| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | SABBY MANAGEMENT, LLC | 1,902,800 | 4,243,000 | 23.66% | ||
| 2 | Senvest Management, LLC | 1,549,805 | 3,456,000 | 19.27% | ||
| 3 | Opaleye Management Inc. | 1,451,000 | 3,236,000 | 18.05% | ||
| 4 | ORBIMED ADVISORS LLC | 1,135,000 | 2,531,000 | 14.12% | ||
| 5 | BVF INC/IL | 800,000 | 1,784,000 | 9.95% | ||
| 6 | SPHERA FUNDS MANAGEMENT LTD. | 600,000 | 1,338,000 | 7.46% | ||
| 7 | DEUTSCHE BANK AG\ | 223,050 | 497,000 | 2.77% | ||
| 8 | PERCEPTIVE ADVISORS LLC | 179,041 | 399,000 | 2.23% | ||
| 9 | JANE STREET GROUP, LLC | 59,063 | 130,000 | 0.73% | ||
| 10 | CITADEL ADVISORS LLC | 32,373 | 72,000 | 0.40% | ||
| 11 | RENAISSANCE TECHNOLOGIES LLC | 26,800 | 60,000 | 0.33% | ||
| 12 | Benchmark Capital Advisors | 20,000 | 45,000 | 0.25% | ||
| 13 | Virtu KCG Holdings LLC | 18,640 | 41,000 | 0.23% | ||
| 14 | Bank of New York Mellon Corp | 17,800 | 40,000 | 0.22% | ||
| 15 | ROYAL BANK OF CANADA | 12,000 | 27,000 | 0.15% | ||
| 16 | MORGAN STANLEY | 9,391 | 21,000 | 0.12% | ||
| 17 | UBS AG | 2,967 | 7,000 | 0.04% | ||
| 18 | CITIGROUP INC | 826 | 2,000 | 0.01% | ||
| 19 | WELLS FARGO & COMPANY/MN | 1,000 | 2,000 | 0.01% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
