| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | BVF INC/IL | 1,659,091 | 20,772,000 | 43.35% | ||
| 2 | BAKER BROS. ADVISORS LP | 400,000 | 5,008,000 | 10.45% | ||
| 3 | Alyeska Investment Group, L.P. | 355,087 | 4,446,000 | 9.28% | ||
| 4 | Informed Momentum Co LLC | 243,202 | 3,045,000 | 6.35% | ||
| 5 | WEXFORD CAPITAL LP | 200,000 | 2,504,000 | 5.23% | ||
| 6 | SPHERA FUNDS MANAGEMENT LTD. | 200,000 | 2,504,000 | 5.23% | ||
| 7 | Biondo Investment Advisors, LLC | 143,775 | 1,800,000 | 3.76% | ||
| 8 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 126,161 | 1,580,000 | 3.30% | ||
| 9 | VANGUARD GROUP INC | 82,340 | 1,031,000 | 2.15% | ||
| 10 | GEODE CAPITAL MANAGEMENT, LLC | 57,441 | 719,000 | 1.50% | ||
| 11 | UBS AG | 41,433 | 519,000 | 1.08% | ||
| 12 | PANAGORA ASSET MANAGEMENT INC | 38,815 | 486,000 | 1.01% | ||
| 13 | GOLDMAN SACHS GROUP INC | 36,837 | 461,000 | 0.96% | ||
| 14 | DEUTSCHE BANK AG\ | 35,261 | 441,000 | 0.92% | ||
| 15 | CREDIT SUISSE AG/ | 33,400 | 418,000 | 0.87% | ||
| 16 | RUSSELL FRANK CO/ | 62,675 | 411,000 | 0.86% | ||
| 17 | JANE STREET GROUP, LLC | 24,819 | 311,000 | 0.65% | ||
| 18 | SOPHROSYNE CAPITAL LLC | 24,700 | 310,000 | 0.65% | ||
| 19 | NORTHERN TRUST CORP | 18,933 | 237,000 | 0.49% | ||
| 20 | BlackRock Group LTD | 17,653 | 221,000 | 0.46% | ||
| 21 | Spark Investment Management LLC | 14,200 | 176,000 | 0.37% | ||
| 22 | BlueCrest Capital Management LLP | 13,300 | 167,000 | 0.35% | ||
| 23 | GILDER GAGNON HOWE & CO LLC | 10,492 | 131,000 | 0.27% | ||
| 24 | WELLS FARGO & COMPANY/MN | 7,570 | 95,000 | 0.20% | ||
| 25 | BANK OF MONTREAL /CAN/ | 3,000 | 38,000 | 0.08% | ||
| 26 | MORGAN STANLEY | 2,958 | 37,000 | 0.08% | ||
| 27 | BlackRock Institutional Trust Company, N.A. | 1,755 | 22,000 | 0.05% | ||
| 28 | TradeLink Global Equity LLC | 1,000 | 13,000 | 0.03% | ||
| 29 | BARCLAYS PLC | 400 | 5,000 | 0.01% | ||
| 30 | OPTIMUM INVESTMENT ADVISORS | 325 | 4,000 | 0.01% | ||
| 31 | Tower Research Capital LLC (TRC) | 254 | 3,000 | 0.01% | ||
| 32 | BANK OF AMERICA CORP /DE/ | 100 | 1,000 | 0.00% | ||
| 33 | BlackRock Finance, Inc. | 13 | 0 | 0.00% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
