| 1 |
BVF INC/IL |
2,607,091 |
2,946,000 |
41.81% |
|
|
| 2 |
SABBY MANAGEMENT, LLC |
1,011,550 |
1,143,000 |
16.22% |
|
|
| 3 |
PANAGORA ASSET MANAGEMENT INC |
562,069 |
635,000 |
9.01% |
|
|
| 4 |
VANGUARD GROUP INC |
543,285 |
614,000 |
8.71% |
|
|
| 5 |
BlackRock Fund Advisors |
365,086 |
413,000 |
5.86% |
|
|
| 6 |
NORTHERN TRUST CORP |
166,036 |
188,000 |
2.67% |
|
|
| 7 |
BlackRock Institutional Trust Company, N.A. |
125,008 |
141,000 |
2.00% |
|
|
| 8 |
GEODE CAPITAL MANAGEMENT, LLC |
109,315 |
123,000 |
1.75% |
|
|
| 9 |
THOMPSON DAVIS & CO., INC. |
101,000 |
114,000 |
1.62% |
|
|
| 10 |
TIAA CREF INVESTMENT MANAGEMENT LLC |
69,295 |
78,000 |
1.11% |
|
|
| 11 |
Bank of New York Mellon Corp |
65,413 |
74,000 |
1.05% |
|
|
| 12 |
CHARLES SCHWAB INVESTMENT MANAGEMENT INC |
60,501 |
69,000 |
0.98% |
|
|
| 13 |
STATE STREET CORP |
59,919 |
67,000 |
0.95% |
|
|
| 14 |
BlackRock Investment Management, LLC |
42,996 |
49,000 |
0.70% |
|
|
| 15 |
Tower Research Capital LLC (TRC) |
41,720 |
47,000 |
0.67% |
|
|
| 16 |
SG Americas Securities, LLC |
41,055 |
46,000 |
0.65% |
|
|
| 17 |
CALIFORNIA PUBLIC EMPLOYEES RETIREMENT SYSTEM |
39,100 |
44,000 |
0.62% |
|
|
| 18 |
CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM |
28,362 |
32,000 |
0.45% |
|
|
| 19 |
Biondo Investment Advisors, LLC |
23,000 |
26,000 |
0.37% |
|
|
| 20 |
JANE STREET GROUP, LLC |
22,255 |
25,000 |
0.35% |
|
|
| 21 |
TEACHERS ADVISORS, LLC |
20,996 |
24,000 |
0.34% |
|
|
| 22 |
GOLDMAN SACHS GROUP INC |
20,326 |
23,000 |
0.33% |
|
|
| 23 |
RHUMBLINE ADVISERS |
13,835 |
16,000 |
0.23% |
|
|
| 24 |
Nationwide Fund Advisors |
11,420 |
13,000 |
0.18% |
|
|
| 25 |
CREDIT SUISSE AG/ |
11,092 |
12,000 |
0.17% |
|
|
| 26 |
TFS CAPITAL LLC |
10,337 |
12,000 |
0.17% |
|
|
| 27 |
UBS AG |
10,316 |
12,000 |
0.17% |
|
|
| 28 |
AMERICAN INTERNATIONAL GROUP, INC. |
10,098 |
11,411 |
0.16% |
|
|
| 29 |
PARAMETRIC PORTFOLIO ASSOCIATES LLC |
10,086 |
11,000 |
0.16% |
|
|
| 30 |
BLACKROCK ADVISORS LLC |
6,473 |
7,000 |
0.10% |
|
|
| 31 |
STRS OHIO |
5,300 |
6,000 |
0.09% |
|
|
| 32 |
MANUFACTURERS LIFE INSURANCE COMPANY, THE |
4,123 |
5,000 |
0.07% |
|
|
| 33 |
GROUP ONE TRADING LLC |
3,300 |
4,000 |
0.06% |
|
|
| 34 |
MORGAN STANLEY |
3,629 |
4,000 |
0.06% |
|
|
| 35 |
BARCLAYS PLC |
3,088 |
3,000 |
0.04% |
|
|
| 36 |
Ground Swell Capital, LLC |
1,402 |
2,000 |
0.03% |
|
|
| 37 |
ALLIANCEBERNSTEIN L.P. |
1,700 |
2,000 |
0.03% |
|
|
| 38 |
PNC FINANCIAL SERVICES GROUP, INC. |
1,000 |
1,000 |
0.01% |
|
|
| 39 |
LADENBURG THALMANN FINANCIAL SERVICES INC. |
500 |
1,000 |
0.01% |
|
|
| 40 |
AMERIPRISE FINANCIAL INC |
840 |
1,000 |
0.01% |
|
|
| 41 |
CITIGROUP INC |
538 |
1,000 |
0.01% |
|
|
| 42 |
WELLS FARGO & COMPANY/MN |
712 |
1,000 |
0.01% |
|
|
| 43 |
BNP PARIBAS FINANCIAL MARKETS |
301 |
340 |
0.00% |
|
|
| 44 |
DEUTSCHE BANK AG\ |
145 |
0 |
0.00% |
|
|
| 45 |
OPTIMUM INVESTMENT ADVISORS |
325 |
0 |
0.00% |
|
|
| 46 |
MYCIO WEALTH PARTNERS, LLC |
155 |
0 |
0.00% |
|
|
| 47 |
BANK OF AMERICA CORP /DE/ |
158 |
0 |
0.00% |
|
|
