150,000 | 6,930,000 | 29.56% | ||
| 2 | Cortina Asset Management, LLC | 2,352,158 | 5,175,000 | 22.07% | ||
| 3 | Opaleye Management Inc. | 2,088,500 | 4,594,700 | 19.60% | ||
| 4 | JENNISON ASSOCIATES LLC | 1,577,211 | 3,470,000 | 14.80% | ||
| 5 | Catalyst Capital Advisors LLC | 493,036 | 1,085,000 | 4.63% | ||
| 6 | BRIDGEWAY CAPITAL MANAGEMENT, LLC | 230,000 | 506,000 | 2.16% | ||
| 7 | VANGUARD GROUP INC | 136,093 | 299,000 | 1.28% | ||
| 8 | Alpine Global Management, LLC | 125,000 | 275,000 | 1.17% | ||
| 9 | GEODE CAPITAL MANAGEMENT, LLC | 82,592 | 181,000 | 0.77% | ||
| 10 | BlackRock Fund Advisors | 71,898 | 158,000 | 0.67% | ||
| 11 | GOLDMAN SACHS GROUP INC | 67,491 | 148,000 | 0.63% | ||
| 12 | DAFNA Capital Management LLC | 63,700 | 140,000 | 0.60% | SH | |
| 13 | Virtu KCG Holdings LLC | 61,894 | 136,000 | 0.58% | ||
| 14 | HighTower Advisors, LLC | 38,475 | 85,000 | 0.36% | ||
| 15 | NORTHERN TRUST CORP | 29,421 | 65,000 | 0.28% | ||
| 16 | Weiss Multi-Strategy Advisers LLC | 25,000 | 55,000 | 0.23% | ||
| 17 | Platinum Management (NY) LLC | 24,453 | 54,000 | 0.23% | ||
| 18 | UBS AG | 22,750 | 50,000 | 0.21% | ||
| 19 | MORGAN STANLEY | 10,405 | 23,000 | 0.10% | ||
| 20 | BlackRock Investment Management, LLC | 4,762 | 10,000 | 0.04% | ||
| 21 | Creative Planning | 1,250 | 3,000 | 0.01% | ||
| 22 | CITIGROUP INC | 274 | 1,000 | 0.00% | ||
| 23 | Tower Research Capital LLC (TRC) | 1 | 0 | 0.00% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
