| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | Senvest Management, LLC | 3,326,688 | 7,019,000 | 26.05% | ||
| 2 | Broadfin Capital, LLC | 3,100,000 | 6,541,000 | 24.27% | ||
| 3 | BVF INC/IL | 1,501,000 | 3,167,000 | 11.75% | ||
| 4 | ORBIMED ADVISORS LLC | 1,135,000 | 2,395,000 | 8.89% | ||
| 5 | Alyeska Investment Group, L.P. | 750,000 | 1,583,000 | 5.87% | ||
| 6 | SABBY MANAGEMENT, LLC | 744,401 | 1,571,000 | 5.83% | ||
| 7 | DEUTSCHE BANK AG\ | 646,146 | 1,363,000 | 5.06% | ||
| 8 | MILLENNIUM MANAGEMENT LLC | 436,917 | 922,000 | 3.42% | ||
| 9 | MORGAN STANLEY | 343,465 | 725,000 | 2.69% | ||
| 10 | Opaleye Management Inc. | 250,000 | 528,000 | 1.96% | ||
| 11 | SPHERA FUNDS MANAGEMENT LTD. | 193,284 | 408,000 | 1.51% | ||
| 12 | MENTA CAPITAL LLC | 76,417 | 161,000 | 0.60% | ||
| 13 | ACADIAN ASSET MANAGEMENT LLC | 68,962 | 145,000 | 0.54% | ||
| 14 | Benchmark Capital Advisors | 40,000 | 84,000 | 0.31% | ||
| 15 | NEXT Financial Group, Inc | 37,500 | 79,000 | 0.29% | ||
| 16 | Virtu KCG Holdings LLC | 29,183 | 62,000 | 0.23% | ||
| 17 | JANE STREET GROUP, LLC | 18,203 | 39,000 | 0.14% | ||
| 18 | Bank of New York Mellon Corp | 17,800 | 38,000 | 0.14% | ||
| 19 | Cutter & CO Brokerage, Inc. | 15,000 | 32,000 | 0.12% | ||
| 20 | Kovack Advisors, Inc. | 14,335 | 30,000 | 0.11% | ||
| 21 | PNC FINANCIAL SERVICES GROUP, INC. | 10,000 | 21,000 | 0.08% | ||
| 22 | UBS Group AG | 7,927 | 17,000 | 0.06% | ||
| 23 | CITIGROUP INC | 4,997 | 11,000 | 0.04% | ||
| 24 | ROYAL BANK OF CANADA | 2,000 | 4,000 | 0.01% | ||
| 25 | WELLS FARGO & COMPANY/MN | 1,000 | 2,000 | 0.01% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
